Large-scale dealing, production, import and export are prosecuted to the fullest extent of the law, even if it does not supply end users or coffeeshops with more than the allowed amounts.

Large-scale production resulted from the development of deep-tank fermentation by chemical engineer Margaret Hutchinson Rousseau.

Large-scale production began in 1890.

Large-scale production of MDF began in the 1980s, in both North America and Europe.

Large-scale production of the weapon was from 1921-1930.

Large-scale production tragic Democratic dell ' Atene there remained only a few plays of three authors: Aeschylus, Sophocles and Euripides.

Large-scale wall-paintings were apparently much less regarded, relatively crudely executed, and rarely mentioned in contemporary sources ; they were probably seen as a cheap but inferior substitute for mosaic, which in this period must be treated as a fine art, though in recent centuries contemporary production has tended to be seen as decorative.

Large-scale production began in 1934, and in the same year the factory was put under NKVD control and Makarenko was fired.

Large-scale sheep farming, wool production and weaving were the mainstay of Helmsley ’ s economy for several centuries.

Large-scale construction for multifaceted retirement communities is a new phase of industrial development.

Large-scale investment in new facilities were promised, and Sol Campbell and Kasper Schmeichel joined the club from Premier League teams.

Large-scale pre-planning and extensive project scheduling are replaced by smaller experiments, which can be rapidly adapted as new improvements are suggested.

Large-scale demonstrations in the cities and a general strike prevented the formation of a new socialist government.

Large-scale property developments along the West Rail were originally planned to generate new passenger demand but were delayed by government policy.

Large-scale home builders such as Beazer and Centex Homes have constructed many new subdivisions.

Large-scale updates / expansions known as " Chronicles " are done every six months, which introduce new story elements as well as new features and add-ons.

Large-scale demolition took place along the line of the motorway ( which is still evident today ), tied in with the widening of the Belle Vue and Reddish Lane junctions.

Large-scale wars in the nineteenth century, such as the Crimean War, American Civil War, and Franco-Prussian War introduced increasing numbers of working-class men to canned food, and allowed canning companies to expand their businesses to meet military demands for non-perishable food, allowing companies to manufacture in bulk and sell to wider civilian markets after wars ended.

Large-scale transportation ended in 1853 ( although the practice continued on a reduced scale until 1867 ); and Millbank then became an ordinary local prison, and from 1870 a military prison.

Large-scale emigration, principally to the United States, and Canada ( predominantly to Quebec, with other areas of the country )-but also to Cuba, other areas of Europe and the Americas such as France ( with French Guiana ), Spain, Belgium, the United Kingdom and Ireland ; and Venezuela, the Dominican Republic, the Bahamas and other Caribbean neighbors-has created what Haitians refer to as the Eleventh Department or the Diaspora.

* November 21 – Large-scale Bleeding Kansas violence begins with events leading to the Wakarusa War between antislavery and proslavery forces.

* Armenia: Large-scale Armenian rebellion against Muslim rule breaks out with Byzantine support.

Large-scale industrialization began in 1954 with the arrival of a General Motors assembly plant.

Large-scale laser systems can produce Q-switched pulses with energies of many joules and peak powers in the gigawatt region.

Large-scale development of Kowloon began in the early 20th century, with the construction of the Kowloon-Canton Railway and the Kowloon Wharf, but due to Kowloon's close proximity to Kai Tak Airport, building construction was limited by flight paths.

Large-scale immigration of Chinese began seventy years later with the advent of the Fraser Canyon Gold Rush of 1858.

Large-scale sculptures of the type characteristic of cult images are also to be found in the collection, including Jupiter and Neptune, as well as various mythological reliefs, among them the Bacchic Altar, a Neo-Attic work of the late Hellenic period, and the Sarcophagus with the Story of Achilles and Polyxena.

Large-scale pieces such as De Staat ( 1972 – 76 ), for example, are influenced by the energy of the big band music of Count Basie and Stan Kenton and the repetitive procedures of Steve Reich, both combined with bright, clashing dissonances.

Large-scale development began in February 1950 with the construction of the Southdene neighbourhood, with the first houses finished in 1952, the 5, 000th in 1956 and the 10, 000th in 1961.

Large-scale habitat destruction and fragmentation has undoubtedly been important, and may well be the major factor, although there is some evidence that suggests the birds clearly favours agricultural land with patches of remnant native vegetation over intact areas of vegetation.

Large-scale excavations were conducted at various times between 1930 and 1937 by Homer Thompson, in collaboration first with K. Kourouniotes and later with Robert Scranton.

Large-scale Japanese immigration to the United States began early in the 20th century, and traditional music came with them.

) Large-scale interplanetary travel is now commercially viable with muon-catalyzed fusion-powered spacecraft.

Large-scale resemblances in plotting — the missing prince, the ruler and his heir who fall in love with the same woman — could be explained through derivation from common sources ; but these larger-scale elements are supported by specific lines and passages that occur in both plays.

Large-scale manufacturers can effectively bargain with suppliers for discounts on materials.

Large-scale commercial development began with Colony Square, the first mixed-use development in the Southeast, which was built between 1969 and 1973.

Large-scale warfare resumed with the War of the Austrian Succession ( 1740 – 1748 ).

Large-scale development commenced with the arrival of the Southern Pacific Railroad in 1875, with numerous electric streetcar lines being laid over the following three decades to connect the area to fast-growing Downtown Los Angeles.

Large-scale experiments have added iron ( usually as salts such as iron sulphate ) to the oceans to promote phytoplankton growth and draw atmospheric CO < sub > 2 </ sub > into the ocean.

He was the head of AT & T Lab's Large-scale Programming Research department, from its creation until late 2002.

Large-scale ship canals such as the Panama Canal and Suez Canal continue to operate for cargo transportation, as do European barge canals.

Large-scale composting systems are used by many urban areas around the world.

Large-scale population movements from rural to urban areas of Latin America and to other regions of the world have increased the geographic distribution of Chagas disease, and cases have been noted in many countries, particularly in Europe.

Large-scale structures are very long arcs which can cover over a quarter of the solar disk but contain plasma less dense than in the coronal loops of the active regions.

Large-scale air raids in World War II, including the preliminary bombing during Operation Market Garden to aid the US 101st Airborne Division paratroopers in securing the bridges in and around the town on 18 September 1944, destroyed large parts of the city.

Large-scale purges of officials occurred during the 1970s.

Large-scale retrieval systems, such as the Lockheed Dialog system, came into use early in the 1970s.

Large-scale and medium-scale industries are concentrated in North Jakarta.

Large-scale features may include limestone pavements, poljes, and karst valleys.

Large-scale gene transfer has also occurred between the ancestors of eukaryotic cells and prokaryotes, during the acquisition of chloroplasts and mitochondria.

Large-scale petrol-mechanical and petrol-hydraulic models are available but unusual and pricier than the electrically powered versions.

Large-scale evaluation of dependency parsers were performed in the context of the CoNLL shared tasks in 2006 and 2007.

Large-scale quantum computers could be able to solve certain problems much faster than any classical computer by using the best currently known algorithms, like integer factorization using Shor's algorithm or the simulation of quantum many-body systems.

Large-scale use of quinine as a prophylaxis started around 1850.

Large-scale use of chemicals for cotton cultivation, inefficient irrigation systems, and poor drainage systems are examples of the conditions that led to a high filtration of salinized and contaminated water back into the soil.

Large-scale land clearing for agriculture has damaged habitats for native flora and fauna.

Large-scale wildebeest migration is quite likely a consequence of decisions being made by individuals at multiple spatial scales, involving a balance of food abundance, food quality, local density of other wildebeest, social interactions, surface water, perceived predation risk, and culturally ( or possibly genetically ) learned routes and ranges.

* Large-scale decolonization in Africa first began in the 1950s.

* Large-scale Viking attacks on Europe begin, devastating countless numbers of people.

* Large-scale Abbasid raid under Caliph al-Ma ' mun into Cappadocia.