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Carbamazepine became widely used to treat bipolar disorder in the late 1980s and early 1990s, but was displaced by sodium valproate in the 1990s.
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Carbamazepine and widely
Carbamazepine was approved by the US Food and Drug Administration as a bipolar disorder treatment in 2005, but had been widely used previously.
Carbamazepine and used
Carbamazepine ( CBZ ) is an anticonvulsant and mood-stabilizing drug used primarily in the treatment of epilepsy and bipolar disorder, as well as trigeminal neuralgia.
Carbamazepine is typically used for the treatment of seizure disorders and neuropathic pain.
Carbamazepine has a potential for drug interactions ; caution should be used in combining other medicines with it, including other antiepileptics and mood stabilizers.
* Carbamazepine, or Tegretol, has been used as a mood stabilizer and is accepted treatment for bipolar disorder.
Carbamazepine and treat
Carbamazepine was first marketed as a drug to treat trigeminal neuralgia ( formerly known as tic douloureux ) in 1962.
Carbamazepine and bipolar
Carbamazepine is effective in treating manic episodes, with some evidence it has greater benefit in rapid-cycling bipolar disorder, or those with more psychotic manic symptoms or a more schizoaffective clinical picture.
Carbamazepine would be studied for bipolar disorder throughout the 1970s.
Carbamazepine and disorder
* Carbamazepine is an approved treatment for manic depression and convulsions, but has side effects useful in treating attention-deficit hyperactivity disorder ( ADHD ), schizophrenia, phantom limb syndrome, paroxysmal extreme pain disorder, neuromyotonia, and post-traumatic stress disorder.
Carbamazepine and was
Carbamazepine was discovered by chemist Walter Schindler at J. R. Geigy AG ( now part of Novartis ) in Basel, Switzerland, in 1953.
The initial autopsy report describes the drug as Carbamazepine, and that dosage was found to be at sub-therapeutic level.
Carbamazepine was approved in the United States for the treatment of adult epilepsy in 1974.
Carbamazepine and by
Carbamazepine increases the risk of developing lupus by 88 % ( odds ratio of 1. 88 ), with the effect possibly restricted to women.
Carbamazepine and sodium
Carbamazepine stabilizes the inactivated state of Voltage-gated sodium channels, making fewer of these channels available to subsequently open.
Carbamazepine and .
Carbamazepine preparations typically greatly decrease a person's alcohol tolerance.
Carbamazepine may aggravate juvenile myoclonic epilepsy, so it is important to uncover any history of jerking, especially in the morning, before starting the drug.
Carbamazepine, as a CYP450 inducer, may increase clearance of many drugs, decreasing their blood levels.
Carbamazepine also increases the metabolism of the hormones in birth control pills and can reduce their effectiveness, potentially leading to unexpected pregnancies.
Carbamazepine can enter the environment through discharge of wastewater, and has also been shown to persist and accumulate in the organic components of soil and sludge.
Carbamazepine exhibits autoinduction: it induces the expression of the hepatic microsomal enzyme system CYP3A4, which metabolizes carbamazepine itself.
Carbamazepine has also been shown to potentiate GABA receptors made up of alpha1, beta2, gamma2 subunits.
Carbamazepine is a dibenzazepine.
* Carbamazepine overview from PsychEducation. org
* Carbamazepine ( Tegretol ) – CBC should be monitored, as carbamazepine can lower white blood cell count.
became and widely
Even as he became widely known as a professional killer, nearly every cowboy and rancher in Wyoming seemed proud to call him a friend.
In short order, the general history became his most popular work and has remained, aside from his later Social history, the work most widely favored by the public.
Analysis of variance became widely known after being included in Fisher's 1925 book Statistical Methods for Research Workers.
Due to Pope Sylvester II's reintroduction of the abacus with very useful modifications, it became widely used in Europe once again during the 11th century
Because they often exhibit a combination of high strength and low weight, these alloys became widely used in many forms of industry, including the construction of modern aircraft.
King became widely influential and continues to be used.
The European acceptance of the numerals was accelerated by the invention of the printing press, and they became widely known during the 15th century.
Ayahuasca became more widely known when the McKenna brothers published their experience in the Amazon in True Hallucinations.
At first selling slowly, it rapidly became a lasting success, and its appeal to English musicians had helped to make it widely known before World War I, when its themes struck a powerful chord with English readers.
The precise formation mechanism is not known for certain, but the most widely accepted hypothesis suggests that the edge of the Cathedral Formation reef became detached from the rest of the reef, slumping and being transported some distance — perhaps kilometers — away from the reef edge.
His Fender Precision Bass, introduced in 1951, became a widely copied industry standard.
By the turn of the century, cycling clubs flourished on both sides of the Atlantic, and touring and racing became widely popular.
Kernighan's name became widely known through co-authorship of the first book on the C programming language with Dennis Ritchie.
Another important use of aircraft came with the development of the helicopter, which first became heavily used during the Vietnam War, and still continues to be widely used today to transport and augment ground forces.
" After wearing glasses for a while, his eyes became adjusted to the lenses, and at that point he became nearsighted and really did need glasses, which would years later establish John as one of the most famous " four-eyes " in rock and roll, though Holly is widely considered to be the first.
The work was translated into English the following year, and with the cholera epidemic happening at that time, " The Black Death in the 14th century " gained widespread attention and the terms Schwarzer Tod and Black Death became more widely used in the German-and English-speaking worlds, respectively.
Their works became more widely known in Europe in the twelfth and thirteenth centuries, beginning with the Latin translation of Jābir ’ s Kitab al-Kimya in 1144.
Eventually this song became " Bro goz va zadoù " (" Old land of my fathers ") and is the most widely accepted Breton anthem.
Clementi's sonatas for the piano circulated widely, and he became the most successful composer in London during the 1780s.
From a popular perspective, the term Chicano became widely visible outside of Chicano communities during the American civil rights movement.
The Minister of Fuel and Power, Emanuel Shinwell, became a scapegoat for the crisis and was widely blamed for failing to ensure adequate coal stocks, and soon resigned from his post.
The steel-string and electric guitars characteristic to the rise of rock and roll in the post-WWII era became more widely played in North America and the English speaking world.
Cretin became a medical term in the 18th century, from an Alpine French dialect prevalent in a region where persons with such a condition were especially common ( see below ); it saw wide medical use in the 19th and early 20th centuries, and then spread more widely in popular English as a markedly derogatory term for a person who behaves stupidly.
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