Amphetamine, cocaine, and to a lesser extent alcohol, can result in psychosis that presents very similarly to schizophrenia.

Amphetamine, cocaine and similar drugs increase levels of dopamine in the brain and can cause symptoms which resemble those present in psychosis, particularly after large doses or prolonged use.

Mechanisms of Cocaine and Amphetamine DAT blockingDAT is also the target of several " DAT-releasers " & “ DAT-blockers ” including amphetamines and cocaine.

Amphetamine derivatives are a class of potent drugs that act by increasing levels of dopamine, norepinephrine, and serotonin in the brain, inducing euphoria.

** Amphetamines: Amphetamine, MDMA (" Ecstasy "), Dextroamphetamine, Methamphetamine, DOM, etc.

* Serotonin, Norepinephrine, and / or Dopamine Releasers: 4-Methylaminorex ( 4-MAR ), Amphetamine, Benzphetamine, Cathine, Cathinone, Diethylcathinone, Ephedrine, Levmetamfetamine, Lisdexamfetamine, MDMA (" Ecstasy "), Methamphetamine, Pemoline, Phendimetrazine, Phenethylamine ( PEA ), Phentermine, Propylhexedrine, Pseudoephedrine, Phenylephrine, Tyramine.

Amphetamine is also used medically as an adjunct to antidepressants in refractory cases of depression.

Amphetamine and methamphetamine are indirect agonists of the catcholaminergic systems.

Born Annoying is a compilation album of Helmet's early songs, released in 1995 by their old label, Amphetamine Reptile, a. k. a. AmRep.

Amphetamine Reptile Records ( or AmRep Industries ) is a nationally renowned record label which was founded in 1986 by then-US Marine Tom Hazelmyer in Washington State, US The label is best known for its roster of noise rock artists, and its Dope, Guns ' n ' Fucking In The Streets series of compilations.

Amphetamine and related sympathomimetic medications ( such as benzphetamine ) are thought to stimulate the release of norepinephrine and / or dopamine from storage sites in nerve terminals of the lateral hypothalamic feeding center, thereby producing a decrease in appetite.

Roger Eagle, DJ at the Twisted Wheel club in Manchester, cited Amphetamine usage amongst participants as his reason for quitting the club in 1967.

* Melvins use an embossed version of the totenkopf for the " Singles 1 – 12 " compilation album which was released in 1997 through Amphetamine Reptile Records and for the CD-Single # 5.

* Advanced Techniques of Clandestine Psychedelic & Amphetamine Manufacture, an ' add-on ' for " Secrets of Methamphetamine Manufacture, provides a more advanced method of synthesizing methamphetamine using what is called " The Fester Formula ," which describes how to manufacture methamphetamine through an electric synthesis.

* Advanced Techniques of Clandestine Psychedelic & Amphetamine Manufacture.

Amphetamine and its derivatives are well known to induce psychosis, typically when abused chronically or in high doses.

Amphetamine psychosis may be purely to do with high drug usage or high drug usage may trigger an underlying vulnerability to schizophrenia.

( 1961 ) Amphetamine Psychosis.

* Japan: The use, production, and import of any medicine containing Methamphetamine or Amphetamine is prohibited.

* Thailand: Amphetamine and dextroamphetamine are classified as Type 1 Narcotics.

Amphetamine was also used legally as an aid to slimming and also as a thymoleptic before being phased out by the appearance of newer agents in the 1950s.

Lubricated Goat had its back catalog re-released via Amphetamine Reptile Records in the United States, and on Normal in Europe, before making its first American tour in mid-1989.

The relatively recent increase in the cocaine trafficking business has been largely focused on the Caribbean area.

Use of the stimulating coca leaf ( e. g. chewing it, often with slaked lime to increase bioavailability ), but not cocaine, is legal in Bolivia.

Risk factors which may increase the chance of death include obesity, prior cardiac or respiratory problems, and the use of illicit drugs such as cocaine.

These terminals are also the site of action of highly-addictive drugs such as cocaine and amphetamine, which cause a manifold increase in dopamine levels in the nucleus accumbens.

Thus, cocaine use ultimately appears to lead to an increase in the transcription of prodynorphin mRNA.

Still another study finds that giving nicotine to early adolescent rats appears to increase the reinforcing ( reward ) effects of subsequent cocaine exposure, an effect that was not seen in adult rats.

Drugs such as cocaine and methamphetamine that are dopamine agonists, which increase the pharmacological effects of dopamine, have been shown to cause uncontrollable picking in users.

Some stimulants, such as methamphetamine and cocaine, produce varying degrees of euphoric sensations, mediated by an increase in extra-cellular dopamine levels in the ventral striatum.

In Harmelin v. Michigan,, the Court upheld a life sentence without the possibility of parole for possession of 672 grams of cocaine.

The adoption of the Rockefeller drug laws gave New York State the distinction of having the toughest laws of its kind in the entire United States — an approach soon imitated by the state of Michigan, which, in 1978, enacted a " 650-Lifer Law ," which called for life imprisonment, without the possibility of parole for the sale, manufacture, or possession of at least 650 grams ( approximately 1. 45 pounds ) of cocaine or any Schedule I or Schedule II opiate.

The mind games climax when Logan reveals to Hannah that her father is a cocaine addict and then threatens her father with the possibility that he would seduce Hannah if he doesn't recant his testimony.

* February 2001: During Operation Journey Italia, RENEA took credit for destroying an Albanian-American gang, which, in partnership with the Medellín drug cartel and Italian and Albanian mafia, was exploring the possibility of turning Albania into a major international launching pad for the trafficking of cocaine.

Mixing hydrocodone with alcohol, cocaine, amphetamines, methylphenidate, benzodiazapines, barbiturates, and a number of other medications can have severe adverse reactions including but not limited to heart failure, heart attack, respiratory distress, pulmonary failure, liver or kidney failure, jaundice, amnesia, seizures, blackouts, and coma.

Also, hydrocodone can cause false indications on blood and urinalysis testing for morphine, codeine, hydromorphone and cocaine depending on usage and dosing.

Drugs that can induce psychotic symptoms include amphetamine, caffeine ( which can worsen psychotic symptoms in schizophrenia and produce olfactory hallucinations at very high doses in normal volunteers ), cannabis, cocaine, desoxypipradrol, dimethyltryptamine, alcohol ( ethanol ), inhalants, gammahydroxybutyric acid ( and its precursors gammabutyrolactone and 1, 4-butanediol ), ketamine, LSD, mephedrone and methcathinone, mescaline and other phenethylamine hallucinogens, methamphetamine, MDMA ( very rarely, likely due to different phethylamines that are sometimes sold as MDMA, or even piperazine derivatives sold as " extacy "), opiates such as heroin, phencyclidine, piperazine-based drugs, psilocybin, and anabolic steroids at high doses.

The two major sources of evidence given to support this theory are that dopamine receptor D2 blocking drugs ( i. e., antipsychotics ) tend to reduce the intensity of psychotic symptoms, and that drugs which boost dopamine activity ( such as amphetamines and cocaine ) can trigger psychosis in some people ( see amphetamine psychosis ).

Harm reduction seeks to minimize the harm that can occur through the use of various drugs, whether legal ( e. g., alcohol and nicotine ), or illegal ( e. g., heroin and cocaine ).

* intravenous injection ( see also the article Drug injection ) – morphine and heroin, less commonly other opioids or stimulants like cocaine or amphetamine, but almost every substance ( with some exceptions ) can be injected

* Crack cocaine, the freebase form of cocaine that can be smoked

In high doses and / or with prolonged use, cocaine can result in a number of negative effects as well, including irritability, anxiety, exhaustion, total insomnia, and even psychotic symptomatology.

Most of the behavioral and physiological actions of cocaine can be explained by its ability to block the reuptake of the two catecholamines, dopamine and norepinephrine, as well as serotonin.

However, recent studies show that cocaine can also cause a decrease in DAT mRNA levels.

Critics of the effort claim that it creates hardship primarily for the coca growers, many of whom are poor and have no viable alternative way to make a living, causes environmental problems, that it is not effective in reducing the supply of cocaine, in part because cultivation can move to other areas, and that any social harm created by drug abuse is only made worse by the war on drugs.

* Many illicit drugs, including amphetamines, cocaine, PCP, LSD, and MDMA can produce hyperthermia as an adverse effect.

Twenty million for the actual film, and another twenty million, you can bet, for all that cocaine for the cast and crew.

This is the basis for the so-called " Fight or Flight " response, but such stimulation can also be induced by stimulants such as ephedrine, amphetamines or cocaine.

The reason for adding levamisole to cocaine is unknown, although it can be due to their similar melting points and solubilities.

Although drug-induced changes in perception usually subside as the chemical leaves the body, long-term cocaine use can result in the chronic residual effect of micropsia.

There are also suggestions that visual distortions, such as macropsia, can be associated with cocaine use.

Other physiological factors which can cause formication and thus can sometimes lead to this condition include: menopause ( i. e. hormone withdrawal ); allergies, and drug abuse, including but not limited to cocaine and methamphetamine ( as in amphetamine psychosis ).

However, regarding psychosis itself, it is well understood that methamphetamine and cocaine use can result in methamphetamine or cocaine-induced psychosis which presents very similar symptomatology and may persist even when users remain abstinent.

Morbid jealousy can occur in a number of conditions such as chronic alcoholism, addiction to substances other than alcohol i. e. morphine, cocaine, amphetamines.