After this initial chemotherapeutic compound proved effective, others pursued similar lines of inquiry, but it was not until in 1928 that Alexander Fleming observed antibiosis against bacteria by a fungus of the genus Penicillium.

The so-called Weil conjectures were hugely influential from around 1950 ; they were later proved by Bernard Dwork, Alexander Grothendieck, Michael Artin, and Pierre Deligne, who completed the most difficult step in 1973.

Their attempts to treat humans failed because of insufficient volumes of penicillin ( the first patient treated was Reserve Constable Albert Alexander ), but they proved it harmless and effective on mice.

Moreover the Hellanodikai, who manage the games at Olympia, decided that they were so: for when Alexander wished to contend in the games and had descended for this purpose into the arena, the Hellenes who were to run against him tried to exclude him, saying that the contest was not for Barbarians to contend in but for Hellenes: since however Alexander proved that he was of Argos, he was judged to be a Hellene, and when he entered the contest of the foot-race his lot came out with that of the first.

The attack against Egypt of the Ptolemies proved a fiasco, and the generals sent against Molon and Alexander met with disaster.

The case of the initially " unidentified man ", commonly known as " Body 115 " after its mortuary tag number, was finally solved on 22 January 2004, when forensic evidence proved that he was 73-year-old Alexander Fallon of Falkirk, Scotland.

In the earlier sculpture show, this trick proved impossible for one piece, an Alexander Calder mobile whose wire inevitably hung at a true plumb vertical, " suggesting hallucination " in the disorienting context of the tilted floor.

Despite fervent support for the Greek cause in Russian nationalist circles, Alexander proved unwilling to defy Metternich and Castlereagh and offer the Greeks more than ( limited ) diplomatic support.

After Hunt ’ s death, his son Alexander and Brinley Sleight took over, publishing the newspaper daily, though this business model proved unsuccessful and the paper reverted back to a weekly publication.

Both efforts proved fruitless, and though Alexander agreed to his grandmother's wishes, he remained respectful of his father's position as immediate successor to the Russian throne.

The first of the Weil conjectures was proved by Bernard Dwork, and a completely different proof of the first two conjectures via l-adic cohomology was given by Alexander Grothendieck.

It proved to be very influential throughout Protestantism and Anabaptism, inspiring Anglican priest John Wesley to begin the Methodist movement and Alexander Mack to begin the Brethren movement.

When Saladin learned the truth from a letter Alexander found that proved Alhazred's treachery, he immediately sided with Alexander as did the rest of the castle guards.

The issue of violence proved an insurmountable barrier to unity between the SLP and the anarchist movement, however, and as Paul Grottkau, Alexander Jonas, and their co-thinkers began to again forcefully espouse the Marxist point of view in 1884, the SLP began to rebound.

Alexander seems to have died about 242 BC, leaving his country under the regency of his wife Olympias who proved anxious to have good relations with Epirus ' powerful neighbour, as was sanctioned by the marriage between the regent's daughter Phthia and Antigonus ' son and heir Demetrius.

While the rest of Longstreet's corps was located around Suffolk, Virginia, Alexander accompanied Stonewall Jackson on his flanking march at the Battle of Chancellorsville in May 1863, and his artillery placements in Hazel Grove at Chancellorsville proved decisive.

But this second period of Persian rule proved to be nearly as short as the first, and the islands became part of the rapidly growing Macedonian Empire as Alexander the Great swept through and defeated the Persians in 332 BC, to the great relief of the islands ' inhabitants.

The army proved true to the governor-general's earlier proclamation rather than to his later fears ; the hostages were rescued, the scene of Sir Alexander Burnes's murder in the heart of Kabul was burned down.

After Odoardo's death, Pope Alexander VII allowed Queen Christina of Sweden to lodge in the palace for several months, but she " proved a tenant from hell ".

The London County Council's resident engineer, Sir Alexander Binnie, submitted a design for a steel bridge, which proved unpopular.

Eventually Elagabalus and his mother Julia Soaemias proved incompetent rulers and favour fell on Alexander, Julia's son.

After the Games, which proved a success, Vikelas withdrew from the IOC, replaced as a member by the Count Alexander Mercati and as president by Coubertin.

Interestingly enough, the order transmitted to Morgan through Alexander Hamilton also informed him that `` A party of Indians will join the party to be sent from your command at Whitemarsh, and act with them ''.

If tyrosine and a system generating hydrogen peroxide are added to a cell-free homogenate of the thyroid, large quantities of free mono-iodotyrosine can be formed ( Alexander, 1959 ).

When the mast was raised, Alexander gave the order for Small and Cromwell to be placed under arrest, and now three figures in irons sprawled upon the open deck and terror stalked the Somers.

`` That would be worse than useless '', Alexander broke in.

We are not going to be rushed and murdered '', Alexander said.

And when he was alone again in the cabin, Alexander lowered his head into his arms and wept, for he knew full well what must be done, what in the end would be done.

In one famous example, he counsels Alexander to be ' a leader to the Greeks and a despot to the barbarians, to look after the former as after friends and relatives, and to deal with the latter as with beasts or plants '.

Although his respect for Aristotle was diminished as his travels made it clear that much of Aristotle's geography was clearly wrong, when the old philosopher released his works to the public, Alexander complained " Thou hast not done well to publish thy acroamatic doctrines ; for in what shall I surpass other men if those doctrines wherein I have been trained are to be all men's common property?

Anti-Altaicists Gerard Clauson ( 1956 ), Gerhard Doerfer ( 1963 ), and Alexander Shcherbak argued that the words and features shared by Turkic, Mongolic, and Tungusic were for the most part borrowings and that the rest could be attributed to chance resemblances.

Expanding upon Foucault's position, Alexander Nehamas writes that Foucault suggests " an author [...] is whoever can be understood to have produced a particular text as we interpret it ", not necessarily who penned the text.

Alexander Balas (), ruler of the Greek Seleucid kingdom in 150 – 146 BC, was a native of Smyrna of humble origin, but gave himself out to be the son of Antiochus IV Epiphanes and Laodice IV and heir to the Seleucid throne.

In more ordinary cases Tsar Alexander III could be at once kind, simple, and even almost homely.

Though he was destined to be a strongly counter-reforming emperor, Alexander had little prospect of succeeding to the throne during the first two decades of his life, as he had an elder brother, Nicolas, who seemed of robust constitution.

Alexander had at least one illegitimate child, Máel Coluim mac Alaxandair, who was later to be involved in a revolt against David I in the 1130s.

Not to be confused with Alexander I of Yugoslavia.

In spite of this, it had been agreed with the Serbian Government that Prince Mirko of Montenegro, who was married to Natalija Konstantinovic, the granddaughter of Princess Anka Obrenovic, an aunt of King Milan, would be proclaimed Crown Prince of Serbia in the event that the marriage of King Alexander and Queen Draga was childless .< ref name =" njeg ">

*(( Hollinshed )) in his oft fanciful history of England stated that at Alexander III's wedding, a horrible monster, mostly skeleton but with raw flesh, appeared at the end of the procession and caused the wedding to be hurriedly concluded.

The Mantissa was probably not written by Alexander in its current form, but much of the actual material may be his.

It is unlikely that Alexander wrote all of the Quaestiones, some may be Alexander's own explanations, while others may be exercises by his students.

When Alexander was trying to show that he is divine so that the Greeks and Macedonians would perform proskynesis to him, Anaxarchus said that Alexander could " more justly be considered a god than Dionysus or Heracles " ( Arrian, 104 )

The Alexander technique has been shown to be helpful for people suffering from tension headaches, back pain, frozen shoulders, housemaid's knee, flat feet, tennis elbow, minor digestive problems, asthma, difficulties sleeping, clumsiness, irritability and lethargy.

Alexander believed his work could be applied to improve individual health and well being.