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Dextromethorphan has been noted to slow the development of tolerance to opioids and exert additional analgesia by acting upon the NMDA receptors ; some analgesics such as methadone and ketobemidone and perhaps piritramide have intrinsic NMDA action.
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Dextromethorphan and has
Dextromethorphan has powerful dissociative properties when administered in doses well above those considered therapeutic for cough suppression.
Dextromethorphan, a common antitussive often found in cough medicines, has been shown to cause vacuolization in rats ' brains when administered at doses of 75 mg / kg.
Dextromethorphan and by
Robitussin contains an expectorant ( Guaifenesin ); Robitussin DM adds a cough suppressant ( Dextromethorphan ) to the expectorant ( Guaifenesin ); Robitussin CF is a cold formula that adds an expectorant and a nasal decongestant ; there is a nighttime-relief formula that uses a different cough suppressant, and there is a formula with codeine, available by prescription only.
Dextromethorphan and NMDA
Dextromethorphan and ;
Dextromethorphan and have
Dextromethorphan is still excluded from the CSA ( as of 2010 ); however, officials have warned that it could still be added if increased abuse warrants its scheduling.
Dextromethorphan and .
Dextromethorphan ( DXM ), a common active ingredient found in many over-the-counter cough suppressant cold medicines, is used as a recreational drug for its often euphoric dissociative effects.
Dextromethorphan was excluded from the Controlled Substances Act ( CSA ) of 1970 and was specifically excluded from the Single Convention on Narcotic Drugs.
** Others: Brompheniramine, Chlorpheniramine, Cocaine, Cyclobenzaprine, Dextromethorphan ( DXM ), Ketamine, MDPV, Nefazodone, Phencyclidine ( PCP ), Pheniramine, Sibutramine, Trazodone.
Dextromethorphan ( DXM ) may be modestly effective in decreasing cough in adults with viral upper respiratory infections.
It can also be a side effect of the anti-epileptic drugs Phenytoin and Zonisamide, and the anti-convulsant drug Lamotrigine, as well as the hypnotic drug Zolpidem and the dissociative drugs Ketamine and Dextromethorphan.
* Dextromethorphan ( DXM ), the active ingredient of cough medications like Robitussin DM, is abused for its effects which are similar to ketamine and PCP.
has and been
As it is, they consider that the North is now reaping the fruits of excess egalitarianism, that in spite of its high standard of living the `` American way '' has been proved inferior to the English and Scandinavian ways, although they disapprove of the socialistic features of the latter.
In what has aptly been called a `` constitutional revolution '', the basic nature of government was transformed from one essentially negative in nature ( the `` night-watchman state '' ) to one with affirmative duties to perform.
For lawyers, reflecting perhaps their parochial preferences, there has been a special fascination since then in the role played by the Supreme Court in that transformation -- the manner in which its decisions altered in `` the switch in time that saved nine '', President Roosevelt's ill-starred but in effect victorious `` Court-packing plan '', the imprimatur of judicial approval that was finally placed upon social legislation.
Labor relations have been transformed, income security has become a standardized feature of political platforms, and all the many facets of the American version of the welfare state have become part of the conventional wisdom.
Historically, however, the concept is one that has been of marked benefit to the people of the Western civilizational group.
In recent weeks, as a result of a sweeping defense policy reappraisal by the Kennedy Administration, basic United States strategy has been modified -- and large new sums allocated -- to meet the accidental-war danger and to reduce it as quickly as possible.
Even though in most cases the completion of the definitive editions of their writings is still years off, enough documentation has already been assembled to warrant drawing a new composite profile of the leadership which performed the heroic dual feats of winning American independence and founding a new nation.
Madison once remarked: `` My life has been so much a public one '', a comment which fits the careers of the other six.
Thus we are compelled to face the urbanization of the South -- an urbanization which, despite its dramatic and overwhelming effects upon the Southern culture, has been utterly ignored by the bulk of Southern writers.
But the South is, and has been for the past century, engaged in a wide-sweeping urbanization which, oddly enough, is not reflected in its literature.
An example of the changes which have crept over the Southern region may be seen in the Southern Negro's quest for a position in the white-dominated society, a problem that has been reflected in regional fiction especially since 1865.
In the meantime, while the South has been undergoing this phenomenal modernization that is so disappointing to the curious Yankee, Southern writers have certainly done little to reflect and promote their region's progress.
Faulkner culminates the Southern legend perhaps more masterfully than it has ever been, or could ever be, done.
The `` approximate '' is important, because even after the order of the work has been established by the chance method, the result is not inviolable.
But it has been during the last two centuries, during the scientific revolution, that our independence from the physical environment has made the most rapid strides.
In the life sciences, there has been an enormous increase in our understanding of disease, in the mechanisms of heredity, and in bio- and physiological chemistry.
Even in domains where detailed and predictive understanding is still lacking, but where some explanations are possible, as with lightning and weather and earthquakes, the appropriate kind of human action has been more adequately indicated.
The persistent horror of having a malformed child has, I believe, been reduced, not because we have gained any control over this misfortune, but precisely because we have learned that we have so little control over it.
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