In particular, the successful entrapment of Graham Riddick and David Tredinnick in the " cash for questions " scandal, the contemporaneous misconduct as ministers by Neil Hamilton ( who lost a consequent libel action against The Guardian ), Tim Smith, and the convictions of former Cabinet member Jonathan Aitken and former party deputy chairman Jeffrey Archer for perjury in two separate cases leading to custodial sentences damaged the Conservatives ' public reputation.

This incident long damaged the army's reputation, leading to persistent calls for its abolition among left-wing politicians.

Multiple sclerosis ( MS ), also known as " disseminated sclerosis " or " encephalomyelitis disseminata ", is an inflammatory disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading to demyelination and scarring as well as a broad spectrum of signs and symptoms.

This damage impairs the ability of some nerve receptors in the spine to properly receive gamma amino butyric acid, leading to hypertonia in the muscles signaled by those damaged nerves.

In transit, the gremlin damaged the sphere, causing Frank Parker to " lose the needles " for the very first time, leading to his first failed Backstep.

The clinical underpinnings of two of the most common spasticity conditions, spastic diplegia and multiple sclerosis, can be described as follows: in spastic diplegia, the upper motor neuron lesion arises often as a result of neonatal asphyxia, while in conditions like multiple sclerosis, spasticity is thought by some to be as a result of the autoimmune destruction of the myelin sheaths around nerve endings — which in turn can mimic the gamma amino butyric acid deficiencies present in the damaged nerves of spastic diplegics, leading to roughly the same presentation of spasticity, but which clinically is fundamentally different from the latter.

These complaints damaged the king's standing within the Council leading to criticism of his ability to curb Buchan's activities.

The cause of the accident was determined to be a piece of foam that broke off during launch and damaged the thermal protection system components ( reinforced carbon-carbon panels and thermal protection tiles ) on the leading edge of the left wing of the Shuttle orbiter, causing an extensive heat build-up.

During re-entry the damaged wing slowly overheated and came apart, eventually leading to loss of control and total disintegration of the vehicle.

* Angle recession glaucoma, a disease in which the optic nerve is damaged, leading to progressive, irreversible loss of vision

Recoilless rifles are maintenance-intensive weapons, and if the breech and gas ports are old, damaged, plugged or poorly maintained, the recoil-damping effect can be reduced or lost altogether, leading to dangerously powerful recoil.

Swelling of the damaged muscle occasionally leads to compartment syndrome — compression of surrounding tissues, such as nerves and blood vessels, in the same fascial compartment — leading to the loss of blood supply and damage or loss of function in the part ( s ) of the body supplied by these structures.

There are other exceptions in which SRY is damaged ( leading to an XY female ), or copied to the X ( leading to an XX male ).

He finished his active fighter career in 1941 with 27 kills destroyed, 7 shared destroyed and 2 unconfirmed, 3 probables and 16 damaged, at the time the RAF's leading ace, and one of the highest scoring pilots to have served wholly with Fighter Command during World War II.

Occasionally, the amount of air in the chest increases markedly when a one-way valve is formed by an area of damaged tissue, leading to a tension pneumothorax.

These are adrenal dysgenesis ( the gland has not formed adequately during development ), impaired steroidogenesis ( the gland is present but is biochemically unable to produce cortisol ) or adrenal destruction ( disease processes leading to the gland being damaged ).

* Locomotive 911 was seriously damaged by fire at the Wilmington, DE station on April 26, 2011 while leading the Silver Star northbound and then retired.

* Acting in accordance with Earth Force regulations ( General Order # 47 ), Sheridan offers sanctuary to a damaged Narn ship, leading to an armed confrontation with a Centauri battlecruiser.

Some studies suggest that hypoxia resulting from inadequate perfusion upregulates sFlt-1, a VEGF and PlGF antagonist, leading to a damaged maternal endothelium and restriction of placental growth.

The most significant finding of the scientific team was a line of damaged trees broken at the top leading to the site where some eyewitnesses said they saw the object embedded in the soil along with associated fresh tree damage.

This was most likely due to the attempt to mass-produce something that was barely understood, leading to damaged phages in the product, or to insufficient amounts thereof.

This places greater stress on the remaining insulation, leading to further growth of the damaged region, resistive heating along the tree, and further charring ( sometimes called tracking ).

The party, however, damaged its credibility through a series of high-profile policy reversals in the period leading up to the election.

If histone acetyltransferases are inhibited, then damaged DNA may not be repaired, eventually leading to cell death.

When D < sup > G </ sup > 791 was found to have a cracked bogie bolster in the early 1990s, one from the remains of DG 2376 was used to replace the damaged assembly ( trains were kept running by the use of D < sup > G </ sup > 772 from the Diesel Traction Group at Ferrymead ).

Due to the overall string voltage depletion due to the dead cells, the charging system may detect this as a state of discharge, and will continuously attempt to charge the series-parallel strings, which leads to continuous overcharging and damage to all the cells in the degraded series string containing the damaged battery.

When the cathedral begun in 1137 was ready for consecration the relics of St Magnus were transferred, and in 1917 a hidden cavity was found in a column, containing a box with bones including a damaged skull.

Youthdale also claimed their reputation was damaged as a result of various actions by the named defendants, which Youthdale alleged included the creation of websites and blogs containing complaints against Youthdale, including alleged accusations of unlawful administration of psychotropic medications.

Fluids that would be damaged by heat ( such as those containing proteins like large molecule drug products, but also wine and beer ) irradiation or chemical sterilization, can be only sterilized by Microfiltration using membrane filters.

A 2011 study by the Population Council found that many commercially-available water-based sexual lubricants tested damaged human rectal cells and that some of them-those containing polyquaternium-15-appeared to actively increase HIV replication in cell cultures and therefore could raise one's risk of HIV transmission.

That wooden statue was damaged by a storm in 1248, and the hall containing it was destroyed, so Jōkō suggested making another statue of bronze, and the huge amount of money necessary for this and for a new hall was raised for the project.

Similarly, some containers containing toxic fire retardant, flammable ink and paint and Sodium Persulphate were affected, and several containers were damaged or destroyed during the incident, ejecting other goods into the bay.

It consists of application software running under the operating system, and a USB or PCI card containing software to bootstrap the computer and to restore damaged files.

In late 2009, a badly damaged home video recording was recovered by the British Film Institute containing two of the shows the song was performed on, though only the first appearance was recoverable in part.

In 2001, a 9 km tunnel from Penrose to Hobson Street via Liverpool Street was completed, containing two new 110 kV cables to replace the damaged Liverpool Street cables and the temporary overhead line.

However, Leigh has a box sent to him containing a damaged videotape reel, which Leigh assumes is tape from the Fact or Fiction team thought not to exist.

However, like willows, poplars have very vigorous and invasive root systems stretching up to 40 m from the trees ; planting close to houses or ceramic water pipes may result in damaged foundations and cracked walls and pipes due to their search for moisture.

Other claims regarding the crack in the bell include stories that it was damaged while welcoming Lafayette on his return to the United States in 1824, that it cracked announcing the passing of the British Catholic Relief Act 1829, and that some boys had been invited to ring the bell, and inadvertently damaged it.

He was knocked unconscious, had severe lacerations to his face and head ( needing over 100 stitches ), had three fractures to his skull, cracked ribs, damaged jaw, teeth, kidneys and damage to his back and spine ( these plagued him through the rest of his life ).

Several walls are cracked and parts are clearly damaged, most notably the right-hand door post of the north side gate.

The quake damaged virtually all buildings in Charleston, creating sand volcanoes by the city, cracked a pier on the Cairo Rail Bridge and toppled chimneys in St. Louis, Missouri, Memphis, Tennessee, Gadsden, Alabama and Evansville, Indiana.

Initial reports indicate that the Yuzui Levee was cracked but not severely damaged.

By June 11 he had decided to retire by September of that year, as his wrestling style had begun resulting in a number of nagging injuries, including two herniated discs, damaged knees, a damaged right shoulder and a jaw cracked to the point of not even being able to eat hard food.

Severely cracked or damaged pieces were partially removed and a report was written from these findings.

The bell cracked due to a fire in 1802 and after repair in 1848 was damaged again.