Significant contributions to noise pollution are made by internal combustion engines.

Significant angulation and deformity may require an open reduction and internal fixation or external fixation.

Significant angulation and deformity may require an open reduction and internal fixation.

* Iran: Significant land reform in Iran took place under the Shah as part of the socio-economic reforms of the White Revolution, begun in 1962, and agreed upon through a public referendum.

Significant reforms and post-World War II industrialization took place during this time.

Significant accomplishments during Jelks ' administration include the passage of legislation limiting and regulating child labor ; the establishment of the State Textbook Commission ; the reforms of the State Railroad Commission and the convict lease system ; the renovation and expansion of the State Capitol, and the creation of Houston County.

Significant differences from TCP were:

Significant amounts of energy and time were devoted to support and foster formal study of the balalaika, from which highly skilled ensemble groups such as the Osipov State Balalaika Orchestra emerged.

Significant wars were fought in Britain, where his general Agricola attempted to conquer Caledonia ( Scotland ), and in Dacia, where Domitian was unable to procure a decisive victory against king Decebalus.

" Significant amounts " of hexavalent chromium were found in the water of more than 40 homes in the area, some of which have now been fitted with state-monitored filters on their water supply.

Significant results were produced by Croatian mathematician Danilo Blanuša, who discovered two snarks in the 1940s, now known as Blanuša snarks ; prior to Blanuša's discovery, the only known snark was the Petersen graph ( Weisstein ).

Significant interpretations of his writings were produced by such sociological luminaries as Talcott Parsons and C. Wright Mills.

Significant contributions to oceanographic knowledge were made by the voyages of HMS Beagle in the 1830s, with Charles Darwin aboard ; HMS Challenger during the 1870s ; the USS Tuscarora ( 1873 – 76 ); and the German Gazelle ( 1874 – 76 ).

Significant amounts of the Soviet resources were allocated in aid to the other socialist states.

Significant events in the early development of rugby football were the production of the first set of written football laws at Rugby School in 1845, which was followed by the ' Cambridge Rules ' drawn up in 1848.

Significant amendments were made to the Constitution in 1991, and there have been a number of judicial interpretations made to take into account the fact that the Constitution covers a much smaller area than originally envisioned.

Significant were the contributions of Nicolas Jenson, Francesco Griffo, Aldus Manutius, and other printers of late fifteenth-century Europe.

Significant numbers of British Churchill and Matilda tanks along with US M3 Lee were shipped to the USSR after becoming obsolete on the African Front with the Churchills supplied by the arctic convoys seeing action around Leningrad while tanks shipped by the Persian route supplied the Caucasian Front.

Significant changes to the cathedral were made by the architect James Wyatt in 1790, including replacement of the original rood screen and demolition of the bell tower which stood about 320 feet ( 100 m ) north west of the main building.

Significant collections of Tiffany windows outside the United States are the 17 windows in the former Erskine and American United Church, now part of the Montreal Museum of Fine Arts in Montreal, Canada, and the two windows in the American Church in Paris, on the Quai d ' Orsay, which have been classified as National Monuments by the French government ; these were commissioned by Rodman Wanamaker in 1901 for the original American Church building on the right bank of the Seine.

Significant Huguenot settlements were in Dublin, Cork, Portarlington, Lisburn, Waterford and Youghal.

Significant early contributions to New Keynesian theory were compiled in 1991 by editors N. Gregory Mankiw and David Romer in New Keynesian Economics, volumes 1 and 2.

Significant events of the postwar era were the relocation of the university hospital from the city center to the Venusberg in 1949, the opening of the new university library in 1960 and the opening of a new building, the Juridicum, for the School of Law and Economics in 1967.

Significant evidence of this mining activity remains in the cave, including evidence of large amounts of saltpeter-bearing dirt that were removed, pick marks in the dirt, and an elaborate system of trails used by the miners.

* Significant portions of Fried Green Tomatoes were filmed in Newnan and Senoia.

Significant damage to an industrial plant with injuries, trapped people and destroyed homes were reported in Madison Parish near the Louisiana-Mississippi state line.

Significant gold mines in the nearby Santa Rosa Mountains were the National that produced in excess of 200, 000 ounces, and the Buckskin National that produced 24, 000 ounces of gold and 300, 000 ounces of silver over the period 1906 – 1941.

Significant portions of the 1961 film The Intruder ( Directed by Roger Corman and starring William Shatner ) were filmed in East Prairie.

Significant growth in the area, aided its proximity to Abilene, began to occur in the late 1980s and by 1992 there were 1, 441 people living in Potosi.

Significant changes in its management and language were brought in 1515 by Mahmoud Pasha Elekhani.

Significant emphasis was also placed on town planning, with new conservation areas introduced and a new generation of new towns built, notably Milton Keynes – this trend itself a continuation of efforts initiated in the latter years of the preceding Conservative administration.

Significant changes introduced into the 1968 document included Article 6, which committed the state to adhere to the " principles of socialist internationalism " and to devote special attention to its " fraternal ties " with the Soviet Union ; Article 9, which based the national economy on the " socialist ownership of the means of production "; Article 20, which under pressure from the churches granted freedom of conscience and belief ; Article 21, which maintained that the " basic rights " of citizenship were inseparably linked with " corresponding obligations "; and Article 47, which declared that the principle of " democratic centralism " is the authoritative maxim for the construction of the socialist state.

As Youngblood # 1 is the comic book that introduced Image Comics, it is ranked # 19 on Comic Book Resources's 2008 chronological list of the 20 Most Significant Comics.

Significant progress came following the work of Louis Pasteur and his advances in microbiology, when the British surgeon Joseph Lister began experimenting with using phenol during surgery to prevent infections.

Significant exceptions before 1800 can be found in Purcell's works, German opera of Hamburg during the Baroque, ballad opera and Singspiel of the 18th century, etc.

Significant events shape the period during which Yoshiharu was shogun:

Significant urban growth occurred in the 1920s, and during the 1930s to 1950s large-scale growth occurred.

Significant numbers of Adiabene population follow her, later also providing limited support for Jews during Jewish-Roman wars.

Significant concern was raised during the 1960s, with developers threatening the destruction of historical buildings, especially in Sydney.

Significant canyon-shaping events occurred as recently as 15, 000 years ago during a massive outburst flood from Glacial Lake Bonneville in Utah.

Significant former members include bass guitarist Derek Forbes and keyboard player Michael MacNeil ( the latter credited as a significant band composer during the band's rise in the 1980s ).

Significant opposition to the Iraq War occurred worldwide, both before and during the initial 2003 invasion of Iraq by the United States, United Kingdom, and smaller contingents from other nations, and throughout the subsequent occupation.

Significant events shape the period during which Yoshiaki was shogun:

Significant progress in science was made in the Muslim world during the Middle Ages, especially during the Islamic Golden Age, which is considered a major period in the history of science.

Significant events shaped the period during which Yoshiteru was shogun:

Significant events shape the period during which Yoshizumi was shogun:

Significant events which shaped the period during which Yoshitane was shogun:

Significant events shape the period during which Yoshihisa was shogun:

Significant events which shaped the period during which Yoshimasa was shogun:

Significant events which shaped the period during which Yoshikatsu was shogun:

Significant events which shaped the period during which Yoshinori was shogun:

Significant events shape the period during which Yoshikazu was shogun:

Significant events shape the period during which Yoshimochi was shogun:

Significant events shape the period during which Yoshimitsu was shogun:

Significant events shape the period during which Yoshiakira was shogun: