Sly syndrome, also called Mucopolysaccharidosis Type VII or MPS, is an autosomal recessive lysosomal storage disease characterized by a deficiency of the enzyme β-glucuronidase, a lysosomal enzyme.

Sly syndrome belongs to a group of disorders known as mucopolysaccharidoses, which are lysosomal storage diseases.

In Sly syndrome, the deficiency in β-glucuronidase leads to the accumulation of certain complex carbohydrates ( mucopolysaccharides ) in many tissues and organs of the body.

The defective gene responsible for Sly syndrome is located on chromosome 7.

The symptoms of Sly syndrome are similar to those of Hurler syndrome ( MPS I ).

* The Matthew Evangelista Foundation Inc. is a charity that is trying to raise money to find treatment for Sly syndrome.

* GUSB Beta Glucuronidase Sly syndrome

* Sly syndrome, a genetic disease

It may occur as a solitary congenital abnormality or in association with other genetic disorders or syndromes: Marfan syndrome, Ehlers Danlos Syndrome, Morquio syndrome, Noonan syndrome, Trisomy 18, Trisomy 21, homocystinuria, osteogenesis imperfecta, multiple lentigines syndrome, Sly syndrome and Scoliosis.

Deficiencies in β-glucuronidase result in the non recessive inherited metabolic disease known as Sly syndrome or Mucopolysaccharidosis VII.

He has cited acts like Marvin Gaye, Sly and the Family Stone, and Stevie Wonder as influences.

" Character names are changed, plot points are altered ( Kate has two sisters for example, not one ), the play is set in Athens instead of Padua, Sly continues to comment on events throughout the play, and entire speeches are completely different ( lines from other plays are also found in A Shrew, especially from Marlowe's Tamburlaine ), all of which suggests that the author / reporter of A Shrew thought he ( or she ) was working on something different to Shakespeare's play, not simply transcribing it.

Evidence of at least some initial societal discomfort with The Shrew is found in a contemporary alternative version that has Christopher Sly being " by his wife for dreaming here tonight " at the end of the play, suggesting that there was a market for an audience who were comfortable with the women ' winning '.

Critics have argued about the meaning of the Induction for many years, and according to Oliver, " it has become orthodoxy to claim to find in the Induction the same ' theme ' as is to be found in both the Bianca and the Katherine-Petruchio plots of the main play, and to take it for granted that identity of theme is a merit and ' justifies ' the introduction of Sly.

In 1931, Harcourt Williams used the conclusion of A Shrew ( in which, after the Petruchio / Katherina story is finished, the Lord returns the now sleeping Sly to the inn where he was found, and who, upon waking up, announces he has had a dream in which he has learned how to tame his own wife ).

Sly has been deeply moved by his dream, and the play ends with him condemning the subjugation of women and embracing his wife.

It was named after its discoverer William S. Sly ( 1932 -), an American Biochemist, in 1969 who has spent nearly his entire academic career at Saint Louis University.

Almost the whole of The Taming of the Shrew is a play-within-a-play, presented to convince Christopher Sly, a drunken tinker, that he is a nobleman watching a private performance, but the device has no relevance to the plot ( unless Katharina's subservience to her " lord " in the last scene is intended to strengthen the deception against the tinker ) and is often dropped in modern productions.

He has been cited as one of the foremost innovators of funk music, along with James Brown and Sly Stone.

Since the late 1980s, Worrell has recorded extensively with Bill Laswell, including Sly and Robbie's Laswell-produced Rhythm Killers.

In the early 1980s Sly Stone was also part of a George Clinton / Funkadelic family project with Muruga Booker called " The Soda Jerks ," who recorded an album worth of material, all of which has gone unreleased, except for one song, however Muruga has plans of still releasing the project.

Much of his work has been ignored, although a performance in 1999 of Sly by the Washington National Opera ( the work's American premiere ) marked something of a revival of interest in his works.

One of the most influential albums ever recorded, Sly & the Family Stone's There's a Riot Goin ' On ( 1971 ) has been considered among the first and best examples of the matured version of funk music, after prototypical instances of the sound in the group's earlier work.

Noddy is kind and honest, but he often gets in trouble, either through his own misunderstandings, or because someone ( usually the naughty goblins Sly and Gobbo ) has played a trick on him.

He was a member of the seminal Congolese rumba group African Jazz, and has collaborated with many other musicians, including Fania All Stars, Fela Kuti, Herbie Hancock, Bill Laswell, Bernie Worrell, Ladysmith Black Mambazo, Don Cherry, and Sly and Robbie.

* Sly Sludge has a Smog Ring ( counterpart of Wind ).

He even wrote and produced new albums for grammy-award winning singer Michael Rose of Black Uhuru, and has worked with other notable Reggae figures such as Sly Dunbar, half of one of the most influential partnerships in reggae music, Sly & Robbie.

Modern scholars reject the Shakespearean attribution ; speculation, relying on common initials, has shone on Wentworth Smith and William Sly as possible alternatives.

Abbruzzese has cited John Bonham, Sly & the Family Stone, and the Red Hot Chili Peppers as influences.

The show was highly praised for its realism and sensitivity, with a New York Times reviewer applauding the program's avoidance of stereotyping characters: " Sly, a jiving black student ... has solidly middle-class parents deeply involved in classical music " and a lower-middle-class classmate discovers that her father makes more money as a plumber than James ' professor father.

He has cited several musicians as his inspirations, including Stevie Wonder, Sly Stone, Michael Jackson, Marvin Gaye, and Donny Hathaway.

* Sly Fox Brewery ( Phoenixville, PA ) hosts an annual goat race to commemorate its bock fest.

Psychedelic soul groups like the Chambers Brothers and especially Sly and The Family Stone influenced proto-disco acts such as Isaac Hayes, Willie Hutch and the Philadelphia Sound.

" Slap style " may have influenced electric bass guitar players who, from the mid-sixties ( particularly Larry Graham of Sly and the Family Stone ), developed a technique called slap and pop that used the thumb of the plucking hand to hit the string, making a slapping sound but still letting the note ring, and the index or middle finger of the plucking hand to pull the string back so it hits the fretboard, achieving the pop sound described above.

The film uses two versions of the song " Que Sera, Sera ", the first by singer Syd Straw and another over the end credits by Sly and the Family Stone.

One of the last scenes includes Ice-T and Body Count playing with Jane's Addiction in a version of the Sly and the Family Stone song " Don't Call Me Nigger, Whitey.

Brown's recordings during this period influenced musicians across the industry, most notably groups such as Sly and the Family Stone, Funkadelic, Charles Wright & the Watts 103rd Street Rhythm Band, Booker T. & the M. G.

' Forever Changes ' unlocked a new musical palette for African American musicians to utilize, which paved the way for future song cycles like Marvin Gaye's ' What's Going On ' and Sly Stone's ' There's a Riot Going On ,' classics by other African Americans that also chronicled the increasingly despondent state of the American dream.

In some Bulgarian folk tales that originated during the Ottoman period, the name appears as an antagonist to a local wise man, named Sly Peter.

* 1970 – Tony Sly, American singer-songwriter and guitarist ( No Use for a Name and Scorpios ) ( d. 2012 )

Building on the funk sound of James Brown, it was pioneered from about 1968 by Sly and the Family Stone and The Temptations.

He also wrote the Iran-contra satire Mastergate, as well as Sly Fox and a musical adaptation of the Preston Sturges movie Hail the Conquering Hero ; during that show's troubled development Gelbart uttered the now-classic line, " If Hitler is alive, I hope he's out of town with a musical.

* For a thorough scientific overview of disorders of proline and hydroxyproline metabolism, one can consult chapter 81 of OMMBID Charles Scriver, Beaudet, A. L., Valle, D., Sly, W. S., Vogelstein, B., Childs, B., Kinzler, K. W.

During the 1960s, the city was home to an innovative funk music scene that produced well-known bands like Sly & the Family Stone, Graham Central Station, Tower of Power, Cold Blood, and The Headhunters.

Larry Graham, the bass player for both Sly & the Family Stone and Graham Central Station, is credited with the creation of the influential slap and pop sound still widely used by bassists in many musical idioms today.

His artistic influences include Sly & the Family Stone, Parliament-Funkadelic, Joni Mitchell, The Beatles, Johnny " Guitar " Watson, Miles Davis, Carlos Santana, Jimi Hendrix, James Brown, Led Zeppelin, Marvin Gaye, the Isley Brothers, Duke Ellington, Curtis Mayfield, and Stevie Wonder.

Grand Central later changed its name to Champagne and started playing original music influenced by Sly & the Family Stone, James Brown, Earth, Wind & Fire, Miles Davis, Parliament-Funkadelic, Carlos Santana, Jimi Hendrix, and Todd Rundgren.

McCrea himself cites Hank Williams, Tom Zé, the Golden Gate Quartet and Sly and the Family Stone as particular influences.

The play begins with a framing device, often referred to as the Induction, in which a mischievous nobleman tricks a drunken tinker named Sly into believing he is actually a nobleman himself.

Prior to the first act, an induction frames the play as a " kind of history " played in front of a befuddled drunkard named Christopher Sly who is tricked into believing that he is a lord.