Since enzymes are selective for their substrates and speed up only a few reactions from among many possibilities, the set of enzymes made in a cell determines which metabolic pathways occur in that cell.

Since fermentation was a major metabolic pathway of cancer cells, Warburg reported cancer cells maintain a lower pH, as low as 6. 0, due to lactic acid production and elevated CO < sub > 2 </ sub >.

Since the heart has to work harder to meet the normal metabolic demands, it is incapable of meeting the metabolic demands of the body during exercise.

Since F is the strongest oxidizer known currently, it is immune to phase 1 metabolic reactions, which are generally oxidation reactions, in the liver.

Since cells use these metabolic networks for their survival, changes can have drastic effects on the cells ' ability to survive.

Since hypertension is related to all other conditions of metabolic syndrome it can then be extrapolated that cation transport is ubiquitously associated with obesity, dyslipidemia, and glucose intolerance as well.

Since the basal metabolic rate is now lower than the rate at the initial start of the diet in the individual, further weight gain occurs as the body is " less efficient " than it was before in burning calories.

Since these are the two principal metabolic mechanisms by which the liver supplies glucose to the rest of the body during periods of fasting, it causes severe hypoglycemia.

Since the load L, under actual cutting conditions is caused by Af, it can be seen that Af

Since Fogg's was a one-man, one-plane flying service, this meant that he would have to do both trips, flying alone 600 miles a day, under sub-freezing temperature conditions.

Since conference and of the Food and Agriculture Organization's publication World Festival of Trees, and a resolution of the United Nations in 1954: " The Conference, recognising the need of arousing mass consciousness of the aesthetic, physical and economic value of trees, recommends a World Festival of Trees to be celebrated annually in each member country on a date suited to local conditions "; it has been adopted by the Netherlands.

Since gaining independence from the United Kingdom in 1960, Cyprus has had a record of successful economic performance, reflected in strong growth, full employment conditions and relative stability.

Since acyl chlorides and acid anhydrides also react with water, anhydrous conditions are preferred.

Since poses were chosen to produce the most convincing images of states of mind and psychological conditions, as in Ashes, the figures impart a monumental, static quality.

Since E. histolytica does not form cysts in the absence of bacteria, E. invadens has become used as a model for encystation studies as it will form cysts under axenic growth conditions, which simplifies analysis.

Since these properties are often used as reference values it is very common to quote them for a standardized set of environmental parameters, or standard conditions, which is typically a temperature of and a pressure of either or.

Since the early history of domestication of the horse, working animals were found to be exposed to many conditions that created breakage or excessive hoof wear.

Since the publication of the History of Trade Unionism ( 1894 ) by Sidney and Beatrice Webb, the predominant historical view is that a trade union " is a continuous association of wage earners for the purpose of maintaining or improving the conditions of their employment.

Since 2009 thousands of established immigrants began to leave, although some that did continued to maintain homes in Spain due to poor conditions in their country of origin.

Since they can be used only once, fusees nowadays are usually intended for emergency use ( as opposed to the incandescent lanterns typically used during normal operating conditions ).

Since individual harmonic amplitudes are measured, it is required that the manufacturer disclose the test signal frequency range, level and gain conditions, and number of measurements taken.

Since these cirrus clouds arrive in advance of the frontal system or tropical cyclone, they indicate that the weather conditions may soon deteriorate.

Since walleyes have excellent visual acuity under low illumination levels, they tend to feed more extensively at dawn and dusk, on cloudy or overcast days and under choppy conditions when light penetration into the water column is disrupted.

Since the string is tied down at the ends, u must also satisfy the boundary conditions

Since these satisfy the Schrödinger equation-the solutions to Schrödinger's equation for a given situation will not only be the plane waves used to obtain it, but any wavefunctions which satisfy the Schrödinger's equation prescribed by the system, in addition to the relevant boundary conditions.

Since the geometric line of sight passes at varying heights over the Earth, the propagating radio wave encounters slightly different propagation conditions over the path.

Since cannas have very hard and durable seed coverings, it is likely that seed remains would have survived in the right conditions and been found by archaeologists in the Old World.

Since most macroeconomic models today study decisions over many periods, the expectations of workers, consumers and firms about future economic conditions are an essential part of the model.

Since execution of rungs is sequential within a program and may be undefined or obscure within a rung, some logic race conditions are possible which may produce unexpected results ; complex rungs are best broken into several simpler steps to avoid this problem.

Since 1985, the Government of Bolivia has implemented a far-reaching program of macroeconomic stabilization and structural reform aimed at maintaining price stability, creating conditions for sustained growth, and alleviating poverty.

Since the Second World War a doctrinal consensus has gradually developed that all general Royal Decrees have to conform to these conditions to be valid and that earlier practices to issue general Royal Decrees without meeting these three formalities — such Decrees, general or otherwise, are called " minor Royal Decrees " — can no longer result in regulations with binding force towards the citizen.

Since the research by Eleanor Rosch and George Lakoff in the 1970s, categorization can also be viewed as the process of grouping things based on prototypes-the idea of necessary and sufficient conditions is almost never met in categories of naturally occurring things.

Since macroeconomic behavior is derived from the interaction of the decisions of all these players, acting over time, in the face of uncertainty about future conditions, these models are classified as dynamic stochastic general equilibrium ( DSGE ) models.

Since civilizational change is the most difficult to perceive and analyze, it seldom is given adequate attention.

Since electrical stimulation of the posterior hypothalamus produces the effects of wakefulness while stimulation of the anterior hypothalamus induces sleep, it may be said that the reactivity of the whole organism is altered by a change in the autonomic reactivity of the hypothalamus.

Since the details of the elections were settled the change of government had no direct effect on the technical aspects of the elections, and may have been more important as an indication of royal displeasure with the U.N.F.P.

Since the change to better nutrition, he feels he can report on improvements in health, though he considers the following statements observations and not scientific proof.

( page 33 ) On the other hand, a little later on he says: `` Since 1692 a great but superficial change has wiped out God's beard and the Devil's horns, but the world is still gripped between two diametrically opposed absolutes.

Since this process does not involve any heat transfer or work, the First Law of Thermodynamics then implies that the net internal energy change of the system is zero.

Since 1977, New Zealand has celebrated Arbor Day on June 5, which is also World Environment Day, prior to then Arbor Day, in New Zealand, was celebrated on August 4 – which is rather late in the year for tree planting in New Zealand hence the date change.

Since the speed of sound varies with temperature, and is virtually stable with pressure change, sonic anemometers are also used as thermometers.

" Since no one in the raiding party is carrying any change, nor do they realize that there is nothing stopping them from simply riding around the tollbooth, Taggart sends someone back to town to " get a shitload of dimes ".

Since the shorts were produced during the rise of film noir in cinema, the change was usually represented as a stylized sequence: Clark Kent's silhouette is clearly seen behind a closed door's pebble glass window ( or a shadow thrown across a wall ) as he strips to his Superman costume.

Since his medium for bringing change was print and debate, it was natural for the origins of the Christadelphian body to be associated with journals and books, namely the Herald of the Kingdom and The Ambassador ( which later became The Christadelphian ).

Since he was Eleanor's vassal, many believed that it was she who had been ultimately responsible for the change in plan, and thus the massacre.

Since details of fact change constantly, these cannot be the most important.

Since history and memory ( representations of or belief about the past ) are distinct in all philosophy and ontology from plan, vision or intent ( representations of or will to change the future ), statements that confuse these are category errors: No statement about history or memory can imply a similar statement about a plan or vision or intent, nor vice versa-a distinction sometimes credited to Hume who distinguished also the morality of a statement from its truth.

According to the what economist Nicholas Barr describes as the " classical definition of income :" the 1938 Haig-Simons definition, " income may be defined as the ... sum of ( 1 ) the market value of rights exercised in consumption and ( 2 ) the change in the value of the store of property rights ..." Since the consumption potential of non-monetary goods, such as leisure, cannot be measured, monetary income may be thought of as a proxy for full income.

Since the reunification of Germany, Leipzig has undergone significant change with the restoration of some historical buildings, the demolition of others, and the development of a modern transport infrastructure.

Since behaviorists view the learning process as a change in behavior, educators arrange the environment to elicit desired responses through such devices as behavioral objectives, competency-based education, and skill development and training.

Since the foil must exert a force on the air to change its direction, the air must exert a force of equal magnitude but opposite direction on the foil.

Since energy is dependent on reference frame ( upon the observer ) it is convenient to formulate the equations of physics in a way such that mass values are invariant ( do not change ) between observers, and so the equations are independent of the observer.

Since the CFCs themselves are equally powerful greenhouse gases, the mere substitution of HFCs for CFCs does not significantly increase the rate of anthropogenic global warming, but over time a steady increase in their use could increase the danger that human activity will change the climate.

Since does not change, the accelerations are the same:

Since uplift and erosion are more or less in equilibrium in the Himalaya, rapid uplift is balanced by annual increments of cubic kilometers of sediments washing down from the mountains, then on the plains settling out of suspension on vast alluvial fans or inland deltas over which rivers meander and change course at least every few decades, causing some experts to question whether manmade embankments can contain the problem of flooding.

Since these were all individual compounds, he demonstrated that it was possible to make a chemical change in various fats ( which traditionally come from organic sources ), producing new compounds, without " vital force ".

Since the puppets are carved from wood, their facial expressions cannot change, but are stuck in the same exaggerated pose, which helps to deter any sense of realism and to distance the audience ( Crone 1065 ).

Since then, Postmodernism has involved theories that embrace and aim to create diversity, and it exhaults uncertainty, flexibility and change ( Hatuka & D ' Hooghe 2007 ).