The oligonucleotide probe hybridizes with the repeat in the microsatellite, and the probe / microsatellite complex is then pulled out of solution.

The probe thereby hybridizes to single-stranded nucleic acid ( DNA or RNA ) whose base sequence allows probe-target base pairing due to complementarity between the probe and target.

A target-specific probe, composed of 20 oligonucleotide pairs, hybridizes to the target RNA ( s ).

A target-specific probe, composed of 20 oligonucleotide pairs, hybridizes to the target RNA ( s ).

The probe hybridizes to the target sequence at elevated temperature, and then the excess probe is washed away ( after prior hydrolysis using RNase in the case of unhybridized, excess RNA probe ).

Fourth, in the meantime, it is necessary to remember that we have only begun to probe the environment immediately surrounding the earth.

Atom probe devices have only relatively recently been produced commercially, and many designs have been constructed since the method's inception.

It is still not clear how far Orkney ’ s advance was planned only as a feint ; according to historian David Chandler it is probably more accurate to surmise that Marlborough launched Orkney in a serious probe with a view to sounding out the possibilities of the sector.

Later it was speculated that the probe passed through the debris of Comet D / Swift, and even made a close flyby of that comet's possibly shattered nucleus at only 20 million kilometers.

Since the RNA is first separated by size, if only one probe type is used variance in the level of each band on the membrane can provide insight into the size of the product, suggesting alternative splice products of the same gene or repetitive sequence motifs.

In allele " A ", the genome is cleaved by a restriction enzyme at three nearby sites ( triangles ), but only the rightmost fragment will be detected by the probe.

In allele " d " there are only two repeats in the VNTR, so the probe detects a shorter fragment between the same two restriction sites.

Of the moons discovered by the Voyager 2 imaging team, only Puck was discovered early enough that the probe could be programmed to image it in some detail.

Machines, such as the Nomad probe, have been melded with even if only through complete contact.

DOS versions prior to 5. 0 will probe for only two physical harddisks, whereas DOS 5. 0 and higher support eight physical harddisks.

Because the biased tip configuration is floating, the positive probe can draw at most an electron current only equal in magnitude and opposite in polarity to the ion saturation current drawn by the negative probe, given by:

Venera 13 and 14 were the only landers on which all cameras worked properly ; although unfortunately, the titanium lens cap on Venera 14 landed precisely on the area which was targeted by the soil compression probe.

Observations could only be conducted when the probe was closer than 4700 km over the planet.

All the entry probes survived the density of the Venusian atmosphere at least until impact, but only one probe survived for a significant period after impact.

Thus, the Surveyor 1 landing in June 1966, only four months after the Soviet Luna 9 probe landed in February, was an indication the programs were at similar stages.

Although space probes have returned to Earth in the decades since Apollo 12, this remains the only occasion in which humans have visited a probe that had been sent to another world.

Initial radio contact showed that the signal from the space probe was only about one-half as strong as expected, and the internal temperature was rising.

She tried to probe into her inner-self and declared that she would sing only those songs which have a meaning for her.

Washington continued to probe the New York area, until August 14, when he received a letter from de Grasse that he was headed to Virginia with 29 warships and 3, 200 men, but would only remain there until October 14.

In this manner, a continuous stream of data could be collected about distant solar systems even though any given Starwisp probe only spends a few days travelling through it.

The Huygens probe entered the upper layer of Titan's atmosphere 2. 7 hours after the end of the transit of the Earth, or only one or two minutes after the end of the transit of the Moon.

Aided by the slowly spinning probe they would build up a full mosaic of the landing site, which, surprisingly, became clearly visible only below 25 kilometers altitude.

Scanning probe microscopes also analyze a single point in the sample and then scan the probe over a rectangular sample region to build up an image.

The third season follows a single story arc, beginning in the second season finale " The Expanse ", in which a mysterious probe cuts a wide, deep trench from central Florida to Venezuela, killing seven million people.

The denaturation in an alkaline environment may improve binding of the negatively charged DNA to a positively charged membrane, separating it into single DNA strands for later hybridization to the probe ( see below ), and destroys any residual RNA that may still be present in the DNA.

# The membrane is then exposed to a hybridization probe — a single DNA fragment with a specific sequence whose presence in the target DNA is to be determined.

The most straightforward way to measure the I-V characteristic of a plasma is with a single probe, consisting of one electrode biased with a voltage ramp relative to the vessel.

The theory is similar to that of a single probe, except that the current is limited to the ion saturation current for both positive and negative voltages.

On the other hand, it shares the limitations of a single probe concerning complicated electronics and poor time resolution.

After each single measurement, the probe is rinsed with distilled water or deionized water to remove any traces of the solution being measured, blotted with a scientific wipe to absorb any remaining water which could dilute the sample and thus alter the reading, and then quickly immersed in another solution.

Dual-color FISH with a c-MYC probe mapping to 8q24 revealed colocalization with HPV18 at all integration sites, indicating that dispersion and amplification of the c-MYC gene sequences occurred after and was most likely triggered by the viral insertion at a single integration site.

The design's strategy was to use the probe to deliver a " seed " factory with a mass of about 443 tons to a distant site, have the seed factory replicate many copies of itself there to increase its total manufacturing capacity, over a 500 year period, and then use the resulting automated industrial complex to construct more probes with a single seed factory on board each.

Sometimes both pressure sources are combined in a single probe, a pitot-static tube.

The non-replicating design was modified to include all subsystems necessary for self-replication, using the probe to deliver a " seed " factory with a mass of about 443 metric tons to a distant site, having the seed factory replicate many copies of itself there to increase its total manufacturing capacity, and then using the resulting automated industrial complex to construct more probes with a single seed factory on board each over a 1, 000 year period.

A JTAG interface is a special four / five-pin interface added to a chip, designed so that multiple chips on a board can have their JTAG lines daisy-chained together if specific conditions are met, and a test probe need only connect to a single " JTAG port " to have access to all chips on a circuit board.

As the series presents it, known human contact with the Chigs begins when an unmanned probe, launched by the military-industrial corporation Aerotech, lands on a celestial body designated " celestial body 2064K " ( later given military designation ' Anvil '), the single moon orbiting the Chig homeworld.

Their most famous CBS Reports installment — the probe of migrant farm workers Harvest of Shame — aired in November 1960 and still is considered one of television's finest single programs.

The labeled probe is first denatured ( by heating or under alkaline conditions such as exposure to sodium hydroxide ) into single stranded DNA ( ssDNA ) and then hybridized to the target ssDNA ( Southern blotting ) or RNA ( Northern blotting ) immobilized on a membrane or in situ.

In April 2009, the Los Angeles Times reported that the NCAA had merged its investigations of Bush and former USC basketball player O. J. Mayo into a single probe of the Trojans athletic programs.

The design's strategy was to use the probe to deliver a " seed " factory with a mass of about 443 tons to a distant site, have the seed factory replicate many copies of itself there to increase its total manufacturing capacity, and then use the resulting automated industrial complex to construct more probes with a single seed factory on board each.

In April 2009, the NCAA combined its investigations of Mayo and former running back Reggie Bush into a single probe of the Trojans ' athletic program.

They have exploited self-assembled monolayers as well-defined environments to isolate single molecules for measurements of electron transport, as a means to improve nanofabrication techniques, and as a way to isolate probe molecules on biospecific capture surfaces.