Without histones, the unwound DNA in chromosomes would be very long ( a length to width ratio of more than 10 million to one in human DNA ).

: Without hoping to know whether each separate hypothesis is true or false, we may search for rules to govern our behaviour with regard to them, in following which we insure that, in the long run of experience, we shall not be too often wrong.

Without the prospect of long distance services, the market position of many independents became untenable.

Without a DNA sample, it is not possible to reconstruct the complete genetic makeup ( genome ) of any individual who died very long ago.

Without a retrorocket burn long enough to reduce its velocity sufficiently for a survivable landing, Luna 8 plummeted to the lunar surface and crashed at 21: 51: 30 UT on 6 December just west of the Kepler Crater.

Without a public facility, all meetings were held in their homes and long hours spent on village business.

Without going after business, for his letters do not indicate that he was ever aggressive or pushy, Copley was started as a professional portrait-painter long before he was of age.

Black Market Music did not receive the same level of long term recognition and media hype as Without You I'm Nothing did, but its peak sales outperformed those of its predecessor in both the UK and France.

" Without such efforts, he said, Taiwanese will be unable to survive long into the future.

Without a true tail to provide thrust for forward motion and equipped with only small pectoral fins, Mola mola relies on its long, thin dorsal and anal fins for propulsion, driving itself forward by moving these fins from side to side.

Without caps there is a risk that teams will overspend in order to win now at the expense of long term stability.

Without pausing to consider these objections, Fabre and D ' Aboville took their " discovery " to General Gonse, deputy-chief of the staff, and to Colonel Sandherr, an anti-Semite of long standing.

Without aircraft able to cover the long distance, activities in the South Atlantic would be carried out by the Royal Navy and the British Army.

Without an in-flight refuelling system it was unable to loiter long.

Without spooling, most programs would be relegated to patterns of fast processing and long waits, an inefficient paradigm.

" Life Without You " is essentially a long jam, with two extended guitar parts separated by break in which ( with bassist Tommy Shannon and drummer Chris Layton still playing ) Vaughan completes a short monologue on his troubles with substances abuse and his newly-found sobriety.

Without the Pif1 helicase, the flaps would not become long enough to need cleavage by Dna2.

Without the size constraints of smaller hearing devices body worn aid designs can provide large amplification and long battery life at a lower cost.

Without aircraft, ships, or hope of reinforcement or relief, the outnumbered and outgunned defenders could only hope to delay the coming American attack for as long as possible.

Without the telephone, one could not have a conversation across long distances ; and without the sanctified image in the temple, one cannot easily talk with the Deity .” Moreover, anthropologist Christopher John Fuller notes that an image in Hinduism cannot be equated with a deity and the object of worship is the divine whose power is inside the image, and the image is not the object of worship itself, Hindus believe everything is worthy of worship as it contains divine energy emanating from the one god.

Without the dam, the long term costs for people would be much greater and lack of an income source for future generations would put increasing pressure on the environment.

Without Witnesses ( 1983 ) tracks a long night's conversation between a woman ( Irina Kupchenko ) and her ex-husband ( Mikhail Ulyanov ) when they are accidentally locked in a room.

Without highways of access, the route had to be done on horse, in long and painful caravans from the coast, or by the rivers from the region of the east.

This was the Year Without a Summer caused by volcanic dust in the atmosphere: the local press reported floods, ' long continued wet weather ', unripened wheat and widespread civil unrest.

Without someone to release them in the event of an emergency or medical crisis, self-bondage can be lethal to its practitioners.

Without emergency oxygen hypoxia may lead to loss of consciousness and a subsequent loss of control of the aircraft, the time of useful consciousness varying according to altitude.

Without fixed ropes to retreat down in case of emergency, or a lower camp to return to, the commitment of alpine style is greater than expedition style in terms of the choice to ascend or descend.

Without the decay of a sense of objective reference ( except as the imitation of mystery ), the stress on subjective invention would never have been stimulated into being.

Without saying or seeming to say that in portraying the Sartoris and the Compson families Faulkner's chief concern is social criticism, we can say nevertheless that through those families he dramatizes his comment on the planter dynasties as they have existed since the decades before the Civil War.

Without exception Hino's brothers turned to either one or both of their father's occupations, but Hino showed a talent for neither and instead spent most of his time on the beach where he repaired nets and proved immensely popular as a storyteller.

Without comment he opened the closet and from its shelves constructed a highboard around the egg case which he had placed on the floor inside.

Without agreeing with every phrase in this statement, we must certainly assert the great difference between Christian love and any form of resistance, and then go on beyond the Mennonite position and affirm that Christian love-in-action must first justify and then determine the moral principles limiting resistance.

`` Without any officious and improper interference on the subject, the price of labor or the wages of mechanics will be regulated by the demand for the manufactured article and the value of that which is paid for it ; ;

Turning to the current musical season on Broadway, the most widely acclaimed of the new arrivals, How To Succeed In Business Without Really Trying, has been transferred to an original cast album ( R. C. A. Victor LOC 1066 ; ;

Without an instant's transition, the green light that meant full fusion power winked on the board.

Without apostles or prophets left on the earth with the legitimate Priesthood Authority, the true teachings and practices of Christianity were lost.

Without such precautions, most programs may compile only on a certain platform or with a particular compiler, due, for example, to the use of non-standard libraries, such as GUI libraries, or to the reliance on compiler-or platform-specific attributes such as the exact size of certain data types and byte endianness.

Without their best general and his veterans, the French suffered a series of defeats and it was not until Bonaparte returned to become First Consul that France once again held a position of strength on mainland Europe.

In 1961, Billy played on the Alfred Hitchcock Presents TV series on episode " Door Without a Key.

Without one official teaching on the death penalty, Thai monks are typically divided on the issue with some favoring abolition of the death penalty while others see it as bad karma stemming from bad actions in the past.

His best known films are La jetée ( 1962 ), A Grin Without a Cat ( 1977 ), Sans Soleil ( 1983 ) and AK ( 1985 ), an essay film on the Japanese filmmaker Akira Kurosawa.

Marker then began work on one of his most ambitious films, A Grin Without a Cat, released in 1977.

Poole refers to Calef as Mather's " personal enemy " and opens a line, " Without discussing the character and motives of Calef ..." and he does not follow up on this suggestiveness, to discuss any motive or reason to impune Calef's character.

Without an equally strong convergence on the new result, the weight of evidence will still favor the established result.

: Without doubt this is the most important work on general algebra that the Annalen has ever published.

* Dan Simmons on Worlds Without End

" Without these questions there is no clear fulcrum on which to balance law, politics, and the practice of arbitration — in fact, no common assumptions of all participants — so the ability to formulate the questions are prior to rights balancing.