Once cytochrome c is released it binds with Apoptotic protease activating factor-1 ( Apaf-1 ) and ATP, which then bind to pro-caspase-9 to create a protein complex known as an apoptosome.

They are similar to transpositional puns, but often much less complex and easier to create.

The population by this period were exclusively of our own species of the genus homo, homo sapiens sapiens, and the evidence would suggest that their societies were increasingly complex and they were manipulating their environment and their prey in new ways, possibly selective burning of the then omnipresent woodland to create clearings where the herds would gather to make them easier to hunt.

Most recently, James Madison University has used funds to create a new baseball and softball field complex by Memorial Hall.

Some more advanced knitting techniques create a surprising variety of complex textures.

As a student at secondary school in Warsaw, Zamenhof made attempts to create some kind of international language with a grammar that was very rich, but also very complex.

Because observations are subject to uncertainty and weather conditions, and astronomical methods are highly complex, there have been attempts to create fixed arithmetical rules.

The main cause of the Duchenne and Becker types of muscular dystrophy is the muscle tissue's cytoskeletal impairment to properly create the functional protein dystrophin and dystrophin-associated protein complex.

The advent of photosynthesis in very basic forms of plant life worldwide allowed the sun's energy to be harvested to create conditions allowing for more complex life.

The Vikings in particular were fond of twisting bars of steel around each other, welding the bars together by hammering and then repeating the process with the resulting bars, to create complex patterns in the final steel bar.

With magnetic tape, these effects could be produced in advance and the BBC engineers were able to create highly complex, tightly edited effects ' stings ' that would have been very difficult ( if not impossible ) to perform using foley or disc.

As the more complex sound signal is broken into the smaller sub-sounds, different levels are created, where at the top level we have complex sounds, which are made of simpler sounds on lower level, and going to lower levels even more, we create more basic and shorter and simpler sounds.

Patterns can be saved like any other first-class data item, and can be concatenated, used within other patterns, and used to create very complex and sophisticated pattern expressions.

Morris's patterns for woven textiles, some of which were also machine made under ordinary commercial conditions, included intricate double-woven furnishing fabrics in which two sets of warps and wefts are interlinked to create complex gradations of colour and texture.

By and large, the theories of existentialism assert that conscious reality is very complex and without an " objective " or universally known value: the individual must create value by affirming it and living it, not by simply talking about it or philosophising it in the mind.

For example, individual atoms can be combined to form molecules such as polypeptide chains, which in turn fold and refold to form proteins, which in turn create even more complex structures.

SGA has not had much other official use after that, but Tom Hall invented a syllabary to create a more complex " alien " language used in Ion Storm's Anachronox.

These minor problems include the inability to create syntactically complex sentences including more than two subjects, multiple causal conjunctions, or reported speech.

Please help separate and categorize these further and create detailed pages for them, especially the more complex ones, or link to one where one exists.

CATIA provides a suite of surfacing, reverse engineering, and visualization solutions to create, modify, and validate complex innovative shapes.

A situation calls a rhetor to create discourse, it invites a response to fit the situation, the response meets the necessary requirements of the situation, the exigence which creates the discourse is located in reality, rhetorical situations exhibit simple or complex structures, rhetorical situations after coming into creation either decline or persist.

It will create a mixed-use complex, multi-functional buildings, visual landmarks and a public space in the Thames Valley.

Bottom-up approaches seek to have smaller ( usually molecular ) components built up into more complex assemblies, while top-down approaches seek to create nanoscale devices by using larger, externally controlled ones to direct their assembly.

The dentist who had hired him to look after his office during his lunch hour did the same when he found Danny using his drill to create designs in the office woodwork.

Cheney had no formal training as a motorcycle designer yet was able to create original and high performance motorcycle chassis designs working in a simple workshop that was essentially a domestic garage.

In 1848 James B. Francis, while working as head engineer of Lowell's Locks and Canals company, improved on these designs to create a turbine with 90 % efficiency.

Shortages of funding meant it was not possible to create several designs of cruisers specialised for long range work, or more heavily armoured for fleet work.

In a letter to the Quartermaster General ( QMG ) dated December 24, 1941, the Adjutant General formally requested action be initiated to create a Meritorious Service Medal and provide designs in the event the decoration was established.

He went on to create his own designs based on his knowledge of transistor – transistor logic and Bushnell's game.

Roxy Music was one of the first rock music groups to create and maintain a carefully crafted look and style that included their stage presentation, music videos, album and single cover designs, and promotional materials such as posters, handbills, cards and badges.

His images, including set designs for the Ballets Russes, would create a decorative form of Surrealism, and he would be an influence on the two artists who would be even more closely associated with Surrealism in the public mind: Dalí and Magritte.

The medium is not limited to just simple designs ; it can be used to create complex paintings, just as in other media such as oil and acrylic.

Many professional embroidery operations still refer to those individuals who create the designs and machine patterns as " punchers ", even though punched cards and paper tape were eventually phased out, after many years of use, in the 1990s.

His writings and designs stress the need to create meaningful, vital, and inclusive spaces that enhance community, with special attention to the essence of a particular locale, geography, and culture.

Over the years, unicycle enthusiasts have inspired manufacturers to create new designs, such as seatless (" ultimate wheel ") and tall (" giraffe ") unicycles.

A year later, the Mackintoshes moved to London where he continued to paint and create textile designs.

For his early, short films O ' Brien created his own characters out of clay, although for much of his feature career he would employ Richard and Marcel Delgado to create much more detailed stop-motion models ( based on O ' Brien's designs ) with rubber skin built up over complex, articulated metal armatures.

Knapped and unknapped flints are arranged in patterns, textures and designs and create the stone work.

Roof-prisms designs create an instrument that is narrower and more compact than Porro prisms.

Those different designs create certain optical parameters ( some of which may be listed on the prism cover plate of the binocular ).

For example, a series of flower designs might be cut out of one fabric with a vine design, rearranged and sewn down on a new fabric, to create the image of a rose bush.

In the context of sewing, an appliqué refers to a needlework technique in which pieces of fabric, embroidery, or other materials are sewn onto another piece of fabric to create designs, patterns or pictures.

Some of the skeletons are intact and draped with Franciscan habits, but for the most part, individual bones are used to create elaborate ornamental designs — as was popular at that period.

Aerotech, Pro-38, Rouse-Tech, Loki and others have standardized around a set of common reload sizes such that customers have great flexibility in their hardware and reload selections, while there continues to be an avid group of custom engine builders who create unique designs and occasionally offer them for sale.

However, by raising different warp threads during weaving, it is possible to make fabrics of different textures or to vary the texture, or even the color, of the cloth in order to create patterns or designs.

Most notable were the attempts to create several of Leonardo da Vinci's designs from his sketchbooks, such as the 16th century tank.

Software also lets artists create their own designs and output them using their computer's color printer.