A number of unique medical problems might be created when man is exposed to an infectious agent through the respiratory route rather than by natural portal of entry.

The inner orbital route runs approximately around the heart of the Georgian city and the outer orbital route runs primarily along the natural circle formed by Dublin's two canals, the Grand Canal and the Royal Canal, as well as the North and South Circular Roads.

The Sulaiman Mountains dominate the northeast corner and the Bolan Pass is a natural route into Afghanistan towards Kandahar.

A very natural restriction of the TSP is to require that the distances between cities form a metric, i. e., they satisfy the triangle inequality, that is the direct connection from A to B is never longer than the route via intermediate C:

The length of the minimum spanning tree of the network is a natural lower bound for the length of the optimal route, because deleting any edge of the optimal route yields a Hamiltonian path, which is a spanning tree in.

Some trails are designated as educational trails which are specially laid-out paths that offer information on specific natural, technological or cultural themes at various stations en route, usually by means of information boards and / or exhibits.

Judging by a map it might appear to follow a meandering path across the moor, but the route was carefully selected by skilled engineers, who followed the natural contours of the land.

In June 2007, Eni and Gazprom disclosed the South Stream project whereby a-long offshore natural gas pipeline from Russia's Dzhubga with annual capacity of 63 billion cubic meters is planned to come ashore at Varna, possibly near the Galata offshore gas field, en route to Italy and Austria.

Knoxville, Georgia was established on the Federal Wire Road, the main stagecoach and telegraph route from Washington, D. C., to New Orleans, making the town a natural choice for county seat.

They did confirm, however, that it was possible to travel easily from the Great Lakes all the way to the Gulf of Mexico by water, that the native peoples who lived along the route were generally friendly, and that the natural resources of the lands in between were extraordinary.

The natural route from Fort Kaskaskia to Fort Vincennes would start by following the Kaskaskia / Big Muddy divide to Kell.

The natural route would start east out of Fort Kaskaskia, climbing to the Kaskaskia / Big Muddy divide, somewhere near modern Sparta, Illinois.

Beyond Kell there was no natural route along divides to Fort Vincennes: it would involve a detour of more than to avoid major river crossings.

Duncan lies on the natural overland route across Nebraska running up the Platte and the Loup valleys, and transportation has always been a major factor in its history.

This exploited Bordentown's natural location as the point on the Delaware River that provided the shortest overland route to Perth Amboy, from which cargo and people could be ferried to New York City.

Among the lands granted the monks was a natural salt evaporation pond a short way up the river, a site also crossed by the important via regia trade route.

A natural ten feet drop in elevation in a narrow neck between the two streams provided an excellent route for millraces and water-powered grist and saw mills were soon in operation.

These were lined up to be as straight as possible, only deviating from their path due to natural obstacles that prevented a direct route.

Indeed, enjoyment of the natural surroundings of the walk is the primary motivating factor for many people following the route.

The ancient but natural transport route for Aylsham would have been the River Bure, but it was not open to substantial navigation.

The canal was part of a larger scheme for the construction of a secure inland canal route from London to Portsmouth, which allowed craft to move between the two without having to venture into the English Channel and possibly encounter enemy ships or natural disaster.

The city itself was located among abundant fertile upland soils, and may have dominated a natural east — west trade route across the Yucatan Peninsula.

The volcano is part of the natural UNESCO World Heritage Site Volcanoes of Kamchatka.

Other popular natural destinations include Kamchatka with its volcanoes and geysers, Karelia with its many lakes and granite rocks, Altai with its snowy mountains and Tyva with its wild steppes.

( Image: Stereogram guide cross-eyed. png | 10px ) Lake Palanskoye in northern Kamchatka Peninsula was formed when a large landslide disrupted the drainage pattern, forming a natural dam.

It was simply a matter of curiosity, a natural right to examine.

Thirty years ago, while the nation was wallowing in economic depression, the prevailing philosophy of government was to stand aside and allow `` natural forces '' to operate and cure the distress.

William Gilmore Simms, sturdy realist that he was, pleaded for a natural robustness such as he found in his favorites the great Elizabethans, to vivify the pale writings being produced around him.

The obvious natural fact to ancient thinkers was the diurnal rotation of the heavens.

I fled, however, not from what might have been the natural fear of being unable to disguise from you that the things about my bridegroom -- in the sense you meant the word `` things '' -- which you had been galvanizing yourself to tell me as a painful part of your maternal duty were things which I had already insisted upon finding out for myself ( despite, I may now say, the unspeakable awkwardness of making the discovery on principle, yes, on principle, and in cold blood ) because I was resolved, as a modern woman, not to be a mollycoddle waiting for Life but to seize Life by the throat.

As was only natural he confided his searchings to Ann, conceding ruefully that it certainly looked as if their own Congregationalists were wrong and the Baptists right.

As the field on which my tent was pitched was a favorite natural playground for the kids of the neighborhood, I had made many friends among them, taking part in their after-school games and trying desperately to translate Grimm's Fairy Tales into an understandable French as we gathered around the fire in front of the tent.

The Acropolis had been scheduled for the treatment too, but apparently it was to take place at the time of the full moon when the Athenians themselves, out of respect for the natural beauty of the occasion, were wont to forgo their own usual nocturnal illumination.

His father was a professor at Hartford Theological Seminary, and from him he acquired a conviction, which he passed along to me, that there is in the universe of persons a moral law, the law of love, which is a natural law in the same sense as is the physical law.

To the pope, head of the universal Church, to the duke of Burgundy, taking full advantage of his position on the borders of France and of the Empire, or to Othon, who found it quite natural that he should do homage to Edward for Tipperary and to the count of Savoy for Grandson, Flotte's outspoken nationalism was completely incomprehensible.

The poet was by definition a realist, his imaginings and parables being natural organizations of reality.

Milton was required to absorb and display an intensive and accurate knowledge of Latin grammar, logic-rhetoric, ethics, physics or natural philosophy, metaphysics, and Latin, Greek, and Hebrew.

`` I had natural sock '', he says, ' as a storyteller and was precociously good at description, dialogue, and most of the other staples of the fiction-writer's trade but I was bugged by a mammoth complex of thoughts and feelings that prevented me from doing more than just diddling the surface of sustained fiction-writing ''.

The medical examiner states that death was due to `` natural causes ''.

In the earlier sessions there was plentiful discussion on the natural law, which Dr. William V. O'Brien of Georgetown University, advanced as the basis for widely acceptable ethical judgments on foreign policy.

The impression was unmistakable that, whatever one may choose to call it, natural law is a functioning generality with a certain objective existence.

It was only natural that Fletcher would strive for a position in which he could make the decisions.

Out of this background of hunting and fishing, it was only natural that Roy first painted subjects he knew best: hunters in the field, fishermen in the stream, ducks and geese on the wing -- almost always against a vast backdrop of weather landscape.

Finally, the conception of the natural community of all possessions which originated with the Stoics was firmly fixed in a tradition by More's time, although it was not accepted by all the theologian-philosophers of the Middle Ages.

As American artists, it was natural that we would want to meet as many Soviet artists as possible.

And in the dark days after the Great Flood of 1927 -- the worst natural disaster in the state's history -- the little plane was its sole replacement in carrying the United States mails.