Since patents and regulation ( e. g., U. S. Food and Drug Administration regulation in the U. S .) are very important issues for biotech enterprises, bioengineers are often required to have knowledge related to these issues.

Since there was no federal regulation in the USA concerning safety and effectiveness of drugs until the 1906 Food and Drugs Act and various medicine salesmen or manufacturers seldom had enough skills in analytical chemistry to analyze the contents of snake oil, it became the archetype of hoax.

Since the dissolution of the Soviet Union, environmental regulation is largely unchanged in Turkmenistan.

Since the time of the first Norman invaders from England, Ireland has been subject to control and regulation, firstly by England then latterly by Great Britain.

Since this is a rather new law so far, no further explanatory regulation regarding a detailed amount and applicable scope is promulgated guiding the application of this rule, so a court judge may have discretional power to decide punitive damages case by case under this new law.

Since the regulation of vascularization in the mature retina involves a balance between endogenous positive growth factors, such as vascular endothelial growth factor ( VEGF ) and inhibitors of angiogenesis, such as pigment epithelium-derived factor ( PEDF ), rAAV-mediated expression of PEDF, angiostatin, and the soluble VEGF receptor sFlt-1, which are all antiangiogenic proteins, have been shown to reduce aberrant vessel formation in animal models.

Since the states and territories are responsible for most public delivery and all regulation of providers, a central concept of the system is " national recognition " whereby the assessments and awards of any one registered training organisation must be recognised by all others and the decisions of any state or territory training authority must be recognised by the other states and territories.

Since there was no New Jersey State regulation for the disposal, this became a landmark case.

Since the passage of this act, the horses and burros have been managed under federal law and Bureau regulation.

Since 1997 the Labour governments of Tony Blair and Gordon Brown developed a programme of better regulation.

Since it has a low price, and good regulation, cross-flow turbines are mostly used in mini and micro hydropower units of less than two thousand kW and with heads less than 200 m.

Since then, miRNA research has revealed multiple roles in negative regulation ( transcript degradation and sequestering, translational suppression ) and possible involvement in positive regulation ( transcriptional and translational activation ).

Since then, a step-by-step process of industry reform has led to the separation of the monopoly elements from the contestable elements to create competitive markets in energy generation and electricity retailing, while imposing regulation on the natural monopolies of transmission and distribution.

Since mid 2009 there is also an € 0. 11 ( excluding tax ) maximum price for SMS text message included into this regulation.

Since self talk is a form of self regulation, parents or instructors could use this technique to help focus a young student's inner dialog towards a process goal instead of an outcome based goal.

Since the DOL has followed public notice procedure, and since there was gap left in the legislation, the DOL's regulation stands and home health care workers are not covered by either minimum wage or overtime pay requirements.

Since moment-to-moment blood pressure regulation is carried out by the sympathetic nervous system ( via the baroreceptor reflex ), calcium channel blockers allow blood pressure to be maintained more effectively than do beta blockers.

Since PKAs are present in a variety of cells and act on different substrates, PKA and cAMP regulation are involved in many different pathways.

Since there is no regulation on the rapid deforestation occurring in the Solomon Islands, limited export to recognized institutions may be needed to aid this species in genetic diversity for its survival via ex situ breeding programs.

Since Scottish Government regulation passed in 2004 mandating bus drivers to take a break every two hours, the town has become a major coach stop, as it is almost exactly two hours away from Glasgow.

Since stomata are important in water regulation, potassium reduces water loss from the leaves and increases drought tolerance.

Since then, the franking of congressional mail has been subject to ongoing review and regulation.

Since the elements can be uniquely sequenced by atomic number, conventionally from lowest to highest ( as in a periodic table ), sets of elements are sometimes specified by such notation as " through ", " beyond ", or " from ... through ", as in " through iron ", " beyond uranium ", or " from lanthanum through lutetium ".

Since cast iron was becoming cheaper and more plentiful, it also became a major structural material following the building of the innovative Iron Bridge in 1778 by Abraham Darby III.

Since the binding energy per nucleon peaks around iron, energy is only released in fusion processes occurring below this point.

Since a medieval spear required only a small amount of steel along the sharpened edges ( most of the spear-tip was wrought iron ), it was an economical weapon.

Since the core flux is proportional to the applied voltage, the iron loss can be represented by a resistance R < sub > C </ sub > in parallel with the ideal transformer.

Since the victory over France provided the Kriegsmarine with the better placed French ports on the Atlantic and the iron fields of Lorraine, Weserübung proved to be unnecessary.

Since the 19th century, iron, copper, silver, and gold have brought prosperity.

Since 1797, one group of settlements was called Königshütte ( Królewska Huta in Polish ) after the iron works.

Since northeastern Pennsylvania was a rich source of anthracite coal, anthracite-fired furnaces using locally available iron ores were built throughout eastern Pennsylvania, helping to make the state a leader in iron production in the latter half of the 19th century.

Since the magnet's iron core is conductive, and most of the magnetic field is concentrated there, eddy currents in the core are the major problem.

Since 1933, The Quality Castings Company is headquartered in Orrville and produces gray and ductile iron castings.

Since its incorporation, Sharpsburg became an industrial town, manufacturing iron, brick and glass while goods were transported through the canal that bisected the borough, along with the Allegheny River.

Since the compositions of most cast irons are around the eutectic point of the iron-carbon system, the melting temperatures closely correlate, usually ranging from, which is about lower than the melting point of pure iron.

Since carbide makes up a large fraction of the material, white cast iron could reasonably be classified as a cermet.

Since the iron was placed very close to the tip ( within 1 mm ), the motions of the tip could be tracked very accurately.

Since rusticles are found on wrought iron rather than other ferrous metals, it is supposed that the microbes also use the sulfur and phosphorus impurities found in the metal.

Since most beings from Scandinavian folklore are said to be afraid of iron, Scandinavian parents often placed an iron item such as a pair of scissors or a knife on top of an unbaptized infant's cradle.

Since 1949, Taiyuan has developed a large industrial base with heavy industry ( notably iron and steel ) of prime importance ; local coal production is considerable.

Since its construction, constant emissions of heat and caustic gases have transformed much of the rock into clays ( mostly kaolinite ), iron oxides, sulfur-rich compounds and quartz.

Since 1925, carpet-weaving, wood processing, iron smelting brick and gypsum plants were established, the Nalaikh coal mine, power plant and the leather factory in Altanbulag was expanded.

The black salsify is considered nutritious: it contains proteins, fats, asparagine, choline, laevulin, as well as minerals such as potassium, calcium, phosphorus, iron, sodium, and vitamins A, B < sub > 1 </ sub >, E and C. Since it also contains the glycoside inulin, which mainly consists of fructose, it is particularly suitable for diabetics.

Since the commercial development of this process in the Lake Superior region in the 1950s, the term taconite has been used globally to refer to iron ores amenable to upgrading by similar processes.