A number of unique medical problems might be created when man is exposed to an infectious agent through the respiratory route rather than by natural portal of entry.

The inner orbital route runs approximately around the heart of the Georgian city and the outer orbital route runs primarily along the natural circle formed by Dublin's two canals, the Grand Canal and the Royal Canal, as well as the North and South Circular Roads.

The Sulaiman Mountains dominate the northeast corner and the Bolan Pass is a natural route into Afghanistan towards Kandahar.

A very natural restriction of the TSP is to require that the distances between cities form a metric, i. e., they satisfy the triangle inequality, that is the direct connection from A to B is never longer than the route via intermediate C:

The length of the minimum spanning tree of the network is a natural lower bound for the length of the optimal route, because deleting any edge of the optimal route yields a Hamiltonian path, which is a spanning tree in.

The natural route to Kamchatka was along tributaries of the Lena ; but after the Treaty of Nerchinsk ( 1689 ) this looked politically infeasible.

Some trails are designated as educational trails which are specially laid-out paths that offer information on specific natural, technological or cultural themes at various stations en route, usually by means of information boards and / or exhibits.

Judging by a map it might appear to follow a meandering path across the moor, but the route was carefully selected by skilled engineers, who followed the natural contours of the land.

In June 2007, Eni and Gazprom disclosed the South Stream project whereby a-long offshore natural gas pipeline from Russia's Dzhubga with annual capacity of 63 billion cubic meters is planned to come ashore at Varna, possibly near the Galata offshore gas field, en route to Italy and Austria.

Knoxville, Georgia was established on the Federal Wire Road, the main stagecoach and telegraph route from Washington, D. C., to New Orleans, making the town a natural choice for county seat.

They did confirm, however, that it was possible to travel easily from the Great Lakes all the way to the Gulf of Mexico by water, that the native peoples who lived along the route were generally friendly, and that the natural resources of the lands in between were extraordinary.

The natural route from Fort Kaskaskia to Fort Vincennes would start by following the Kaskaskia / Big Muddy divide to Kell.

Beyond Kell there was no natural route along divides to Fort Vincennes: it would involve a detour of more than to avoid major river crossings.

Duncan lies on the natural overland route across Nebraska running up the Platte and the Loup valleys, and transportation has always been a major factor in its history.

This exploited Bordentown's natural location as the point on the Delaware River that provided the shortest overland route to Perth Amboy, from which cargo and people could be ferried to New York City.

Among the lands granted the monks was a natural salt evaporation pond a short way up the river, a site also crossed by the important via regia trade route.

A natural ten feet drop in elevation in a narrow neck between the two streams provided an excellent route for millraces and water-powered grist and saw mills were soon in operation.

These were lined up to be as straight as possible, only deviating from their path due to natural obstacles that prevented a direct route.

Indeed, enjoyment of the natural surroundings of the walk is the primary motivating factor for many people following the route.

The ancient but natural transport route for Aylsham would have been the River Bure, but it was not open to substantial navigation.

The canal was part of a larger scheme for the construction of a secure inland canal route from London to Portsmouth, which allowed craft to move between the two without having to venture into the English Channel and possibly encounter enemy ships or natural disaster.

The city itself was located among abundant fertile upland soils, and may have dominated a natural east — west trade route across the Yucatan Peninsula.

After the seventeenth century the audience ceased to be an organic community to which these ideas and their attendant habits of figurative language would be natural or immediately familiar.

It was only natural that Fletcher would strive for a position in which he could make the decisions.

The effect of the recording is very open and natural, with the frequency emphasis exactly what you would expect from a live performance.

As American artists, it was natural that we would want to meet as many Soviet artists as possible.

Such mannerisms would be less worthy of remark, were it not that in Great Expectations, as in no other of Dickens' novels, hands serve as a leitmotif of plot and theme -- a kind of unifying symbol or natural metaphor for the book's complex of human interrelationships and the values and attitudes that motivate them.

`` Don't forget, there was the hope it would pass for a natural death '', Pauling reminded him.

Their demand against the Calvinist Orthodoxy for intellectual liberty had never meant that they would follow `` free inquiry '' to the extreme of proclaiming Christianity a `` natural '' religion.

Hope for the future would lie in the natural longing of the human race for freedom and the right to develop ''.

Just the evocations of time and place, of passionate encounter between man and a natural world which today seems almost lost, would be enough.

The Angels in turn would exercise similar restraints in respect for the natural preferences and natures of the Earthmen -- but they had no faintest notion of man's perverse habit of passing and enforcing laws which were contrary to his own preferences and violations of his nature.

( A formal proof for all finite sets would use the principle of mathematical induction to prove " for every natural number k, every family of k nonempty sets has a choice function.

Lincoln believed that slavery would die a natural death if contained

He never gets home until late, and he has to distance himself from the natural pity that he feels for the victims ; otherwise, he would not be able to go on.

However, since Paul was from Cilicia and refers to himself using this name ( see Acts 21: 39, 22: 3 ), it seems very natural that the name Cilicia would have continued to be in colloquial use among its residents despite its hiatus in official Roman nomenclature.

Terrain would ideally be flat, firm, unobstructed by natural barriers or fortifications, and interspersed with roads and railways.

Because of continued pressure on space the decision was taken to move natural history to a new building in South Kensington, which would later become the British Museum of Natural History.

The concept of zero ( which was also called " cipher "), which we all now think of as natural, was alien to medieval Europe, so confusing and ambiguous to common Europeans that in arguments people would say " talk clearly and not so far fetched as a cipher ".

Typical of his satire and cynical humour, the book included a discourse on Parkinson's Law of Triviality ( debates about expenses for a nuclear plant, a bicycle shed, and refreshments ), a note on why driving on the left side of the road ( see road transport ) is natural, and suggested that the Royal Navy would eventually have more admirals than ships.

According to one historical account, aboriginal tribes of Australia were " most certainly cannibals ", and would willingly eat anyone who was killed in a fight ; they would also eat men famed for their fighting ability who had died natural deaths "... out of pity and consideration for the body ".

The colony, a mere source of natural resources, would finally begin to develop as a nation.

If a 12 is rolled, it is a push ( this is to reverse the natural house advantage: because the don't come bet puts the player in the position of the house, it would otherwise favour the player ).

Aristotle, ( 384 – 322 BCE ), believed earth was the heaviest element, and his theory of natural place suggested that any earth – laden substances, would fall quickly, straight down, toward the center of the cosmos.

Traditionally, within the toad's natural range in South America, the Embera-Wounaan would " milk " the toads for their toxin, which was then employed as an arrow poison.

Guest and Levy write backgrounds for each of the characters and notecards for each specific scene, outlining the plot, and then leave it up to the actors to improvise the dialogue, which is supposed to result in a much more natural conversation than scripted dialogue would.