Most mutations in CMT affect the myelin sheath, but some affect the axon.

Most, but not all, mutations in regulatory genes result in non-viable zygotes.

Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer.

Most of these mutations destroy the ability of the protein to bind to its target DNA sequences, and thus prevents transcriptional activation of these genes.

Most of the short sequence repeats within protein-coding portions of the genome have a repeating unit of three nucleotides, since that length will not cause frame-shift mutations ( Sutherland 1995 ).

Most Tay – Sachs mutations probably do not directly affect protein functional elements ( e. g., the active site ).

Most ( 60 %) are homozygous for ATP7B mutations ( two abnormal copies ), and 30 % have only one abnormal copy.

Most patients who are homozygous for HFE mutations will not manifest clinically relevant haemochromatosis ( see Genetics below ).

Most of the mutations in this gene lead to the production of an abnormally short microsomal triglyceride transfer protein, which prevents the normal creation of beta-lipoproteins in the body.

' Most people had thought that they were " tank-bred mutations ", " ugly creatures who excreted slimy, foul-smelling residue, and whose multiple mouths ground incessantly on garbage ", even though they enjoy devouring the flesh of these beasts ( marinated slig medallions in rich Caladan wine sauces are considered a prime delicacy ).

Most loss of function mutations are selected against.

Most of those mutations are missense mutations and inherited mostly in a dominant manner.

Most WFS1 mutations replace one of the protein building blocks ( amino acids ) used to make wolframin with an incorrect amino acid.

Most cases do not have mutations in any of these genes.

Most proteins can withstand one or two point mutations before their functioning changes.

Most retrotransposons are very old and through accumulated mutations, are no longer able to retrotranspose.

Most mutations are disasters, but perhaps some inspired few are not.

Most of the known causes of congenital heart disease are sporadic genetic changes, either focal mutations or deletion or addition of segments of DNA.

Most cases appear to be due to three mutations.

Most of the stock of ' Bramley's Seedling ' commercially available is slightly different in its growth habit and other characteristics from the original tree, probably because of a chance mutation ( or mutations ) that occurred unnoticed over the years.

Most commonly, patients have mutations in the PEX1, PEX2, PEX3, PEX5, PEX6, PEX10, PEX12, PEX13, PEX14, PEX16, PEX19, and PEX26 genes.

Most of these mutations either substitute one amino acid ( a building block of proteins ) for another amino acid in the CFTR protein or delete a small amount of DNA in the CFTR gene.

Most mutations are detrimental.

Most frogs can be classified as either prolonged or explosive breeders.

Most aquatic species have a totally submerged juvenile phase, and flowers are either floating or emergent.

Most notably, Ajax is not wounded in any of the battles described in the Iliad, and he is the only principal character on either side who does not receive personal assistance from any of the gods who take part in the battles.

Most of the slaves liberated by Abu Bakr were either women or old and frail men.

Most Amiga models can be upgraded either by direct CPU replacement or through expansion boards.

Most aircraft hijackers intend to use the passengers as hostages, either for monetary ransom or for some political or administrative concession by authorities.

Most modern assassinations have been committed either during a public performance or during transport, both because of weaker security and security lapses, such as with U. S. President John F. Kennedy and former Pakistani Prime Minister Benazir Bhutto, or as part of coups d ' état where security is either overwhelmed or completely removed, such as with Patrice Lumumba and likely Salvador Allende.

Most scholars hold that the Hebrew text underlying the Septuagint version is older than the Masoretic text and that either the Masoretic evolved either from this vorlage or from a closely related version.

" Rabbi Joseph Telushkin wrote, " Most of the great women in the Bible either are married to a great man or related to one.

Most traditional pharmaceutical drugs are relatively small molecules that bind to particular molecular targets and either activate or deactivate biological processes.

Most of these early compositions are either scored for piano solo or include a piano.

Most accounts incorrectly attribute this story to Herodotus ; actually, the story first appears in Plutarch's On the Glory of Athens in the 1st century AD, who quotes from Heracleides of Pontus's lost work, giving the runner's name as either Thersipus of Erchius or Eucles.

Most games begin with a specific layout of cards, called a tableau, and the object is then either to construct a more elaborate final layout, or to clear the tableau and / or the draw pile or stock by moving all cards to one or more " discard " or " foundation " piles.

Most canals have a limit on height imposed either by bridges or by tunnels.

Most organized rides, for example Cyclosportives, Challenge Rides or reliability trials, and hill climbs include registration requirements and will provide information either through the mail or online concerning start times and other requirements.

Most quantitative calculations in modern quantum chemistry use either valence bond or molecular orbital theory as a starting point, although a third approach, Density Functional Theory, has become increasingly popular in recent years.

Most modern CVD processes are either LPCVD or UHVCVD.

Most modern semiconductor volatile memory is either Static RAM ( see SRAM ) or dynamic RAM ( see DRAM ).

writes: " Most famous horses are said to come either from Sindhu or Kamboja ; of the latter ( i. e the Kamboja ), the Indian epic Mahabharata speaks among the finest horsemen ".

Most divers have pre-dive and post-dive rituals that help them either maintain or regain focus.

Most of them can be classified as either key-value stores or document-oriented databases.

Most drawing media are either dry ( e. g. graphite, charcoal, pastels, Conté, silverpoint ), or use a fluid solvent or carrier ( marker, pen and ink ).

Most known fungal viruses have either double stranded DNA or RNA genomes.