So we asked such men in major companies in the design field to offer their opinions on the `` dual-road-up '' problem -- and more importantly -- their solutions.

A well-publicized entrant which has achieved success only recently is the built liquid detergent, with which the major problem today is incorporation of builder and active into a small volume using a sufficiently high builder/active ratio.

Our major problem is what an enemy might accomplish in an initial attack on a target.

However, a major problem here is one of scale of processing ; ;

Hardly a window has been broken since Dunbar first was opened ( and vandalism in schools is a major problem in many slum areas ).

Indeed, the problem of determining the area of plane figures was a major motivation for the historical development of calculus.

In medicine, the major problem of the emergence of resistant bacteria is due to misuse and overuse of antibiotics.

The authors noted an apparent superior efficacy of olanzapine to the other drugs in terms of reduction in psychopathology and rate of hospitalizations, but olanzapine was associated with relatively severe metabolic effects such as a major weight gain problem ( averaging over 18 months ) and increases in glucose, cholesterol, and triglycerides.

The questions can concern anything from a major policy issue to a specific constituent's problem.

This became a major problem as bidding wars between the ballclubs to land the best amateur players escalated signing bonuses.

Another major problem in cosmology is what caused the universe to contain more particles than antiparticles.

The P versus NP problem is a major unsolved problem in computer science.

A major problem in determining whether the Cimbri were speaking a Celtic or a Germanic language is that at this time the Greeks and Romans tended to refer to all groups to the north of their sphere of influence as Gauls, Celts, or Germani rather indiscriminately.

Further, 43 percent of respondents said they use less than half the functionality of their existing system ; 72 percent indicated they would trade functionality for ease of use ; 51 percent cited data synchronization as a major issue ; and 67 percent said that finding time to evaluate systems was a major problem.

Chronic Chagas disease remains a major health problem in many Latin American countries, despite the effectiveness of hygienic and preventive measures, such as eliminating the transmitting insects.

The disease was named after the Brazilian physician and infectologist Carlos Chagas, who first described it in 1909, but the disease was not seen as a major public health problem in humans until the 1960s ( the outbreak of Chagas disease in Brazil in the 1920s went widely ignored ).

In an account that had become standard by the mid-century, Hilbert's problem set was also a kind of manifesto, that opened the way for the development of the formalist school, one of three major schools of mathematics of the 20th century.

Thus far, pyrethroid resistance in Anopheles has not been a major problem.

This prediction came true at least in part: Doom became a major problem at workplaces, both occupying the time of employees and clogging computer networks with traffic caused by deathmatches.

The Stammbaumtheorie proved to be very productive for comparative linguistics, but didn't solve the major problem of studying the origin of language: the lack of fossil records.

In the 21st-century Egypt has encountered a major problem with immigration, as millions of Africans attempt to enter Egypt fleeing poverty and war.

A major problem has been that bacteria do not consume all parts of the malignant tissue.

A major problem at that time was the lack of fossil intermediaries.

The major reason for this is that it has no quick-kill effect.

National defense considerations have been the major reason behind most Federal training expenditures in recent decades.

A major reason for the all-day congestion was that the Central Artery carried not only north – south traffic, but much east – west traffic as well.

Deane and J. R. Thomson write this valid conclusion, “ The Book of Obadiah is occupied with one subject – the punishment of Edom for its cruel and unbrotherly love conduct towards Judah ...” One can link this idea of punishment to one of the major prophets “ Ezekiel ” who “... interprets the exile to Babylon and the destruction of Jerusalem as deserved punishments for the sins of those who themselves committed them .” Verses 3-7 in Obadiah explain to the reader the reason for the punishment theme, “ Confidence in one ’ s power, intelligence, allies, or the topographical features of one ’ s territory is often mentioned as an attribute of those who foolishly confront the Lord and are consequently punished .” Although destruction is vital to understanding Obadiah, it is of note to understand the destruction being a consequence of action.

Under his command, a modern update of the doctrinal system called Bewegungskrieg (" maneuver warfare ") and its associated leadership system called Auftragstaktik (" mission tactics "; i. e., units are assigned missions ; local commanders decide how to achieve those missions ) was developed, which was a critical advantage and a major reason for the success of blitzkrieg.

It has been argued by John Mosier that, while the French soldiers in 1940 were better trained than German soldiers, as were the Americans later, and the German army was the least mechanised of the major armies, its leadership cadres were both larger and superior and their high standards of leadership were the primary reason for the successes of the German army in World War Two as it had been in World War One.

A major reason for the motorway construction " mania " of the 2000s is a previous political halt of the major Croatian highway project, today's A1, in the 1970s and 1980s under former Yugoslavia.

The prosperity seen from the boom in sugar production is a major reason that Cuban ethnicity became further enriched by new influx of Spanish migrants.

The US dollar is an example of a fully convertible currency and for this reason, US dollars are one of the major currencies traded in the FOREX market.

The State Planning Commission ( Gosplan ) supported giving subsidies to heavy industries, while the People's Commissariat for Finance opposed this, citing major inflation as their reason.

By contrast, Rabbinic Judaism subsequently took the opposite view, espoused by Hillel, the leader of the other major Pharisee school of thought at the time ; in Hillel's view, men were allowed to divorce their wives for any reason.

The reason why Euler and some other authors relate the Cauchy – Riemann equations with analyticity is that a major theorem in complex analysis says that holomorphic functions are analytic and viceversa.

The major opponents of the Humean view are cognitivists about what it is to act for a reason, such as John McDowell, and Kantians, such as Christine Korsgaard.

DDE related eggshell thinning is considered a major reason for the decline of the bald eagle, brown pelican, peregrine falcon, and osprey.

This is a major reason for promoting freedom.

Many Esperantists believe this declaration stabilising the language is a major reason why the Esperanto speaker community grew beyond the levels attained by other constructed languages and has developed a flourishing culture.

The French cinema market, and more generally the French-speaking market, is smaller than the English-speaking market ; one reason being that some major markets, including prominently the United States, are reluctant to generally accept foreign films, especially foreign-language and subtitled productions.

Crick described what he saw as the failure of Maurice Wilkins and Rosalind Franklin to cooperate and work towards finding a molecular model of DNA as a major reason why he and Watson eventually made a second attempt to do so.

A second major reason was that the opposition's peace feelers to the Western Allies did not meet with success.

The large number of coaching inns is, in turn, one reason why the City has so many pubs today ( another being that it was, and remains, a major centre for Christian pilgrimage ).

This period of his life, coupled with the reality of an impoverished childhood, plays a major role in the meaning behind the poem ; it is also the prime reason for this poem's existence.

For this reason, it is clear that when social and economic inequalities centered on inheritance are perpetuated by major social institutions such as family, education, religion, etc., these differing life opportunities are transmitted from each generation.

Another major theme is the tension between free will and biological determinism, or reason and sexual desire.

System Exclusive ( SysEx ) messages are a major reason for the flexibility and longevity of the MIDI standard.