However, after enough carbamazepine has been presented to the liver tissue, the CYP3A4 activity increases, speeding up drug clearance and shortening the half-life.

( However, the colloquial form written as em ", as in " up and at ' em ", may well represent a spoken survival of " hem " rather than a shortening of the Norse-derived " them ".

However, because of DNA replication mechanisms, oxidative stress, and, because TERT expression is very low in many types of human cells, the telomeres of these cells shrink a little bit every time a cell divides, although, in other cellular compartments that require extensive cell division, such as stem cells and certain white blood cells, TERT is expressed at higher levels and telomere shortening is partially or fully prevented.

However, shortening the stirrup until the rider feels they will not lose the stirrup is counterproductive ; the goal of correct equestrianism is to make maximum use of the leg.

However, the practicality of this solution is limited by the resulting high recharge current through the equivalent series resistance ( ESR ) of the capacitors ; the ESR will dissipate some of the recharge current, generating heat within the capacitors and potentially shortening their lifetime.

However, this shortening of / o :/ / ø :/ / a :/ / æ :/ is not general.

However in unilateral cases ( e. g. post traumatic ), there may be shortening, leading to a short limb gait characterised by limp which is seen as a vertical dip on the affected side during the stance phase ( as opposed to a lurch characterised in a Trendelenburg gait ).

However, the novel depicted the process as shortening the star's lifespan precipitously rather than extending it.

However, the propeller required shortening before trials commenced because of its " greatly excessive vibration.

However, on a rotating planet, it must also be taken into account that the receiver moves during the transit time of the signal, shortening or lengthening the transit time compared to what it would be in the situation of a non-rotating planet.

However, the interconnects ( metal and poly pitch ) continue to shrink, thus reducing chip area and chip cost, as well as shortening the distance between transistors, leading to higher performance devices of greater complexity when compared with earlier nodes.

However, after long discussion among students and staff, the school decided not to adopt the schedule proposed by the current principal, due to other problems in the proposed schedule, such as shortening of Family Group and Committee meetings and difficulty in scheduling some classes.

However, the CCC is still firmly in control of the town's political structure-all 16 of the elected officials currently serving Glen Ridge were nominated by the CCC.

However, the majority of the park facilities were not constructed until the 1930s by the Civilian Conservation Corps ( CCC ) and the Works Progress Administration ( WPA ).

However, the fact that two settlements came into existence very close together creates further difficulties.

However, revoking a key now requires both Alice and Bob to be available, and this creates a problem of reliability.

However, SAMI files and Macintosh self mounting images also use, which creates some ambiguity at first glance.

However, unlike strategy, which inherently creates its own autonomous space: “ A tactic is a calculated action determined by the absence of a proper locus.

However, some recreational ski boats will have the motor placed in the back of the boat ( v-drive ), which creates a bigger wake.

However, with direct current, because the electrode only creates the arc and does not provide filler material, a positively charged electrode causes shallow welds, while a negatively charged electrode makes deeper welds.

However, one could easily modify the classic statement as follows: " An omnipotent being creates a universe which follows the laws of Aristotelian physics.

However, the ambiguity this creates between the two versions, while coincidental, is in keeping with the nature of the character and Deighton's theme of agents losing sight of their original lives.

However, being a god, he is quickly able to break free and creates more havoc, razing the palace of Pentheus to the ground in a giant earthquake and fire.

However, due to Spike handing him the wrong ingredients, Bushroot accidentally creates a gigantic potato that feeds on the blood of non-plants.

However, the use of three-character extensions under Microsoft Windows has continued, originally for backward compatibility with older versions of Windows and now by habit, along with the problems it creates.

However, the boundary layer would separate early, as the pressure gradient switched from favorable ( pressure decreasing in the flow direction ) to unfavorable ( pressure increasing in the flow direction ), creating a large region of low pressure behind the ball that creates high form drag.

However, Say's Law does not state that production creates a demand for the product itself, but rather a demand for " other products to the full extent of its own value.

However, unlike a blade that has been evenly heated and differentially quenched, flame hardening creates a heat-affected zone.

However, high humidity outdoors creates the need for careful attention to humidity levels indoors.

However the earphone's higher resistance, in parallel with its capacitance of around 9 pF, creates a low pass filter which removes the higher audio frequencies, distorting or eliminating the sound.

However, since the island creates an area of dead water behind it with no wind ( hence " still behind "-still or stopped being an alternative translation of mati ) it may be as simple as this — less romantic perhaps, but believable from a nautical viewpoint.

However, the Prince realizes too late that killing the Empress is what creates the sands, and hence he becomes the architect of his own fate.

However this creates an inconsistency ( paradox ) in which the egg has no origin.

However, he claims that his Principle of Harmony, according to which God creates the best and most harmonious world possible, dictates that the perceptions ( internal states ) of each monad " expresses " the world in its entirety, and the world expressed by the monad actually exists.

However, this is only a myth, as the current half dome, which creates the effect, was not installed until 1902.

However, these concepts are controversial because muzzle blast creates broadband noise rather than pure tones, and phase cancellation in particular is therefore extremely difficult ( if not impossible ) to achieve.

However, before the prince can deal the killing blow, Aku creates a time portal and sends his opponent into the distant future, anticipating that he would be able to amass sufficient power to deal with the Samurai later.

However this creates problems of its own, because many of the most interesting phenomena in animal cognition are only likely to be demonstrated in a social context, and in order to train and demonstrate them, it is necessary to build up a social relationship between trainer and animal.

However, it is important to trace the philosophy of the French Revolution to its sources to understand the common democratic origin of individualism and socialism and the influence of the latter on the former.

However, Biblical scholars frequently attested to its numerous inaccuracies, as old manuscripts were uncovered and scholarship advanced.

However, the East Providence Rescue Squad made its way through to my home in time of desperation.

However, it seems axiomatic that the government has an obligation `` to exercise its mandate reasonably, equitably and with full regard for the disruptions which it inevitably causes ''.

However, this Court put to one side without consideration the Government's appeal from the dismissal of its Sherman Act allegations.

However, its modern one-story layout is designed to increase our production capacity, permit more efficient manufacturing, and substantially reduce current repair and maintenance costs.

However, when labor disputes arise, its provisions come clearly into play.

However, the Federal Court held that since the State had accepted the provisions of the Wagner-Peyser Act into its own Code, and presumably therefore also the regulations, it was now a State matter.

However, this inaugural feast did its sponsors no good whatever.

However much football has been over-emphasized, the public likes to measure its collegiate favorites by the scoreboard, so, while Yale need never give its record a thought again since outscoring its opponents 694 to 0 in the season of 1888, Dartmouth had to wait until its championship team of 1925 for national recognition.

However, even if the latent demand for demythologization is not nearly as widespread as we are claiming, at least among the cultured elements of the population there tends to be an almost complete indifference to the church and its traditional message of sin and grace.

However, it did not come into general use until Joseph Greenberg ( 1963 ) formally proposed its adoption.

However, with an international language with wide variations in its dialects, such as English, it would be impossible to represent the language in all its variations with a single phonetic alphabet.

However, in some areas the aardwolf is hunted for its fur.

However, since Anatolia is now often considered to be synonymous with Asian Turkey, its eastern and southeastern borders are widely taken to be the Turkish borders with the neighboring countries, which are Georgia, Armenia, Iran, Iraq and Syria, in clockwise direction.

However it is in its proper sense, in which it indicates national character and the subjection due to that character, that the word is more important.

However, years of activism, and fighting for the Republican side of the Spanish Civil War have left him disillusioned .</ br > When the plague epidemic is virtually over, Tarrou becomes one of its last victims, but puts up a heroic struggle before dying.

However a comparable performing digital system is more complex and can require more bandwidth than its analog counterpart.

However, the dispute over the Armenian Genocide and the recent war over Nagorno-Karabakh have created tense relations with two of its immediate neighbors, Azerbaijan and Turkey.

However, its describers claim that other features of its skeleton reflect adaptation to bipedalism on the ground as well.