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Page "Adherens junction" ¶ 5
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cadherins and are
Several types of cell adhesion molecules are known and one major class of these molecules are cadherins.
There are dozens of different cadherins that are expressed on different cell types.
Neighboring epithelial cells are also connected to each other through apical junctions, protein complexes containing adhesion molecules, such as cadherins, linked to catenins.
Because staining for cadherins and catenins in ingressing cells decreases and develops as intracellular accumulations, apical junctions are thought to be cleared by endocytosis during ingression.
In human cells, which have many different types of adhesion molecules, the major classes are named integrins, Ig superfamily members, cadherins, and selectins.
Cell-cell adhesions in Anchoring junctions are mediated by cadherins.
They are transmembrane proteins that bridge the space between adjacent epithelial cells by way of homophilic binding of their extracellular domains to other desmosomal cadherins on the adjacent cell.
Through the aid of specific proteins, mainly cadherins, the hemichannels are able to dock with hemichannels of adjacent cells forming gap junctions.
The cadherins are a family of homophilic CAMs, Ca < sup > 2 +</ sup >- dependent.
There are four main types: selectins, cadherins, integrins, and the immunoglobulin superfamily.
Examples are laminin or fibronectin, in the extracellular matrix, and cadherins or Ig-family cell-adhesion molecules, found on cell surfaces.
The exact means by which cadherins are linked to actin filaments is still under investigation.
In particular, abnormal interactions between epithelial cells and the extracellular matrix are associated with the over-expression of these β-catenins and their relationship with cadherins in some cancers.

cadherins and proteins
Integrins work alongside other proteins such as cadherins, immunoglobulin superfamily cell adhesion molecules, selectins and syndecans to mediate cell – cell and cell – matrix interaction and communication.
During their life cycle, connexins associate with different proteins, including ( 1 ) cytoskeletal components as microtubules, actin, and actin-binding proteins α-spectrin and drebrin, ( 2 ) junctional molecules including adherens junction components such as cadherins, α-catenin, and β-catenin, as well as tight junction components such as ZO-1 and ZO-2, ( 3 ) enzymes such as kinases and phosphatases which regulate the assembly, function, and degradation, and ( 4 ) other proteins such as caveolin.
* Aron Moscona ( Identified a class of proteins called cadherins )

cadherins and manner
Cadherins bind to other cadherins in a like-to-like manner: E-cadherin ( found on many epithelial cells ) binds preferentially to other E-cadherin molecules.

cadherins and cadherin
The cadherin superfamily includes cadherins, protocadherins, desmogleins, and desmocollins, and more.

cadherins and molecules
Cell adhesion is the binding of a cell to a surface, extracellular matrix or another cell using cell adhesion molecules such as selectins, integrins, and cadherins.

cadherins and cells
The primary mechanical role of catenins is connecting cadherins to actin filaments, specifically in these adhesion junctions of epithelial cells.

cadherins and .
Pemphigus is the result of auto-antibodies which target desmosomal cadherins.
The Outer Dense Plaque is where the cytoplasmic domains of the cadherins attach to desmoplakin via plakoglobin and plakophillin.
The non-classical cadherins Fat, Dachsous, and Flamingo appear to modulate frizzled function.
Most of the CAMs belong to four protein families: Ig ( immunoglobulin ) superfamily ( IgSF CAMs ), the integrins, the cadherins, and the selectins.
Two neural crest effectors, Rho GTPases and cadherins, function in delamination by regulating cell morphology and adhesive properties.
Beta-catenin binds the cytoplasmic domain of some cadherins.
The name " catenin " was originally selected (' catena ' means ' chain ' in Latin ) because it was suspected that catenins might link cadherins to the cytoskeleton.
Catenins play roles in cellular organization and polarity long before the development and incorporation of Wnt signaling pathways and cadherins.

are and family
and, `` I do think that families are the most beautiful things in all the world '', burst out Jo some five hundred pages later in that popular story of the March family, which had first appeared when Henrietta was eight ; ;
In their views on dating, courtship, sex, and family life, our students prefer what they are expected to prefer.
The brushes can be cleaned and sterilized by boiling and are detachable so that every member of the family can have his own.
This one was set up here in 390 A.D. on a pedestal, the faces of which are carved with statues of the emperor and his family watching games in the Hippodrome, done so realistically that the obelisk itself is included in them.
Have a test-run on the family first, to be sure timing and seasoning are right.
They come prepared for family fun because Americans in ever-growing numbers are learning that here is the way to a fine economical vacation that becomes a family experience of lasting importance.
When this experiment is viewed as composed of five binomial trials, one for each member of the family, the outcomes of the trials are obviously not independent.
Further research in the meaning of crises as experienced by the consumers of traditional social casework services -- including attempts to develop a typology of family structures, crisis problems, reaction mechanisms, and differential treatment approaches -- and the establishment of new experimental programs are imperative social needs which should command the best efforts of caseworkers in collaboration with community planners.
`` Very few wives '', says Dr. Calderone, `` who balance the checkbook, fix the car, choose where the family will live and deal with the tradesmen, are suddenly going to become submissive where sex is concerned.
If you are not well acquainted with the area in which you wish to locate, or if you are not sure that you and your family will like and make a success of farming, usually you would do better to rent a place for a year or two before you buy.
These are substantially the same factors considered by Non-Catholics in family planning.
Catholics, Protestants and Jews are in agreement over the objectives of family planning, but disagree over the methods to be used.
These, he said, are `` two of the principal underlying causes for family breakups leading to ADC ''.
To outsiders, the Blacks seem to be an ordinary, happy family, and they are -- but with a difference.
As only a member of the family can share in the innermost joys of the family, likewise one must belong to the family of God in order to receive the benefits that are promised to those who are His own.
You may know that you are in God's family and be just as sure of it as you are that you belong to the family of your earthly father.

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