Bioinformaticians continue to produce specialized automated systems to manage the sheer volume of sequence data produced, and they create new algorithms and software to compare the sequencing results to the growing collection of human genome sequences and germline polymorphisms.

From 1900, the Pathé company films also frequently copied and varied the ideas of the British film-makers, without making any major innovations in narrative film construction, but eventually the sheer volume of their production led to their film-makers giving a further precision and polish to the details of film continuity.

His output in every field during his long life was prodigious ; when the sheer volume of correspondence, sketches, and reminiscences that survive is also taken into account, he is the best-documented artist of the 16th century.

Although a contraption at Stephansplatz in Hamburg is now thought to have predated them by two years, it has often been stated that the first traffic lights in Continental Europe were erected at Potsdamer Platz on 20 October 1924, in an attempt to control the sheer volume of traffic passing through.

ASL also sets the record for sheer volume of playing components, with thousands of official counters and 60 + " geomorphic mapboards " not counting Deluxe and Historical maps.

Due to the sheer volume and speed of air movement required, the fans may be powered by stationary turbofan engines rather than electric motors.

Upon the confirmation of Putnam to his appointed duty of Librarian of Congress, one daunting task Putnam faced from the onset was the sheer volume of materials that had to be reorganized for the newly opened Thomas Jefferson Building – the newly appointed library for the Library of Congress.

It damaged my hearing permanently, and today I've still got a hearing problem because of the sheer volume throughout the last year of Cream.

File: Nanjing_1937_self-organized_burial_team. jpg | The sheer volume of murdered civilians posed a formidable logistical challenge when it came to disposing of the bodies.

In sheer volume, Avsenik's compositions rank him with Slovenian folk music, Matt Hoyer, and Dr. William J.

Ilúvatar then proposes a Third Theme that Melkor attempts to corrupt through sheer force of volume of his own, but the power of the Third Theme is in the very subtlety that Melkor's lacks, and thus he never succeeds.

As the volume, sheer numbers, and intensity of the crowds build, the Walkers become more hostile and paranoid.

The sheer volume of recorded performances would undoubtedly yield some definitive performances from a very capable and rather forward-looking conductor.

The sheer volume of firsthand testimony and primary documentation that Solzhenitsyn managed to assemble in The Gulag Archipelago made all subsequent Soviet and KGB attempts to discredit the work useless.

However, repeated violations of the rules sometimes turned some of the counselors apathetic ; without choice, they often had to turn a blind eye to inappropriate minor misdeeds as the sheer volume of these violations became simply unmanageable.

The primary mechanism this interdependence is the sheer volume of lipid material involved.

As ambush hunters they will sit and wait for prey, but tend to graze their area as well, making them bloated by the sheer volume of food taken in.

While most philosophers fail to achieve much of a following outside the academy of their professional peers, by the 1870s and 1880s Spencer had achieved an unparalleled popularity, as the sheer volume of his sales indicate.

" By distilling the complex models, theories, rhetorical style and sheer volume of the Buddha's teachings into concise, crystalline verses, the Dhammapada makes the Buddhist way of life available to anyone ... In fact, it is possible that the very source of the Dhammapada in the third century B. C. E.

The sheer volume of hard liquor consumption fell off, but beer grew in popularity and men developed customs and traditions based on how to behave at the tavern.

On August 19, Sobig. F became known and set a record in sheer volume of e-mails.

To compensate it was simpler to concentrate the fire of several vehicles onto the target, sacrificing accuracy for sheer volume of firepower.

In terms of sheer volume, Oh Yeah!

The sheer volume of book-titles, pictures and objects listed in Musaeum Clausum is testimony to Browne's fertile imagination ; however his major editors, Simon Wilkins in the nineteenth century ( 1834 ) and Sir Geoffrey Keynes in the twentieth ( 1924 ) summarily dismissed it.

" T. Coraghessan Boyle of The New York Times Book Review wrote, " This is old Pynchon, the true Pynchon, the best Pynchon of all, Mason & Dixon is a groundbreaking book, a book of heart and fire and genius, and there is nothing quite like it in our literature ," New York Times critic Michiko Kakutani said, " A novel that is as moving as it is cerebral, as poignant as it is daring ... a book that testifies to Pynchon's remarkable powers of invention and his sheer power as a storyteller.

Taking both languages together until the end of the nineteenth century, and taking into account all the monastic documents, literature in the widest sense of the term, and texts in " near-Chinese " ( hentai-kanbun ), it is entirely possible that the sheer volume of texts written in Chinese in Japan slightly exceed what was written in Japanese.

Although the college game has a much larger margin for talent than its pro counterpart, the sheer number of fans following major colleges provides a financial equalizer for the game, with Division I programs – the highest level – playing in huge stadiums, six of which have seating capacity exceeding 100, 000.

Discharging both barrels at the same time has long been a hunting trick employed by hunters using 8 gauge " elephant " shotguns, firing the two two-ounce slugs for sheer stopping power at close range.

Polish director, Wojciech Has, whose two major films, The Saragossa Manuscript ( 1965 ) and The Hour-Glass Sanatorium ( 1973 ) are examples of modernist fantasies, has been compared to Fellini for the sheer " luxuriance of his images ".

Though Australia has a small population, the sheer number of venues that bands could play in, mainly along the Eastern coast, meant that a band could tour extensively, often playing every night for long periods.

The sheer bulk of online quotations, combined with more efficient search engines, has effectively made the Internet the world's quotation storehouse, encompassing an unprecedented number of easily obtainable quotations.

Above all, her words are chosen for their sheer melody: the skill with which she placed her vowels and consonants, admired by Dionysius of Halicarnassus, is evidenced by almost any stanza ; the music to which she sang them has gone, but the spoken sounds may still enchant.

In modern mechanised societies, there is less need for sheer massive manpower ; Norbert Wiener wrote that " mechanical labor has most of the economic properties of slave labor, though ... it does not involve the direct demoralizing effects of human cruelty.

Owing to the size and sheer cost of production, Cavalcade has not been staged in anything remotely like its original form ever since its initial production.

Similarly, Greater Tokyo, through its 20 year recession, has managed to outpace the growth of all other cities in Japan of a million people or more by its sheer concentration of economic, infrastructure, and people power.

John Derbyshire, who says he has " complicated and sometimes self-contradictory feelings about Jews ", wrote on National Review Online regarding what he saw as the Jewish overreaction to the article that " It was a display of arrogance, cruelty, ignorance, stupidity, and sheer bad manners by rich and powerful people towards a harmless, helpless young writer, and the Jews who whipped up this preposterous storm should all be thoroughly ashamed of themselves ".

There is another kind of vibrato-linked fault that can afflict the voices of operatic artists, especially aging ones — namely the slow, often irregular wobble produced when the singer's vibrato has loosened from the effects of forcing, over-parting, or the sheer wear and tear on the body caused by the stresses of a long stage career.

The ability of geckos – which can hang on a glass surface using only one toe – to climb on sheer surfaces has been attributed to the van der Waals forces between these surfaces and the spatula ( plural spatulae ), or microscopic projections, which cover the hair-like setae found on their footpads.

The concept of matching animation to classical music was used as early as 1928 in Disney's cartoon series, the Silly Symphonies, but he wanted to go beyond the usual slapstick, and produce shorts where " sheer fantasy unfolds ... action controlled by a musical pattern has great charm in the realm of unreality.

Attesting to the sheer size of this shell is the famous first sentence of the shell's manual page, which reads " Because zsh contains many features, the zsh manual has been split into a number of sections ", and then goes on to list seventeen items.

This 3, 143-foot peak, located between Helen and Cleveland, is dramatically rimmed by sheer cliffs and has the distinction of being the highest point on Georgia's Piedmont Plateau.

Although regarded as a dashing, compelling actor as well, Tibbett's true fame stems from the fact that he has long been considered to be, in terms of sheer voice, one of the finest baritones ever to appear at the Metropolitan Opera.

When asked what Messiaen's main influence had been on composers, George Benjamin said, " I think the sheer [...] colour has been so influential, [...] rather than being a decorative element, showed that colour could be a structural, a fundamental element, [...] the fundamental material of the music itself.

He directed many satirical remarks at his opponents, an especially characteristic one being his designation of the typical Talmudist of his day as “ a man who through sheer study of the Law has no time to think about God ”.

This has given them a reputation for pushiness, yet it should also be said that in terms of ambition, attention to display and sheer bravado there has been little to match such shows in the country's established contemporary art institutions.

The film received a mixed reception, Variety wrote, " as a lighthearted satire on British army life during the last war, Private's Progress has moments of sheer joy based on real authenticity.

He described the book as " a virtual encyclopedia of Japanese history and culture ; somewhere among those half-million words, one can find a brief description of virtually everything one wanted to know about Japan ", and stated that " n sheer quantity, Shōgun has probably conveyed more information about Japan to more people than all the combined writings of scholars, journalists, and novelists since the Pacific War.

The second northernmost, Atlasov Island ( Oyakoba in Japanese ), is an almost perfect volcanic cone rising sheer out of the sea ; it has been praised by the Japanese in haiku, wood-block prints, and other forms, in much the same way as the better-known Mt.