Synthetic antibiotic chemotherapy as a science and development of antibacterials began in Germany with Paul Ehrlich in the late 1880s.

In the late 1880s, Carnegie Steel was the largest manufacturer of pig iron, steel rails, and coke in the world, with a capacity to produce approximately 2, 000 tons of pig metal per day.

In the late 1880s many of the Hazara tribes revolted against Abdur Rahman, the first ruler to bring the country of Afghanistan under a centralized Afghan government.

The political terms of " modern ", " progressive " or " new " Liberalism began to appear in the mid to late 1880s and became increasingly common to denote the tendency in the Liberal Party to favour an increased role for the state as more important than the classical liberal stress on self-help and freedom of choice.

By the 1860s, there were around 5, 000 residents, and the population grew to around 10, 000 by the late 1880s.

Ure's own operation at Deception Pass in the late 1880s consisted of Ure and his Native-American wife.

Esperanto was created in the late 1870s and early 1880s by Dr. Ludwig Lazarus Zamenhof, an ophthalmologist of mixed cultural heritage from Bialystok, then part of the Russian Empire.

However, late 1880s Boston star Mike " King " Kelly is odds-on the most likely model for Casey's baseball situations.

Opened during the 1880s and originally located at 11th Street and University Place, called the Hotel St. Stephan and then after 1902, called The Hotel Albert while under the ownership of William Ryder it served as a meeting place, restaurant and dwelling for several important artists and writers from the late 19th century well into the 20th century.

In the late 1880s, the American Herman Hollerith invented data storage on a medium that could then be read by a machine.

Fueled by news stories of mountain feuds, such as that in the 1880s between the Hatfields and McCoys, the hillbilly stereotype developed in the late 19th and early 20th centuries.

The ship designator and hull number system's roots extend back to the late 1880s, when ship type serial numbers were assigned to most of the new-construction warships of the emerging " Steel Navy ".

During the late 1880s, the strong influence of Spanish style is evident in Albéniz's music.

By the late 19th century ( 1880s ) the machine gun had become an effective battlefield weapon.

By the late 1880s, Davis began to encourage reconciliation, telling Southerners to be loyal to the Union.

A rust plague in the late 1880s killed off much of the plantation stocks in Sukabumi, before spreading to Central Java and parts of East Java.

Low non-military demand and government subsidies meant that the company specialized more and more in weapons: by the late 1880s the manufacture of armaments represented around 50 % of Krupp's total output.

Kerosene started replacing lard oil in the 1870s and the lighthouse service was finally converted by the late 1880s.

Karl Wittgenstein ( 1847 – 1913 ) became an industrial tycoon, and by the late 1880s was one of the richest men in Europe, with an effective monopoly on Austria's steel cartel.

mid 1880s until late 1890s: some tribes stay at war ( see 1896-1900, Presidency Coleman )

Throughout the late 1880s, Weber continued his study of law and history.

Perhaps on account of his prominent role in Wilhelm's upbringing, Bismarck believed that he could dominate the young Kaiser and showed little respect for his policies in the late 1880s.

In the late 1880s and early 1890s, Heaviside worked on the concept of electromagnetic mass.

The National Republican Association-Colorado Party ( Asociación Nacional Republicana-Partido Colorado ) dominated Paraguayan political life from the late 1880s until Liberals overthrew it in 1904.

As with many California cities, the history of its development can be traced back to the completion of a cross-country railroad in the late 1880s.

But things were worked out in the family and late in August he wrote Miss McCrady an explanatory letter in which he told her that matters at home had been in an unsettled condition after Papa's death and he had not known whether he would stay at home with Mama, accept the Northwestern job, or return to Harvard.

Just before game time, Robinson's pretty wife, Connie informed him that an addition to the family can be expected late next summer.

Unfortunately, the family was left unprovided for after a conflict between the local Nizaris and Imani Khan Farahani, who had been married to one of the late Imam's daughters Shah Bibi and who had been in charge of the Imam's land holdings.

Pallas stated to the emperor that as Lucius was the grandson to Claudius's late brother Germanicus, by marrying Agrippina, Claudius would ally the two branches of the Claudian house and imperial family.

Ahenobarbus was the name of a plebeian family of the Domitia gens in the late Republic and early Principate of ancient Rome.

In late February or early March 1902 he fathered a child with Marie Scheuchl, a servant girl in the Berg family household.

A fire in the late 17th century was followed by some repairs, but in 1725 the family purchased 17th century Aberdour House, on the west side of the burn and in Wester Aberdour, and the medieval Castle was allowed to fall into relative decay.

In late October 1938, when he was living in a rented room in the home of a Jewish family in Frankfurt, he was arrested by the Gestapo and deported to Poland.

The last major structural additions were made in the late 19th and early 20th centuries, including the East front which contains the well-known balcony on which the royal family traditionally congregates to greet crowds outside.

These birds are generally solitary or found in pairs early in the year, but family groups are common in the late summer and winter roosts may have two dozen or more birds in a single covey.

After becoming New York's de facto Red Light District in the 1960s and 1970s ( as can be seen in the films Taxi Driver and Midnight Cowboy ), since the late 1980s Times Square has emerged as a family tourist center, in effect being Disneyfied following the company's purchase and renovation of the New Amsterdam Theatre on 42nd Street in 1993.

The Senate met in St Sophia and offered the crown to Theodore Lascaris, who had married into the Angelid family, but it was too late.

The family remained at the centre of civic and religious life throughout the late Middle Ages.

A late 13th century genealogy of her family listed her as 13 years old in the spring of 1137.

Most of the manuscripts were, however, late Greek manuscripts of the Byzantine textual family and Erasmus used the oldest manuscript the least because " he was afraid of its supposedly erratic text.

Genealogy received a boost in the late 1970s with the television broadcast of Roots: The Saga of an American Family, Alex Haley's account of his family line.

A different approach was taken in Flanders starting in the late 16th century, notably by the Ruckers family.

The family will eventually split up in late fall or early winter.

The property used to be owned by Thomas C. MacCready in the late 19th century, and after three generations of family, Douglas, Lynn, and Willis MacCready donated the land to Michigan State University in 2001.

He was raised as a Christian Scientist and spent his early childhood in Leland, Miss., moving with his family to Hyattsville, Maryland, near Washington, D. C., in the late 1940s.

Later that year, he and his family fled the Franco-Prussian War, moving to Cherbourg and Gréville, and did not return to Barbizon until late in 1871.

In the late 4th century AD, the famous Kuchanese monk Kumārajīva, born to an Indian noble family, studied Dīrghāgama and Madhyāgama in Kashmir under Bandhudatta.

With remaining revenues, St-Laurent oversaw the expansion of Canada's social programs, including establishment of the Canada Council to support the arts, and the gradual expansion of social welfare programs such as family allowances, old age pensions, government funding of university and post-secondary education and an early form of Medicare termed Hospital Insurance at the time, that lay the groundwork for Tommy Douglas ' healthcare system in Saskatchewan and Pearson's nationwide universal healthcare in the late 1960s.

* Margrave is a late addition to the family of Human colonies.

Brando's notoriety, his troubled family life, and his obesity attracted more attention than his late acting career.