Despite extensive attempts to obtain highly pure reagents, serious difficulty was experienced in obtaining reproducible rates of reaction.

Despite two coup attempts in the following three months, including one by Abeid, Bacar ’ s government remained in power, and was apparently more willing to negotiate with Comoros.

Despite attempts to protect the town through quarantine, eight known cases of smallpox appeared in Boston by May 27, and by mid-June, the disease was spreading at an alarming rate.

Despite Bismarck's attempts to play the role of an " honest broker " at the Congress of Berlin, Russo-German relations deteriorated following the conference.

Despite Guy Montag's attempts to break her from the spell society has on her, Mildred continues to be shallow and indifferent.

Despite some military attempts by the Spanish to retake it in the 18th century, most notably in the Great Siege of 1779 – 1783, the Rock has remained under British control ever since.

Despite his attempts at neutrality, George William was forced by Gustavus Adolphus to join the Protestant forces in 1631.

Despite victories at Dupplin Moor and Halidon Hill, in the face of tough Scottish resistance led by Sir Andrew Murray, the son of Wallace's comrade in arms, successive attempts to secure Balliol on the throne failed.

Despite a friendship with Albert Spalding, Chadwick was scornful of the attempts to have Abner Doubleday declared the inventor of baseball.

Despite his self-professed attempts to treat Jamiroquai as a band, Kay has always been at the forefront of the band.

Despite coup attempts in 1980, 1983, and 1988, Gayoom's popularity remained strong, allowing him to win three more presidential terms.

Despite her many attempts, Mei is unable to show her family Totoro's tree.

Despite attempts to silence critics, Bismarck remained a largely unpopular politician.

Despite Gorbachev's attempts to discourage Russia's electorate from voting for him, Yeltsin was popularly elected as president, handily defeating five other candidates with more than 57 percent of the vote.

Despite further attempts, the Muslims were unable to conquer Pelayo's mountain stronghold.

Despite attempts to improve its agricultural base and emphasize locally manufactured products and indigenous materials, Seychelles continues to import 90 % of what it consumes.

Despite French attempts to maintain control by encouraging sectarian divisions and isolating urban and rural areas, the revolt spread from the countryside and united Syrian Druze, Sunnis, Shiites, Allawis, and Christians.

Despite repeated attempts by family members and others to have it expunged, his conviction has never been overturned.

Despite its elegance, Montague grammar was limited by the context-dependent variability in word sense, and led to several attempts at incorporating context, such as:

Despite attempts at reorganization of the Air Board, the earlier problems failed to be completely resolved.

Despite numerous successful campaigns and raids by the Roman army over the Rhine in the years after the battle, the Romans were to make no more concerted attempts to conquer and permanently hold Germania beyond the river.

Despite white attempts to control independent black congregations, especially after the Nat Turner Uprising of 1831, a number of black congregations managed to maintain their separation as independent congregations in Baptist associations.

Despite her attempts to remain out of the public eye, she was falsely accused in the libelles of having an affair with the commander of the Garde Nationale, the marquis de La Fayette.

Despite various attempts to get her out, such as the Carnation Plot in September, Marie Antoinette refused when the plots for her escape were brought to her attention.

Despite the destruction wrought on the countryside, the city castle held out in spite of repeated attempts over twelve days to take it, and the Turks left the island unsuccessfully because of poor logistics and an epidemic that decimated their ranks.

Despite suffering heavy defeats against the West Indies during the 1980s, England continued to do well in the Ashes.

Despite the much-vaunted capabilities, the Phoenix was rarely used in combat, with only two confirmed launches and no confirmed targets destroyed in US Navy service, though a large number of kills were claimed by Iranian F-14s during the Iran – Iraq War.

Despite the absence of a Benedictine order, since most monasteries founded during the Middle Ages adopted the Rule of St Benedict, it became the standard for Western Monasticism.

Despite the term blitzkrieg being coined by journalists during the Invasion of Poland of 1939, historians Mathew Cooper and J. P Harris generally hold that German operations during it were more consistent with more traditional methods.

Despite a hotly contested South Carolina primary, none of the candidates appeared on the platform of BJU's Founders ' Memorial Amphitorium during the 2008 election cycle.

Despite being well out of playoff contention the Cubs went 24 – 13 under Quade, the best record in baseball during that 37 game stretch and was hired as manager on October 19.

Despite financial difficulties, Caligula embarked on a number of construction projects during his reign.

Despite the drawbacks, sustained artillery fire proved deadly during the engagement, especially during the French cavalry attack.

Despite the change to indirect fire, cannon proved highly effective during World War I, directly or indirectly causing over 75 % of casualties.

Despite occasional entanglements with European Powers such as the War of 1812 and the 1898 Spanish-American War, U. S. foreign policy was marked by steady expansion of its foreign trade and scope during the 19th century, and it maintained its policy of avoiding wars with and between European powers.

Despite the recession of the late 1950s, the company sold $ 94, 000 worth of these modules during 1958 alone, turning a profit at the end of its first year.

Despite the relative cultural monopoly of the capital and the centralized government, the divided geography of the country allowed distinct rural dialects to flourish during the centuries.

Despite his Conn Smythe Trophy in the 1997 playoffs, Mike Vernon had been replaced as the regular Wings goaltender during the season with the younger Chris Osgood.

Despite David's reputation, he was more fiercely criticized right after his death than at any point during his life.

Despite the Roman victories at sea, the Roman Republic lost countless ships and crews during the war, due to both storms and battles.

Despite lacking a university education, Bessel was a major figure in astronomy during his lifetime.

Despite reports that there had been an influx of arms in the weeks leading up to the election and reports of some ' disturbances during campaigning ' - including attacks on the presidential palace and the Interior Ministry by as-yet-unidentified gunmen-European monitors labelled the election as " calm and organized ".

Despite the arguably greater architectural inventiveness of Borromini and Cortona, Bernini's artistic pre-eminence, particularly during the reigns of popes Urban VIII ( 1623 – 1644 ) and Alexander VII ( 1655 – 1665 ), meant he was able to secure the most important commission in the Rome of his day, St. Peter's Basilica.

Despite mechanization, production difficulties related to humidity control, especially during the pressing, were still present in the late 19th century.

Despite this reputation, during his career, he oversaw more performances honored with the Academy Award for Best Actor than any other director: James Stewart in The Philadelphia Story ( 1940 ), Ronald Colman in A Double Life ( 1947 ), and Rex Harrison in My Fair Lady ( 1964 ).

Despite his efforts to rise above the rank of private — he even called upon Frank Capra to intercede on his behalf — he never achieved officer's status or any commendations during his six months of service.

Despite a long history of warfare between Britain and Spain, Vancouver maintained excellent relations with his Spanish counterparts and even feted a Spanish sea captain aboard his ship during his 1792 trip to the Vancouver region.

Despite the fact that Parsons only contributed two new songs to the album (" In My Hour of Darkness ", " Return of the Grievous Angel "), Parsons was highly enthused with his new sound and seemed to have finally adopted a serious, diligent mindset to his musical career, eschewing most drugs and alcohol during the sessions.