* IARC TP53 Somatic Mutations database maintained at IARC, Lyon, by Magali Olivier

Koolhaas's next landmark publications were a product of his position as professor at Harvard University, in the design school's " Project on the City "; firstly the 720-page Mutations, followed by The Harvard Design School Guide to Shopping ( 2002 ) and The Great Leap Forward ( 2002 ).

Suddenly, evolutionary theorists could answer the charge that spontaneous random mutations should result overwhelmingly in deleterious changes to a fragile, monolithic genome: Mutations in homeobox regulation could safely — yet dramatically — alter morphology at a high level, without damaging coding for specific organs or tissues.

Mutations usually sound at pitches in the harmonic series of the fundamental and, except where they are derived from unit ranks, are always tuned pure.

Mutations in some homeotic genes can often be lethal and the cycle of life will end at embryogenesis.

COUM's earliest public events were impromptu musical gigs performed at various pubs around Hull ; titles for these events included Thee Fabulous Mutations, Space Between the Violins, Dead Violins and Degradation and Clockwork Hot Spoiled Acid Test.

* Beck's " High Five ( Rock the Catskills )" on the album Odelay ( 1996 ), starting at 2: 10 and finishing at 2: 30 ; and on " Tropicalia " from the album Mutations ( 1998 ) played by Smokey Hormel

Mutations in the Notch 3 gene ( on the short arm of chromosome 19 ) cause an abnormal accumulation of Notch 3 at the cytoplasmic membrane of vascular smooth-muscle cells both in cerebral and extracerebral vessels, seen as granular osmiophilic deposits on electron microscopy.

Mutations in the fukutin gene, located at human chromosome 9q31, are the cause of FCMD.

He wrote seven songs with the band-" Ill in the Head " and " Forward to Death ", both of which appear on the band's debut album Fresh Fruit for Rotting Vegetables ; " Short Songs ", " Gaslight ", and " Straight A's ", which appear on the live album Live at the Deaf Club ; " Mutations of Today ", which appears on The 1978 Demos ; and " Religious Vomit ", which appears on the EP In God We Trust, Inc ..

Mutations in these photo receptors and their signal transduction components lead to seedling development that is at odds with light conditions, for example seedlings that show photomorphogenesis when grown in the dark.

Mutations in nsP2 that produce noncytopathic viruses or a temperature sensitive phenotypes cluster at the P2 / P3 interface region.

Mutations in tafazzin that cause Barth syndrome span many different categories: missense, nonsense, deletion, frameshift, splicing ( see Human Tafazzin ( TAZ ) Gene Mutation & Variation Database ).

Mutations in the HLCS gene reduce the activity of holocarboxylase synthetase, preventing cells from using biotin effectively and disrupting many cellular functions.

* Mutations in the TDP-43 gene ( known as TARBP or TAR DNA-binding protein ) are an exceptionally rare cause of FTLD, despite this protein being present in the pathological inclusions of many cases ( FTLD-TDP43 ).

Mutations in the androgen receptor gene can cause problems with any of the steps involved in androgenization, from the synthesis of the androgen receptor protein itself, through the transcriptional ability of the dimerized, androgen-AR complex.

Mutations in elements of the Notch signaling pathway affect the earliest intestinal cell fate decisions during zebrafish development.

Mutations in the upstream components of the ERK5 pathway ( the CCM complex ) are thought to underlie cerebral cavernous malformations in humans.

Mutations in the pathway produced bizarrely-shaped fruit fly embryos.

Mutations in the pathway in adults promote degenerative disease and cancer.

Mutations in JAG1 disrupt the signaling pathway, causing errors in development, especially of the heart, bile ducts in the liver, spinal column, eyes, blood vessels and certain facial features.

Mutations in the gene for the prion protein can cause a misfolding of the dominantly alpha helical regions into beta pleated sheets.

One deck represents random Alpha Mutations, which can be drawn to gain temporary powers, and the other contains various Omega Tech, powerful technological devices that could possibly backfire on those that use them.

Mutations in the gene HR can lead to complete hair loss, though this is not typical in humans.

Mutations can have an impact on the phenotype of an organism, especially if they occur within the protein coding sequence of a gene.

Mutations can involve large sections of DNA becoming duplicated, usually through genetic recombination.

Mutations can involve large sections of DNA becoming duplicated, usually through genetic recombination.

Mutations in such microRNAs ( known as oncomirs ) can lead to activation of oncogenes.

Mutations in genes can cause also affect skin colour through oculocutaneous albinism ( OCA ) – a lack of pigment in the eyes, skin and sometimes hair that occurs occasionally in a very small fraction of the population.

* Mutations in the OFD1 gene can also cause several other disorders with features that overlap with those of oral-facial-digital syndrome.

Mutations can be detected in 90 %.

Mutations of mitochondrial DNA can lead to a number of illnesses including exercise intolerance and Kearns-Sayre syndrome ( KSS ), which causes a person to lose full function of heart, eye, and muscle movements.

Mutations in these proteins can result in altered functionality of sub-complex assembly, copper transport, or translational regulation.

Mutations of the FOXP3 gene can prevent regulatory T cell development, causing the fatal autoimmune disease IPEX.

Mutations can be caused by copying errors in the genetic material during cell division and by exposure to radiation, chemicals, or viruses, or can occur deliberately under cellular control during the processes such as meiosis or hypermutation.

Mutations and natural selection can only " remove preexisting information.

Mutations can involve large sections of DNA becoming duplicated, usually through genetic recombination.

Mutations are likely to be rare and most mutations are neutral or deleterious, but in some instances the new alleles can be favored by natural selection.

Mutations in a number of different genes as well as RAS itself can have this effect.

Mutations in these areas can lead to non-functional proteins that can polymerise and accumulate in the liver ( infantile hepatic cirrhosis ).

Mutations affecting repressor are said to be recessive to wild type ( and that wild type is dominant ), and this is explained by the fact that repressor is a small protein which can diffuse in the cell.

Mutations of the gene for this enzyme can cause unusual forms of diabetes or hypoglycemia.

* SGSH Mutations can cause Sanfilippo syndrome