Alfonso had been in love with a woman of noble family named Lucrezia d ' Alagno, who served as a de facto queen at the Neapolitan court as well as an inspiring muse.

A year after her marriage to Isabella's brother, Alfonso in 1502, the notorious Lucrezia Borgia became the mistress of Francesco.

Lucrezia was married to Giovanni Sforza ( Lord of Pesaro ), Alfonso of Aragon ( Duke of Bisceglie ), and Alfonso I d ' Este ( Duke of Ferrara ).

Tomb of Alfonso I d ' Este and Lucrezia Borgia, Ferrara

Following her divorce from Sforza, Lucrezia was married to the Neapolitan Alfonso of Aragon, the half-brother of Sancha of Aragon who was the wife of Lucrezia's brother Gioffre Borgia.

Lucrezia and Alfonso had only one child, Rodrigo, who predeceased his mother in August 1512 at the age of 12.

Francesco's wife was the cultured intellectual Isabella d ' Este, the sister of Alfonso, to whom Lucrezia had made overtures of friendship to no avail.

Alfonso married the notorious Lucrezia Borgia, and continued the war with Venice with success.

His son Alfonso II married Lucrezia, daughter of grand-duke Cosimo I of Tuscany, then Barbara, sister of the emperor Maximilian II and finally Margherita Gonzaga, daughter of the duke of Mantua.

The Corpus Domini Monastery contains tombs of the House of Este, including Alfonso I, Alfonso II, Ercole I, Ercole II, as well as Lucrezia Borgia, Eleanor of Aragon, and many more.

Ercole I's successor was his son Alfonso I ( 1476 – 1534 ), third husband of Lucrezia Borgia, daughter of Pope Alexander VI, sister to Cesare Borgia and the patron of Ariosto.

His son Alfonso II first married Lucrezia, daughter of grand-duke Cosimo I of Tuscany, then after becoming a widower, Barbara, the sister of Maximilian II, Holy Roman Emperor ( 1527 – 1576 ) and finally a third wife, Margherita Gonzaga, daughter of the duke of Mantua.

In 1502 and 1503 he was again in Ferrara, and had a love affair with the notorious Lucrezia Borgia, who was the wife of Alfonso d ' Este.

Maria was the wife of Francesco d ' Este, Marchese di Massalombarda, a captain under Charles V ; Francesco was a son of the notorious Lucrezia Borgia, and her husband Alfonso I d ' Este ).

Lucrezia ’ s second marriage, to young and wealthy Prince Alfonso of Aragon, allowed the Borgias to form an alliance with another powerful family.

The third and final husband of Lucrezia was Alfonso d ' Este.

Gioffre Borgia ( 1482-1516 ), son of Pope Alexander VI and younger brother of Cesare Borgia and Lucrezia Borgia, married Sancia ( Sancha ) of Aragon, daughter of Alfonso II of Naples, obtaining as dowry both the Principality of Squillace ( 1494 ) and the Duchy of Alvito ( 1497 ).

When Lucrezia ’ s second husband, Alfonso, the Duke of Bisceglie, was no longer important to the Borgias, Cesare strangled him ( or had him strangled ) when he was still recovering from another attempt of assassination on his life.

The Villa d ' Este was commissioned by Cardinal Ippolito II d ' Este, son of Alfonso I d ' Este and Lucrezia Borgia and grandson of Pope Alexander VI.

While in Ferrara Marenzio wrote and dedicated two entire books of new madrigals to Alfonso II and Lucrezia d ' Este.

She was married in April 1528 to Ercole II, Duke of Ferrara, eldest son of Alfonso I d ' Este and Lucrezia Borgia.

Her first child, Anna, born in 1531, was followed by Alfonso, in 1533 ; Lucrezia, 1535 ; after these, Eleonora and Luigi ; whose education she carefully directed.

Alfonso Cuarón was born in México City and is the son of Alfredo Cuarón, a nuclear physicist who worked for the United Nations ' International Atomic Energy Agency for many years.

Afonso I was the son of Henry of Burgundy and Theresa of León, the natural daughter of King Alfonso VI of León.

Alfonso II ( 759 – 842 ), called the Chaste, was the king of Asturias from 791 to his death, the son of Fruela I and the Basque Munia.

Alfonso was the son of Queen Isabella II of Spain, and allegedly, of her husband and King Consort, Francis, Duke of Cádiz.

Alfonso was the eldest son of Prince Francisco de Asis de Borbón-Dos Sicilias and Queen Isabel II, whose reign was marked by a constant political crisis which had several causes.

The Prince of Asturias, Alfonso, is the person chosen to develop the new roadmap proposed by Canovas, which led to the June 1870 abdication of Queen Isabel II in favour of her son Prince Alfonso.

Alfonso was born in Madrid, posthumously born son of Alfonso XII of Spain, and became King of Spain upon his birth.

On 15 January 1941, Alfonso XIII abdicated his rights to the Spanish throne in favour of his third ( of four ), but second-surviving, son Juan, father of the current King, Juan Carlos.

* Infante Juan Carlos Teresa Silvestre Alfonso of Spain ( 1913 – 1993 ), named heir to the throne and Count of Barcelona, whose son is the current King, Juan Carlos I of Spain.

He was finally compelled to give way in Castile and León to his stepson, Alfonso VII of Castile, son of Urraca and her first husband.

Elena Lourie ( 1975 ) suggested instead that it was Alfonso's attempt to neutralize the papacy's interest in a disputed succession — Aragon had been a fief of the Papacy since 1068 — and to fend off Urraca's son from her first marriage, Alfonso VII of Castile, for the Papacy would be bound to press the terms of such a pious testament.

The choice of the Navarrese lords fell on García Ramírez, Lord of Monzón, descendant of an illegitimate son of García Sánchez III and protégé of Alfonso VII to be their king.

Alfonso, by formally submitting his reign to the Papacy, obtained the consent of Pope Eugene IV that the Kingdom of Naples would go to his immature son Ferdinand.

* Alfonso II, Count of Provence, second son of Alfonso II of Aragon.

In 1137, Aragon and the County of Barcelona merged in dynastic union by the marriage of Ramon Berenguer IV and Petronilla of Aragon, their titles finally borne by only one person when their son Alfonso II of Aragon ascended to the throne in 1162.

He had accompanied as canon Diego de Acebo, Bishop of Osma on a diplomatic mission to Denmark, to arrange the marriage between the son of King Alfonso VIII of Castile and a niece of King Valdemar II of Denmark.

Ferdinand's son, Alfonso VI of Castile took the title in 1077.

* 1469 3 June – After the death of Alfonso de Castilla and the 1st Duke of Medina Sidonia, his son and heir Enrique de Guzman, 2nd Duke of Medina Sidonia changed side and in reward, saw the status of Gibraltar, as part of the domains of the Duke, confirmed by the Queen Isabella I of Castile.

* 1492 Summer – After the death of the former Duke, his son and heir, Juan Alfonso Perez de Guzman, 3rd Duke of Medina Sidonia saw his lordship over Gibraltar reluctantly renewed by the Catholic Monarchs.

Although the former queen, Isabella II was still alive, she recognized that she was too divisive as a leader, and abdicated in 1870 in favor of her son, Alfonso.

Tradition has it that Alfonso of Aragon was an illegitimate son of the King of Naples and that her brother Cesare may have had him murdered after his political value waned.

He was made Duke of Gravina by King Alfonso, title definitely assigned to his son Giacomo ( died 1472 ), to which had been added the counties of Conversano, Campagna and Copertino.