Severe thunderstorms can occur from any type of storm cell.

Severe Mycoplasma infections may destroy a cell line.

Severe cases can result in cell damage and death, with effects most often seen in the central nervous system, lungs and eyes.

Severe defects of Okazaki fragment maturation may halt DNA replication and induce cell death.

Severe blood loss, white mucous membranes, and anemia or low packed cell volumes are common complications of the infection.

It had come as no great surprise to Matson that the hot water in the showers didn't work, that Loren Severe had thrown up all over the stairs, or that some thieving bastard of a cop had walked off with his cigarettes.

Severe weather is uncommon in the Chicago area, though there have been some exceptions such as the F4 tornado that devastated the south side of the city on April 21, 1967.

Severe back pain may occur in some patients at the onset of the disease.

Research programs, including field projects such as the VORTEX projects ( Verification of the Origins of Rotation in Tornadoes Experiment ), deployment of TOTO ( the TOtable Tornado Observatory ), Doppler On Wheels ( DOW ), and dozens of other programs, hope to solve many questions that still plague meteorologists .< ref name =" field programs history "> Universities, government agencies such as the National Severe Storms Laboratory, private-sector meteorologists, and the National Center for Atmospheric Research are some of the organizations very active in research ; with various sources of funding, both private and public, a chief entity being the National Science Foundation.

Severe cyanide poisoning, particularly during famines, is associated with outbreaks of a debilitating, irreversible paralytic disorder called konzo and, in some cases, death.

For example, von Oettingen recorded 47 fatal and 174 nonfatal cases of methyl bromide intoxication between 1899 and 1952 ... Severe poisoning with some fatalities resulted from soil disinfection by injection of methyl bromide into greenhouse soil.

Severe adverse reactions are rare, but use of 2C-B has been linked to significant injury in some cases.

Skin: Severe generalized skin reactions including toxic epidermal necrolysis ( some fatal ), Stevens-Johnson syndrome, and erythema multiforme ; photosensitivity ; urticaria ; rash ; skin inflammation ; pruritus ; petechiae ; purpura ; alopecia ; dry skin ; hyperhidrosis

Severe anti-German sentiment during World War I led some influential members of the public to quietly question the loyalty of the Royal Family, because they had a German or German-sounding name.

At 10AM on 11 May 1970, the SELS ( Severe Local Storms unit ) issued an outlook that stated that isolated thunderstorms were possible in the High Plains region of West Texas, and amended the outlook at 1: 25 PM to include the possibility that some of the storms may become severe.

The specific reduction mammoplasty procedure is determined by the volume of breast tissues ( glandular, adipose, skin ) to be resected ( cut and removed ) from each breast, and the degree of breast ptosis present: Pseudoptosis ( sagging of the inferior pole of the breast ; the nipple is at or above the inframammary fold ); Grade I: Mild ptosis ( the nipple is below the IMF, but above the lower pole of the breast ); Grade II: Moderate ptosis ( the nipple is below the IMF ; yet some lower-pole breast tissue hangs lower than the nipple ); Grade III: Severe ptosis ( the nipple is far below the IMF ; no breast tissue is below the nipple ).

Severe combined immunodeficiency ( SCID ) caused by T-cell deficiency is a disorder that was recently added to newborn screening programs in some regions of the United States.

# צער גדול / Tza ' ar Godol / Severe Pain ( Can in some cases be practically regarded as level 4 )

Severe flooding affected parts of Kingston, leaving some areas under of water.

Severe war damage caused the Stadtbahn system to be suspended in some areas until 27 May 1945.

Severe cognitive problems are common ; approximately 10 percent of all dementia cases are related to alcohol consumption, making it the second leading cause of dementia.

Severe erosion occurs in cases such as this, causing stream sedimentation and the loss of nutrient rich topsoil.

Severe cases will require admission to intensive care.

Severe, treatment-resistant cases may require surgery to mobilize the band.

Severe cases of psoriasis have been shown to affect health-related quality of life to an extent similar to the effects of other chronic diseases, such as depression, hypertension, congestive heart failure or type 2 diabetes.

Severe cases where there is an inability to remove the object may require cricothyrotomy.

Severe cases (" fecal impaction " or malignant constipation ) may exhibit symptoms of bowel obstruction ( vomiting, very tender abdomen ) and encopresis, where soft stool from the small intestine bypasses the mass of impacted fecal matter in the colon.

In 2003, following the outbreak of Severe acute respiratory syndrome ( SARS ) which had begun the prior year in Asia, and secondary cases elsewhere in the world, the World Health Organization issued a press release stating that a novel coronavirus identified by a number of laboratories was the causative agent for SARS.

Severe cases can require surgery.

Severe cases of PE can lead to collapse, abnormally low blood pressure, and sudden death.

Severe cases may require thrombolysis with drugs such as tissue plasminogen activator ( tPA ) or may require surgical intervention via pulmonary thrombectomy.

* Severe cases with hemorrhage: The PT and APTT are usually very prolonged and the fibrinogen level markedly reduced.

Severe cases can exceed the instrument's measuring ability.

Severe cases may lead to delirium, coma and death after 5 – 7 days.

Severe cases occur mostly in people who have had their spleen removed surgically.

Severe cases are also more likely to occur in the very young, very old, and persons with immunodeficiency, such as HIV / AIDS patients.

Severe complications occur however in rare cases and these include blood clots, thrombosis, cardiac and pulmonary complications or infection.

Severe cases may require permanent ventilation or tracheostomy.

Severe cases of this disorder can have highly restricting effects on a person's life.

Severe cases are known as cytokine storms.

Severe damage was sustained during Skylab launch and deployment, resulting in the loss of the station's micrometeroid shield / sun shade and one of its main solar panels.

Severe red-tape and licensed monopolies were set up to restrict the flow of trade, resulting in high retail prices for imported goods and limited demand.

* Severe vomiting and diarrhea, resulting in dehydration

Severe damage also occurred to stacks of hay and corn, resulting in severe starvation among livestock in the months following the storm.

Severe behavioral changes resulting from benzodiazepines have been reported including mania, schizophrenia, anger, impulsivity, and hypomania.

Severe nitrazepam overdose resulting in coma causes the central somatosensory conduction time ( CCT ) after median nerve stimulation to be prolonged and the N20 to be dispersed.

Severe flooding of the Millennium Ribble Link took place in 2003 / 2004 causing sever sedimentation to the channel and scour to by-wash weirs resulting in the Ribble Link becoming un-navigable.

Severe swelling can cause permanent damage to nerves, resulting in peripheral neuropathy.