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BCG and vaccine
One example of an abscess is a BCG-oma, which is caused because of incorrect administration of the BCG vaccine.
Bacillus Calmette – Guérin ( or Bacille Calmette – Guérin, BCG ) is a vaccine against tuberculosis that is prepared from a strain of the attenuated ( weakened ) live bovine tuberculosis bacillus, Mycobacterium bovis, that has lost its virulence in humans by being specially subcultured ( 230 passages ) in an artificial medium for 13 years, and also prepared from Mycobacterium tuberculosis.
At best, the BCG vaccine is 80 % effective in preventing tuberculosis for a duration of 15 years ; however, its protective effect appears to vary according to geography.
The BCG vaccine was first used in humans in 1921.
# Exposure to ultraviolet light: Concentration of ultraviolet light ( particularly UVB light ) from the Sun may have some effect on efficacy of the BCG vaccine.
UVB has been demonstrated to reduce efficacy of BCG vaccine in laboratory guinea pigs.
* Cancer immunotherapy / cancer vaccine: A number of cancer vaccines use BCG as an adjuvant to provide an initial stimulation of the patients ' immune systems.
BCG vaccine should be given intradermally.
Statens Serum Institut in Denmark markets BCG vaccine prepared using Danish strain 1331.
Japan BCG Laboratory markets its vaccine, based on the Tokyo 172 substrain of Pasteur BCG, in 50 countries worldwide.
Sanofi-Pasteur's BCG vaccine products, made with the Glaxo 1077 strain, were recalled in July 2012 due to noncompliance in the manufacturing process.
WHO established an epidemiological information service via telex in 1947, and by 1950 a mass tuberculosis inoculation drive ( using the BCG vaccine ) was under way.
In July 1921, at the Pasteur Institute in Lille, Albert Calmette and Camille Guérin discovered the first anti-tuberculosis vaccine, known as BCG (" Bacille de Calmette et Guérin ").
The health reform coincided with the development of a new vaccine and of new drugs ( e. g. BCG and penicillin ) that helped to treat a previously untreatable group of medical conditions.
* Albert Calmette and Camille Guérin discovered how to culture the tuberculosis bacillus, Mycobacterium tuberculosis ( so called BCG or Bacillus Calmette-Guérin ) at Institut Pasteur de Lille and developed in 1921 the first effective antituberculosis vaccine ;
Until 2005, the test was used in the United Kingdom to determine if the BCG vaccine was needed ; the Mantoux test is now used instead.
Most patient are aged less than 5 years, but the incidence is rare for children having BCG vaccine.
This vaccine produces higher levels of long-lasting cellular immunity when used together with the old TB vaccine called BCG.
He discovered the Bacillus Calmette-Guérin, an attenuated form of Mycobacterium used in the BCG vaccine against tuberculosis.
Finally, in 1921, they used BCG to successfully vaccine newborn infants in the Charité in Paris.

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