The first proposed mechanism of action of the hygiene hypothesis stated that insufficient stimulation of the T < sub > h </ sub > 1 arm, stimulating the cell defence of the immune system, leads to an overactive T < sub > h </ sub > 2 arm, stimulating the antibody-mediated immunity of the immune systems, which in turn led to allergic disease.

Radiation hormesis ( also called radiation homeostasis ) is the hypothesis that low doses of ionizing radiation ( within the region and just above natural background levels ) are beneficial, stimulating the activation of repair mechanisms that protect against disease, that are not activated in absence of ionizing radiation.

Faustman's hypothesis, contrary to conventional thinking, is that blocking TNF-α actually promotes the survival of undesirable autoreactive T cells, and that certain autoimmune diseases can be treated by stimulating TNF-α to trigger apoptosis in autoimmune T cells.

It was very stimulating.

In an attempt to reverse the downhill trend by stimulating the bone marrow and controlling any hemolytic component, triamcinolone, 16 mg. daily, was begun on Sept. 26, 1958, and continued until Feb. 18, 1959.

It was especially important for preserving in its libraries manuscripts of Greek and Latin authors throughout a period when instability and disorder caused their mass-destruction in western Europe and north Africa: On the city's fall, thousands of these were brought by refugees to Italy, and played a key part in stimulating the Renaissance, and the transition to the modern world.

Fox was able to meet some of the New England Friends when they came to London, stimulating his interest in the colonies.

It cleared up many confusions, and was directly responsible for stimulating a great deal of research in the post-World War II era.

In the 1950s the Cassa per il Mezzogiorno was set up as a huge public master plan to help industrializing the South, aiming to do this in two ways: through land reforms creating 120, 000 new smallholdings, and through the " Growth Pole Strategy " whereby 60 % of all government investment would go to the South, thus boosting the Southern economy by attracting new capital, stimulating local firms, and providing employment.

Nehru wrote: " Decidedly the atmosphere was not intellectually stimulating and a sense of the utter insipidity of life grew upon me.

It has been said, however, that the influence he exerted on those who attended his lectures was not beneficial in this respect, that his opinions were delivered so dogmatically, and all who differed from him were disparaged and denounced so contemptuously, as to repress instead of stimulating inquiry.

The currency was devalued and food prices were allowed to rise in the hope of stimulating agricultural production.

At the same time, his encounter with modernism was very stimulating: Rilke became deeply involved in the sculpture of Rodin, and then with the work of Paul Cézanne.

Common Sense introduced no new ideas, and probably had little direct effect on Congress's thinking about independence ; its importance was in stimulating public debate on a topic that few had previously dared to openly discuss.

It then was suggested that the mechanical stresses during phonation were stimulating the fibroblasts to synthesize those fibers.

But this margin requirement was reduced four times before 1960, each time stimulating a mini-rally and boosting volume, and when the Federal Reserve reduced the margin requirements from 90 % to 70 %.

This had the effect of immediately stimulating the trade in West Indian timbers, of which the most important was mahogany.

Instead of kissing, Manchu mothers used to show affection for their children by performing fellatio on their male babies, placing its penis in their mouths and stimulating it, since it was not considered a sexual act, while the Manchu regarded public kissing with revulsion, which was considered sexual.

While the banking system evolved in the Low Countries, it was quickly incorporated by the well-connected English, stimulating English economic output.

Coca was first introduced to Europe in the 16th century, but did not become popular until the mid-19th century, with the publication of an influential paper by Dr. Paolo Mantegazza praising its stimulating effects on cognition.

Cain was a Keynesian, opposed to the doctrines of economic rationalism, and he increased government spending in the hope of stimulating growth and investment.

The Manchester Guardian wrote, " The wonderful thing about him was his amazing versatility, and there was an intellectual virility, an untiring earnestness about the man, which was irresistibly stimulating.

In the past, castile soap was a common additive in an enema, but it has largely fallen out of use because of its irritating action in the rectum and because of the risk of chemical colitis as well as the ready availability of other enema preparations that are perhaps more effective than soap in stimulating a bowel movement.

In the past, trifluoperazine was used in fixed combinations with the MAO inhibitor ( antidepressant ) tranylcypromine to attenuate the strong stimulating effects of this antidepressant.

Nicotine is believed to act as an antidepressant, by it stimulating the release of dopamine and norepinephrine ; additionally, nicotine is believed to exert an antidepressant effect due to the desensitisation of nicotinic receptors which occurs as a result of tolerance.

Adenylate cyclase is dually regulated by G proteins ( Gs stimulating activity and Gi inhibiting it ), and by forskolin, as well as other isoform-specific effectors:

Nitrates cause vasodilation of the venous capacitance vessels by stimulating the endothelium-derived relaxing factor ( EDRF ).

It sets out Nimzowitsch's most important ideas, while his second most influential work, Chess Praxis, elaborates upon these ideas, adds a few new ones, and has immense value as a stimulating collection of Nimzowitsch's own games accompanied by his idiosyncratic, hyperbolic commentary which is often as entertaining as instructive.

Osteoblasts can also be induced to secrete a number of cytokines that promote reabsorbtion of bone by stimulating osteoclast activity and differentiation from progenitor cells.

But most historians now make a distinction between medical lancing ( or bloodletting ) and acupuncture in the narrower sense of using metal needles to treat illnesses by stimulating specific points along circulation channels (" meridians ") in accordance with theories related to the circulation of Qi.

The Flynn effect can be explained by a generally more stimulating environment for all people.

* G < sub > αs </ sub > activates the cAMP-dependent pathway by stimulating the production of cAMP from ATP.

Hypersecretion of thyroid stimulating hormone ( TSH ), which in turn is almost always caused by a pituitary adenoma, accounts for much less than 1 percent of hyperthyroidism cases.

A low TSH level typically indicates that the pituitary gland is being inhibited or " instructed " by the brain to cut back on stimulating the thyroid gland, having sensed increased levels of T < sub > 4 </ sub > and / or T < sub > 3 </ sub > in the blood.

For the stem cells and other undifferentiated blood cells in the bone marrow, the determination is generally explained by the determinism theory of haematopoiesis, saying that colony stimulating factors and other factors of the haematopoietic microenvironment determine the cells to follow a certain path of cell differentiation.

See Michael Buckland's conclusion: " Bush's contributions in this area were twofold: ( i ) A significant engineering achievement by the team under his leadership in building a truly rapid prototype microfilm selector, and ( ii ) a speculative article, ' As We May Think ,' which, through its skillful writing and the social prestige of its author, has had an immediate and lasting effect in stimulating others.

In addition, partners simultaneously stimulating each other's sex organs by mutual masturbation, penetrative intercourse, or other rhythmic inter-genital contact may experience simultaneous orgasms.

Contemporary artists have been greatly influenced by René Magritte's stimulating examination of the fickleness of images.

The bulk of remittances are sent by Somalis based abroad to relatives in Somalia, a practice which has had a stimulating effect on the country's economy.

Most steroid hormones have receptors within the cytoplasm and act by stimulating the binding of their receptors to the promoter region of steroid-responsive genes.

President Harding convened the Conference of Unemployment in 1921, headed by Secretary of Commerce Herbert Hoover, that proactively advocated stimulating the economy with local public work projects and encouraged businesses to apply shared work programs.

The government has also established a free port area, which provides the following benefits: contribution to economic diversification by providing a window for free trade as well as stimulating the establishment of support services ; administration of a regime that imports, exports, and warehouses general merchandise ; adequate storage facilities and other infrastructure to cater for effective operation of trade ; and creation of an efficient management system for effective re-exportation of goods.

The TCM theory for the selection of such points and their effectiveness is that they work by stimulating the meridian system to bring about relief by rebalancing yin, yang and qi ( also spelled " chi ").