It is like a mysterious epidemic which, starting first with Abigail and Parris, spreads inexorably with a dreadfully growing virulence through the whole town until all have been infected by it.

In his first sermon, given during the first month of the plague, Paneloux describes the epidemic as the " flail of God ," through which God separates the wheat from the chaff, the good from the evil.

As the numbers of settlers from the mainland increased ( at first mostly prisoners and involuntary indentured labourers, later purposely recruited farmers ), these indigenous people lost territory and numbers in the face of punitive expeditions by British troops, land encroachment and the effects of various epidemic diseases.

Hippocrates introduced the Hippocratic Oath for physicians, which is still relevant and in use today, and was the first to categorize illnesses as acute, chronic, endemic and epidemic, and use terms such as, " exacerbation, relapse, resolution, crisis, paroxysm, peak, and convalescence ".

) The first act was called for, owing to an alarm, lest plague should be imported from Poland and the Baltics ; the second act of 1721 was due to the disastrous prevalence of plague at Marseille and other places in Provence, France ; it was renewed in 1733 owing to a fresh outbreak of the malady on the continent of Europe, and again in 1743, owing to the disastrous epidemic at Messina.

An epizootic ( animal disease epidemic ) of RVF is usually first indicated by a wave of unexplained abortions.

In the first incident, approximately one fifth of the Samoan population died in the influenza epidemic of 1918-1919.

Mallon was the first apparently perfectly healthy person known to be responsible for an " epidemic ".

There was no catastrophic epidemic or famine in England or Scotland in the 19th century – it was the first century in which a major epidemic did not occur throughout the whole country, with deaths per 1000 of population per year in England and Wales dropping from 21. 9 from 1848 – 54 to 17 in 1901 ( contrasting with, for instance, 5. 4 in 1971 ).

It has been said that the comic books and the X-Men animated series delved into the AIDS epidemic with a long-running plot line about the Legacy Virus, a seemingly incurable disease thought at first to attack only mutants ( similar to the AIDS virus which at first was spread through the gay community ).

The first written account of the disease dates to 1495 when an epidemic struck the island of Hispaniola.

In 1685 Brazil experienced its first epidemic, in Recife.

Because of this, epidemic or pandemic diseases, which depend on a constant influx of humans who have not developed an immune response, tended to burn out after their first run through a population.

* Sedentary lifestyles, due to labor-saving devices and technology, contributed to an " epidemic " of obesity, at first in the rich countries, but by the end of the century, increasingly in the developing world, too.

* 1507: The first recorded epidemic of smallpox in the New World occurs on the island of Hispaniola and decimates the native Taíno population.

According to historian Alfred W. Crosby Jr. in his The Columbian Exchange: Biological and Cultural Consequences of 1492, this outbreak is the first widely documented epidemic in the New World.

Brill-Zinsser disease, first described by Nathan Brill in 1913 at Mount Sinai Hospital in New York City, is a mild form of epidemic typhus which recurs in someone after a long period of latency ( similar to the relationship between chickenpox and shingles ).

The first epidemic was an unknown sickness occurring sometime between 1564 and 1570, and the second one was typhus in 1586.

Stimulated by a severe epidemic, variolation was first employed in North America in 1721.

In 1919, the Spanish influenza epidemic forced the Montreal Canadiens and the Seattle Metropolitans to cancel their series, marking the first time the Stanley Cup was not awarded.

The term epidemic derives from a term first attributed to Homer's Odyssey, which later took its medical meaning from a treatise by Hippocrates, Epidemics.

The distinction between " epidemic " and " endemic " was first drawn by Hippocrates, to distinguish between diseases that are " visited upon " a population ( epidemic ) from those that " reside within " a population ( endemic ).

He realizes after the first few cases that the disease is bubonic plague and is aware of the seriousness of the situation.

The Plague of Justinian in the 6th and 7th centuries is the first known attack on record, and marks the first firmly recorded pattern of bubonic plague.

Waldemar Haffkine, a doctor who worked in Bombay, India, was the first to invent and test a plague vaccine against bubonic plague in 1897.

It happened within the centuries-long time period of the Second Pandemic, an extended period of intermittent bubonic plague epidemics which began in Europe in 1347, the first year of the " Black Death " and lasted until 1750.

* Plague of Justinian, from 541 to 750, was the first recorded outbreak of the bubonic plague.

This group of Nothelfer (" helpers in need ") originated in the 14th century at first in the Rhineland, largely as a result of the epidemic ( probably of bubonic plague ) that became known as the Black Death.

The Oberammergau Passion Play was first performed in 1634 and is the result of a vow made by the inhabitants of the village that if God spared them from the effects of the bubonic plague then sweeping the region they would perform a passion play every ten years.

The Service first became involved in the situation in 1900 when MHS physician Joseph J. Kinyoun, stationed in San Francisco, confirmed by bacteriological analysis that the death of a laborer in the city's Chinatown section was due to bubonic plague.

His first assignment involved fieldwork on bubonic plague in New Orleans.

He is recognized as the first microbiologist who developed and used vaccines against cholera and bubonic plague.

He also took part in the development in the first immune serum against the bubonic plague ( black pest ), in collaboration with the discoverer of its pathogenic agent, Yersinia pestis, by Alexandre Yersin ( 1863 – 1943 ), and went to Portugal to study and to help fight an epidemic at Oporto.

The first was primarily bubonic and was carried around the world through ocean-going trade, through transporting infected persons, rats, and cargoes harboring fleas.

During the year there happened the first great destruction of the community of the inhabitants caused by bubonic plague disease.

In " The Ratman " ( March 7, 1959 ) on NBC's Cimarron City, Sloane plays a brilliant German-born physician, Hans J. Eckhardt, who tries to alert the town to the danger of bubonic plague, which he had first detected on a nearby riverboat.

An old man, he is the first victim of the plague.

When he contracts the plague, he is the first to receive Dr. Castel's anti-plague serum.

During the first stage of the plague outbreak, Paneloux preaches a sermon at the cathedral.

* The Prefect: The Prefect believes at first that the talk of plague is a false alarm, but on the advice of his medical association, he authorizes limited measures to combat it.

It is Rieux who treats the first victim of plague and who first uses the word plague to describe the disease.

He also keeps a diary, full of his observations of life in Oran, which Rieux incorporates into the narrative .</ br > It is Tarrou who first comes up with the idea of organizing teams of volunteers to fight the plague.

However, according to George Sussman, the first obvious medical description of plague in China dates to 1644.

It is mainly a disease in the fleas ( Xenopsylla cheopis ) that infested the rats, making the rats themselves the first victims of the plague.

People who die from this form of plague often die on the same day symptoms first appear.

The dock areas outside of London and the parish of St Giles in the Fields, where poor workers crowded into ill-kept structures, were the first areas struck by the plague.

Intimate knowledge of some events in the first years of the Peloponnesian War ( VI, 91 ; VII, 133, 233 ; IX, 73 ) indicate that he might have returned to Athens, in which case it is possible that he died there during an outbreak of the plague.

The first one was the plague, which lasted from 541 to 543 and, by decimating the Empire's population, probably created a scarcity of labor and a rising of wages.

It was the first of a cycle of European plague epidemics that continued until the 18th century.