Severe cognitive problems are common ; approximately 10 percent of all dementia cases are related to alcohol consumption, making it the second leading cause of dementia.

Severe erosion occurs in cases such as this, causing stream sedimentation and the loss of nutrient rich topsoil.

Severe cases will require admission to intensive care.

Severe cyanide poisoning, particularly during famines, is associated with outbreaks of a debilitating, irreversible paralytic disorder called konzo and, in some cases, death.

Severe, treatment-resistant cases may require surgery to mobilize the band.

Severe cases of psoriasis have been shown to affect health-related quality of life to an extent similar to the effects of other chronic diseases, such as depression, hypertension, congestive heart failure or type 2 diabetes.

Severe cases where there is an inability to remove the object may require cricothyrotomy.

Severe cases (" fecal impaction " or malignant constipation ) may exhibit symptoms of bowel obstruction ( vomiting, very tender abdomen ) and encopresis, where soft stool from the small intestine bypasses the mass of impacted fecal matter in the colon.

In 2003, following the outbreak of Severe acute respiratory syndrome ( SARS ) which had begun the prior year in Asia, and secondary cases elsewhere in the world, the World Health Organization issued a press release stating that a novel coronavirus identified by a number of laboratories was the causative agent for SARS.

Severe cases can require surgery.

Severe cases of PE can lead to collapse, abnormally low blood pressure, and sudden death.

Severe cases may require thrombolysis with drugs such as tissue plasminogen activator ( tPA ) or may require surgical intervention via pulmonary thrombectomy.

* Severe cases with hemorrhage: The PT and APTT are usually very prolonged and the fibrinogen level markedly reduced.

For example, von Oettingen recorded 47 fatal and 174 nonfatal cases of methyl bromide intoxication between 1899 and 1952 ... Severe poisoning with some fatalities resulted from soil disinfection by injection of methyl bromide into greenhouse soil.

Severe cases can exceed the instrument's measuring ability.

Severe cases may lead to delirium, coma and death after 5 – 7 days.

Severe cases are also more likely to occur in the very young, very old, and persons with immunodeficiency, such as HIV / AIDS patients.

Severe complications occur however in rare cases and these include blood clots, thrombosis, cardiac and pulmonary complications or infection.

Severe cases may require permanent ventilation or tracheostomy.

Severe adverse reactions are rare, but use of 2C-B has been linked to significant injury in some cases.

Severe cases can result in cell damage and death, with effects most often seen in the central nervous system, lungs and eyes.

Severe cases of this disorder can have highly restricting effects on a person's life.

Severe cases are known as cytokine storms.

Severe sickle cell crises, in some cases resulting in death, have been associated with the use of NEUPOGEN in patients with sickle cell disorders.

Severe acute withdrawal symptoms such as delerium tremens and seizures rarely occur after 1 week post cessation of alcohol.

Severe symptoms usually occur as a result of abrupt or over-rapid withdrawal.

Severe symptoms are most likely to occur in young children.

Severe blizzards can occur in the region.

Severe pains in the bones and muscles of the back and extremities occur, as do muscle spasms.

Severe reactions do occur with the fluoroquinolone class and can add significantly to the cost of care.

Severe back pain may occur in some patients at the onset of the disease.

Severe thunderstorms can occur at any time of the year though mainly during the spring months.

* Severe: pH below 7. 00, bicarbonate below 10, stupor or coma may occur

Severe thunderstorms can occur from any type of storm cell.

Severe complications, if they occur, are usually in the very old, the very young or those who are immunosuppressed.

Severe weather is not common in Wilkes but does occur.

Severe haemophiliacs have frequent serious bleeds ( 20 + times per year ), these bleeds often occur spontaneously without trauma or injury.

Severe floods occur on the lower reaches of the river about every 12 – 15 years, which sometimes wash out bridges.

Severe pneumonia requiring intensive-care support may also occur.

Severe instability can occur at transonic speeds.

Severe diseases, including pancreatitis, can occur.

Severe dehydration caused by the laxatives that are usually administered during the bowel preparation for colonoscopy also may occur.

Severe degrees of chordee are usually associated with hypospadias, but mild degrees of curvature may occur in many otherwise normal males.

Severe localised rainstorms (' cloudbursts ') may occur in the high country and have caused flash flooding including past inundations of Opotiki township.

Severe angioedema cases may require desensitization to the putative allergen, as mortality can occur.

Severe scoliosis is relatively uncommon, but probably does occur more often than in those without A-T. Spinal fusion is only rarely indicated.