By 1599 the last Metropolitan, Abraham, had died, and the Archbishop of Goa, Aleixo de Menezes, had secured the submission of the young Archdeacon George, the highest remaining representative of the native church hierarchy.

In 1599 under Aleixo de Menezes the Synod of Diamper converted the Syriac Saint Thomas Christians ( of the Eastern faith ) of Kerala to the Roman Catholic Church under the excuse that they allegedly practiced Nestorian heresy.

* 1565 – Cornelis de Houtman, Dutch explorer ( d. 1599 )

* 1658 – Witte Corneliszoon de With, Dutch naval officer ( b. 1599 )

* April 2 – Cornelis de Houtman, Dutch explorer ( d. 1599 )

de: 1599

* November 8 – Witte Corneliszoon de With, Dutch naval officer ( b. 1599 )

Like Gesner, Ulisse Aldrovandi, an encyclopedic naturalist began a 14-volume natural history with three volumes on birds, entitled ornithologiae hoc est de avibus historiae libri XII which was published from 1599 to 1603.

Henry's marriage to Margaret, which had produced no heir, was annulled in 1599 and he married Marie de Medici, the niece of the grand duke of Tuscany.

Some other interesting buildings are the town hall ( Stadhuis ), a 16th-century building that was badly damaged by a fire in 1929 but has its Renaissance façade designed by Lieven de Key still standing ; the Gemeenlandshuis van Rijnland ( 1596, restored in 1878 ); De Waag ( weigh house in Dutch ), built by Pieter Post ; the former court-house ( Gerecht ); a corn-grinding windmill, now home to a museum ( Molen de Valk ) ( 1743 ); the old gymnasium ( Latijnse School ) ( 1599 ) and the city carpenter's yard and wharf ( Stadstimmerwerf ) ( 1612 ), both built by Lieven de Key ( c. 1560 – 1627 ).

Title page of the book Guzmán de Alfarache ( 1599 )

Another early example is Mateo Alemán's Guzmán de Alfarache ( 1599 ), characterized by religiosity.

Diego Rodríguez de Silva y Velázquez (; baptised June 6, 1599 – August 6, 1660 ) was a Spanish painter who was the leading artist in the court of King Philip IV.

Gabrielle d ' Estrées, Duchess of Beaufort and Verneuil, Marchioness of Monceaux (; 1573 – 10 April 1599 ) was a French mistress of King Henry IV of France, born at either the Château de la Bourdaisière in Montlouis-sur-Loire, in Touraine, or at the château de Cœuvres, in Picardy.

In 1599, he published the first part of Guzmán de Alfarache, a celebrated picaresque novel which passed through no less than sixteen editions in five years ; a spurious sequel was issued in 1602, but the authentic continuation did not appear until 1604.

* the Hoop (" Hope "), under Jacques Mahu († 1598 ), expedition leader, succeeded by Simon de Cordes († 1599 ), and finally, Jan Huidekoper,

* the Trouw (" Loyalty "), under Jurriaan van Boekhout († 1599 ), and finally, Baltazar de Cordes,

Heracles beating the Centaur Nessus ( 1599 ) is also a conscious tour de force.

both were founded in 1639 by French nun Marie de l ' Incarnation ( 1599 – 1672 ) alongside laywoman Marie-Madeline de Chauvigny de la Peltrie ( 1603 – 1671 ) and are the first Canadian institutions to have music as part of the curriculum.

* Lorenzo de ' Medici ( 1599 – 1648 ) died unmarried.

* Alonso de Ribera ( Chile 1599 – 1617 )

The Udayamperoor Synod ( 1599 ) was a major attempt by the Portuguese Archbishop Menezes to Latinize the Syrian rite.

The only case in which an ancient Eastern rite has been wilfully romanized is that of the Uniat Malabar Christians, where it was not Roman authority but the misguided zeal of Alexius de Menezes, Archbishop of Goa, and his Portuguese advisers at the Synod of Diamper ( 1599 ) which spoiled the old Malabar Rite.

The only case in which an ancient Eastern rite has been wilfully romanized is that of the Malabar Christians, where it was not Roman authority but the misguided zeal of Alexius de Menezes, Archbishop of Goa, and his Portuguese advisers at the Synod of Diamper ( 1599 ) which spoiled the old Malabar Rite.

* Matthew Hutton, Bishop of Durham & Archbishop of York, 1596 – 1599

In 1599 Archbishop Whitgift made a raid on contemporary satire in general, and among other books the tracts of Harvey and Nashe were destroyed, and it was forbidden to reprint them.

The only son of Sir Thomas Windebank of Hougham, Lincolnshire, who owed his advancement to the Cecil family, Francis entered St John's College, Oxford, in 1599, coming there under the influence of the Archbishop of Canterbury, William Laud.

The Archbishop of Canterbury John Whitgift and the Bishop of London Richard Bancroft banned the Scourge and had it publicly burned, along with copies of works by other satirists, on 4 June 1599.

He was in turn succeeded in 1592 by his son Richard Thornes, who in 1599 bought a third part of the Manor of Ruyton from George Younge, Esq., possibly the heir of Thomas Younge, Archbishop of York, who had bought the manor in 1567 from the Earl of Arundel and others.

Abraham Andersson, usually known under the Latin form of his name, Abrahamus Andreæ Angermannus or just Abraham Angermannus ( died in October 1607 ) was the fourth Lutheran Archbishop of Uppsala in the Church of Sweden from 1593 to 1599.

Nicolaus Olai Bothniensis ( born about 1550 in Piteå, died 18 May 1600 ) was Archbishop of Uppsala in the Church of Sweden 1599 – 1600.

* 1599 – Nine Years ' War: Battle of Curlew Pass – Irish forces led by Hugh Roe O ' Donnell successfully ambush English forces, led by Sir Conyers Clifford, sent to relieve Collooney Castle.

The need to find a scapegoat for calamities such as the Black Plague, which claimed 2, 000 area residents ( 25 % of the city population ) in 1564, led to an escalation in witch-hunting that reached its peak in 1599.

The ambassador Husain Ali Beg led the first Persian embassy to Europe ( 1599 – 1602 ).

This led to the creation of the Muyejebo ( 무예제보, Hanja: 武藝諸譜 ) in 1599 by Han Gyo, who had studied the use of several weapons with the Chinese army.

On 15 August 1599, the Battle of Curlew Pass between English and Irish forces was fought in the Curlew mountains during the Nine Years ' War, between an English force under Sir Conyers Clifford and a rebel Irish force led by Aodh Rua Ó Dónaill.

In 1599, the city fell to the Rakhine forces led by the Portuguese mercenary Filipe de Brito e Nicote, who was made governor of the city.

They succeeded in their efforts in 1599 with the Synod of Diamper. The representatives of various parishes who attended the assembly were forced by Portuguese authorities to accept the Papal authority.

He then convened a Synod at Udayamperoor, south of Ernakulam, from 20 – 26 June 1599, known as the Synod of Diamper.

Some time after the Synod of Diamper, on 25 November 1599, a letter was send to Pope by Archdeacon, giving information about the Synod and its work.

Over the course of the 16th century the Portuguese padroado progressively extended its control over the community, culminating with the Synod of Diamper in 1599, which formally brought the Saint Thomas Christians into Latin Rite Catholicism and replaced traditional East Syrian liturgy with Latinized liturgy.

The event in 1653 broke the fifty four year old yoke of Roman supremacy imposed at the Udayamperur Synod of 1599.