Significant progress in Big Bang cosmology have been made since the late 1990s as a result of advances in telescope technology as well as the analysis of data from satellites such as COBE, the Hubble Space Telescope and WMAP.

Significant advances in the state-of-the-art in CSR have been achieved, and current efforts are focused on integrating speech recognition and natural language processing to allow spoken language interaction with a naval resource management system.

Significant progress came following the work of Louis Pasteur and his advances in microbiology, when the British surgeon Joseph Lister began experimenting with using phenol during surgery to prevent infections.

Significant contributions to the war effort included the development in 1940 of the cavity magnetron for radar, by the scientists John Randall and Harry Boot, at the University of Birmingham, and advances in communications technology and the ongoing mass production of valves, lamps and lighting equipment.

Significant advances are made in the sciences ( geography, astronomy, mathematics etc.

Significant advances in the fields of liver medicine ( hepatology ) and transplantation ; renal disease and dialysis ; haematology and haemophilia have been made at the Royal Free and the trust now treats all patients needing dialysis in north and central London.

Significant advances have been made in increasing the regulation of International Adoptions.

Significant advances have been made by the conservation movement, headed by Scott Jordan of the Tarkine National Coalition, to see the status of the Tarkine elevated to national park.

Significant advances in lunar theory made by the Arab astronomer, Ibn al-Shatir ( 1304 – 1375 ).

Significant correlations were also found in the auditory cortex, the somatosensory cortex related to the organs responsible for speech ( lips, tongue and mouth ), and frontal and parietal regions related to attention and performance monitoring.

Significant emphasis was also placed on town planning, with new conservation areas introduced and a new generation of new towns built, notably Milton Keynes – this trend itself a continuation of efforts initiated in the latter years of the preceding Conservative administration.

Significant new investment in tourism, including a 648-room Marriott hotel and convention center that opened in December 2002, as well as continued government efforts to diversify the economy, are expected to improve economic performance.

Significant events of the postwar era were the relocation of the university hospital from the city center to the Venusberg in 1949, the opening of the new university library in 1960 and the opening of a new building, the Juridicum, for the School of Law and Economics in 1967.

Significant new construction in the 1970s included the Elaine Langone Center, the Gerhard Fieldhouse, and the Computer Center.

Significant additions have been made to the campus since January 1999, when a powerful tornado destroyed nearly complete new school buildings and historic residential areas surrounding the downtown area.

Significant upgrades were temporarily put on hold following announcement of the new Angara launch vehicle.

Significant new features on the 1103A were its magnetic core memory, and the addition of interrupts to the processor.

Significant artists in this field are the German muralist Rainer Maria Latzke, who invented in the ' 90s a new method of producing illusion paintings, the Frescography and the English artist Graham Rust.

Significant cards included Yoda, another new version of Luke ( Son of Skywalker ) and all of the bounty hunters, their ships, and weapons ( except Boba Fett ).

Significant Other saw Limp Bizkit reaching a new level of commercial success.

Significant modifications include distinctive black boxes mounted on the rear of the turret bustle, originally expected to be the new air conditioning unit but instead likely contains Canadian Forces designated communications gear ( as they lined up with the new antennae stands ), and stand-off slat armour.

* 1993: Old aquarium was closed and construction of the new aquarium began, Zoo received two AAZPA awards: the Conservation Award for its black-footed ferret management program and the Significant Achievement Award for the Lied Jungle, world ’ s first artificially-inseminated gaur calf was born at the Zoo

Significant changes in the Leaving Certificate maths curriculum were reflected in two new textbooks produced by the Irish Christian Brothers.

Significant differences in the Isuzu-Lotus engine from the original include a new exhaust system, re-routed intake plumbing for better thermodynamic efficiency, improved engine suspension, and major modifications to the engine control unit to improve torque and boost response.

Significant parts of the constituency were transferred to the new Strangford constituency.

Significant libraries, schools, and mosques were built, as well as significant new fortifications.

The Birdhouse at Riverbanks ( opened 2002 ) was given a Significant Achievement Award by the AZA as one of the best new zoo exhibits in the United States and features a display of king, rockhopper and gentoo penguins.

Significant investment ( over £ 170 million ) is taking place at Pirbright with the development of new world class laboratory and animal facilities.

* Car And Driver Rates Honda Ridgeline # 1 Pickup, AutoWeek Editors ' Choice Award as the ' Most Significant ' new vehicle in the show

Significant renovations in the 1990s and 2000s resulted in the construction of large additions to the north and south of the building, the refurbishment and enlargement of existing rooms, and the addition of 60 new guestrooms, new meeting rooms and a new fitness facility which finished in 2002.

Significant are such canvases as `` Bleeker Street, Saturday Night '', with its typically American crowd ( Sloan never went abroad ) ; ;

Significant alcohol intake produces changes in the brain's structure and chemistry, though some alterations occur with minimal use of alcohol over a short term period, such as tolerance and physical dependence.

Significant changes came in 1910 with the reform of the Roman Breviary by Pope Pius X.

Significant trade with neighbouring countries, for example, exports of camels and other livestock to neighbouring states, such as Libya, and imports of manufactured goods, are conducted " informally " and probably not fully recorded.

Significant tunnel and bridge construction projects in the south of Dalmatia are planned, such as the Biokovo tunnel near Makarska, which will connect the panoramic seashore road with the future A1, and a long Pelješac bridge, connecting the Pelješac peninsula to the Croatian mainland.

" Significant amounts " of hexavalent chromium were found in the water of more than 40 homes in the area, some of which have now been fitted with state-monitored filters on their water supply.

* African festivals Significant African festivals based on the continent include the biannual Panafrican Film and Television Festival of Ouagadougou FESPACO in Burkina Faso, the annual Durban International Film Festival which has grown in importance for industry with the addition of a co-production forum and Talent Campus.

Significant failure of monsoon rains historically meant drought and famine while above-normal rains still cause flooding and landslides with losses in human lives, farmland and buildings.

Significant progress has also been made in bringing the world of UML modeling and the Semantic Web together through the adoption of the Ontology Definition Metamodel which relates UML models in a standard way with RDF and Web Ontology Language ( OWL ) models.

Significant contributions to oceanographic knowledge were made by the voyages of HMS Beagle in the 1830s, with Charles Darwin aboard ; HMS Challenger during the 1870s ; the USS Tuscarora ( 1873 – 76 ); and the German Gazelle ( 1874 – 76 ).

Significant privatizations of this nature occurred from 1760 to 1820, coincident with the industrial revolution in that country.

Significant privatization of state owned enterprises in Eastern and Central Europe and the former Soviet Union was undertaken in the 1990s with assistance from the World Bank, the U. S. Agency for International Development, the German Treuhand, and other governmental and nongovernmental organizations.

Significant differences remain with Myanmar over boundary alignment and the handling of ethnic rebels, refugees and illegal drug trade, in addition to mineral exploration and fishing rights.

The Fermi-1 commercial fast reactor prototype used HEU with 26. 5 % < sup > 235 </ sup > U. Significant quantities of HEU are used in the production of medical isotopes, for example molybdenum-99 for technetium-99m generators.

Significant problems with the metric of this form stem from the fact that all known warp drive spacetimes violate various energy conditions.

These " Bloomsbury assumptions " are also reflected in members ' criticisms of materialistic realism in painting and fiction, influenced above all by Clive Bell's " concept of ' Significant Form ', which separated and elevated the concept of form above content in works of art ": it has been suggested that, with their " focus on form ... Bell's ideas have come to stand in for, perhaps too much so, the aesthetic principles of the Bloomsbury Group ".

Significant contact with Tatars and Turks resulted in many Turkic words, particularly those involving military matters and steppe industry, being adopted into the Ukrainian language.

Significant amounts of teaching occurred in the museum as well with students claiming they learnt far more in the museum than they ever did in the lecture theatre.

Significant numbers of British Churchill and Matilda tanks along with US M3 Lee were shipped to the USSR after becoming obsolete on the African Front with the Churchills supplied by the arctic convoys seeing action around Leningrad while tanks shipped by the Persian route supplied the Caucasian Front.

Significant events of the latter variety occurred in Colorado and Kansas in May 2004 with winds to 100 mph ( 161 km / h ), Minnesota and Wisconsin in June 2004 causing significant damage, and the upper Middle West in May 1988, notable for strong electrification and lightning activity and by one estimate reaching 30, 000 ft ( 9, 144 m ) or more.

Significant growth in real estate prices continues, along with other major Romanian cities, as investor sentiment remains high, given the large foreign direct investment influx, recent accession to the European Union and forthcoming airport.