During the winter of 2010 / 11, which was quite severe compared to those of the last decades, the maximum ice cover was 315 000 km < sup > 2 </ sup >, which was reached on 25 February 2011.

During the Cold War dog tags were issued to everyone, often soon after birth, since the threat of total war also meant the risk of severe civilian casualties.

During the 17th and 18th centuries, Easter Island experienced severe erosion due to deforestation and unsustainable agricultural practices.

During these wars the Finns suffered 90, 000 casualties and inflicted severe casualties on the Russians ( 120, 000 dead in the Winter War and 200, 000 in the Continuation War ) compared to other nations such as Poland.

During the last three weeks of shooting, Fellini experienced the first signs of severe clinical depression.

During 1975, two years after the military coup that ended the government of Salvador Allende, the economy of Chile experienced a severe crisis.

* 1971 – During a severe thunderstorm over Washington state, a hijacker calling himself Dan Cooper ( AKA D. B. Cooper ) parachutes from a Northwest Orient Airlines plane with $ 200, 000 in ransom money.

During what is known as the Little Ice Age, Innocent VIII, in his papal bull Summis desiderantes ( 5 December 1484 ) instigated severe measures against magicians and witches in Germany.

During the 1970s, severe budget constraints challenged the university's physical development ; but, in the 1980s, the university received increased grants for research in the social and physical sciences.

** West Ice accidents: During a severe storm in the West Ice, east of Greenland, 78 seal hunters on 5 Norwegian seal hunting vessels perish without a trace.

** During a severe thunderstorm over Washington, a man calling himself D. B. Cooper parachutes from the Northwest Orient Airlines plane he hijacked, with US $ 200, 000 in ransom money, and is never seen again ( as of March 2008, this case remains the only unsolved skyjacking in history ).

During the decisive battle before the walls he suffers a severe defeat, and only the heavy loss of Visigoths makes king Theodoric I decide to agree to a provisional restoration of the status quo.

During the Second World War Milan suffered severe damage from British and American bombings.

** During this year's Atlantic hurricane season, probably the most severe of the pre-1600 seasons, at least eight intense hurricanes occur.

During the travel south, however, Otto III suffered a sudden and severe fever.

During this phase, organ dysfunction and severe bleeding, typically from the gastrointestinal tract, may occur.

During religious conflict in 16th and 17th century Ireland severe legal penalties were prescribed against practicing Roman Catholics.

During the summer of 2006, a severe drought caused the Iguazu River to become diminished, reducing the amount of water flowing over the falls to until early December.

During the 17-year pontificate of Zephyrinus, the young Church endured severe persecution under the Emperor Severus until his death in the year 211.

During severe illness, a tube may be placed in the throat ( a procedure known as a tracheostomy ) to enable breathing supported by a ventilator.

During the events of Dark Empire, the New Republic suffers severe setbacks, losing most of its worlds, as well as Luke Skywalker to the dark side.

During the late eighties and early nineties a severe economic crisis emerged stemming from poor government oversight and overspending.

During the struggle at Boggart Hole Clough, Richard Pankhurst began to experience severe stomach pains.

During this period Vliet suffered severe anxiety attacks that made him convinced that he was having a heart attack, probably exacerbated by his heavy LSD use and the fact that his father died of heart failure a few years earlier.

During her time away she became seriously ill with typhus ( she had suffered from severe bronchitis and tuberculosis as a young woman ).

During fetal development, since bones and thus the bone marrow develop later, the liver functions as the main haematopoetic organ.

During 1977, Czernilofsky published research that used affinity labeling to identify tRNA-binding sites on rat liver ribosomes.

During this assisted escape ( from a research institute Baader was visiting rather than a prison ), a 64-year old librarian was shot ( several times with a pistol, resulting in critical liver damage ) and two law enforcement officers were wounded.

During prolonged fasting or starvation, acetyl-CoA in the liver is used to produce ketone bodies instead, leading to a state of ketosis.

During the Ming Dynasty ( AD 1368 – 1644 ), physician Wu Juei wrote that the mushroom could be used not only as a food but as a medicinal mushroom, taken as a remedy for upper respiratory diseases, poor blood circulation, liver trouble, exhaustion and weakness, and to boost qi, or life energy.

During this time he lost a rib and part of his liver and had to be hospitalized for eleven months.

During the acute stage of the infection, the liver enzyme alanine transferase ( ALT ) is present in the blood at levels much higher than is normal.

During the night, bone marrow went into Peterson's bloodstream through the fractures, forming fat globules on his major organs including lungs, liver and brain.

During the final years of the 1940s, although lacking financial resources and operating with very low-cost teams, Leloir's successful experiments would reveal the chemical origins of sugar synthesis in yeast as well as the oxidation of fatty acids in the liver ; together with J. M. Muñoz, he produced an active cell-free system, a first in scientific research.

During the late 1870s, Empress Dowager Cixi became ill from liver complaints, so Empress Dowager Ci ' an had to rule on her own.

During Idul Fitri in Indonesia, ketupat is often served with either opor ayam ( chicken in coconut milk ), chicken or beef curry, rendang, sambal goreng ati ( spicy beef liver ), krecek ( buffalo or beef skin dish ), or sayur labu Siam ( chayote soup ).

During Laparoscopic Cholecystectomy, gallbladder perforation can occur due to excessive traction during retraction or during dissection from the liver bed.

During production of Shindo's 1995 film A Last Note, Nobuko Otowa was diagnosed with liver cancer.

During that time, it expanded the traditional role of the consumer programme from simply exposing faulty washing machines and dodgy salesmen, to investigating life and death issues such as a campaign for more organ donors, featuring Ben Hardwick, a two-year-old dying of liver disease, whose only hope was a transplant, and the investigation of a boarding school owned by a paedophile, who employed two paedophile teachers.

During embryogenesis it directs the migration of hematopoietic cells from foetal liver to bone marrow and the formation of large blood vessels.

During surgery on April 4, doctors found cancer in her liver and pancreas.

During this time, they feed on liver cells and blood.

During the acute phase, the liver redirects protein synthesis, up-regulating certain proteins and down-regulating others.

During his MMA career he became known for two particular things: his fondness of liver shots and his habit of doing a jumping split after winning a fight.

During feeding, the mosquito injects saliva to prevent blood clotting ( along with sporozoites ), thousands of sporozoites are inoculated into human blood ; within a half-hour the sporozoites reach the liver.

During his time, the common view was that blood originates in the liver then travels to the right ventricle, then on to the organs of the body ; another contemporary view was that blood is filtered through the diaphragm where it mixes with the air coming from the lungs.

During his second term, Governor Casey was diagnosed with Appalachian familial amyloidosis, a rare and usually fatal liver disorder.

During periods of fasting, fatty acids are also an important energy source for the liver and other tissues.