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Once in the nucleus, Cyclin B1 / CDK1 phosphorylates many targets in preparation for mitosis, including Histone H1, nuclear lamins, centrosomal proteins, and Microtubule Associated Proteins ( MAPs ).
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Once and nucleus
Once the process succeeds, a very large amount of energy is released and the combined nucleus assumes a lower energy level.
Once the complex is in the nucleus, RanGTP binds to Importin-β and displaces it from the complex.
Once transported into the nucleus Ran GTP would bind to the importin and cause it to release the cargo.
Once the image is spatially encoded by the centre surround structures, the signal is sent out the optical nerve ( via the axons of the ganglion cells ) through the optic chiasm to the LGN ( lateral geniculate nucleus ).
This time two atoms of flerovium were produced, decaying by 10. 29 MeV alpha-emission with a half-life of 5. 5 s. They were assigned as < sup > 287 </ sup > Fl .< ref name =" 99Og02 "> Once again, this activity has not been seen again and it is unclear what nucleus was produced.
Once EBV enters the cell, the viral capsid dissolves and the viral genome is transported to the cell nucleus.
Once leptin has bound to the Ob-Rb receptor, it activates the stat3, which is phosphorylated and travels to the nucleus to, it is presumed, effect changes in gene expression.
Once their energy has decreased to thermal level, they diffuse randomly away from the source and are ultimately absorbed by a nucleus.
: Once inside the skull, the visceral sensory fibers enter the lateral medulla between the olive and the inferior cerebellar peduncle and descend in the tractus solitarius to synapse in the caudal nucleus solitarius.
Once in the nucleus, the steroid-receptor ligand complex binds to specific DNA sequences and induces transcription of its target genes.
Once inside the nucleus, VIP2 may target the T-DNA to areas of chromatin that are being actively transcribed, so that the T-DNA can integrate into the host genome.
Once this mucus shell evaporates the remaining viron is called a droplet nucleus or quanta.
Once in the nucleus the large T antigen binds three viral DNA sites, I, II, and III.
Once in the cytoplasm, the intact virus is translocated to the nucleus prior to uncoating.
Once assembled capsids are available, replication shifts from synthesizing duplex DNA to displacement of progeny single strands, which are typically negative-sense and are packaged in a 3 '- to-5 ' direction into preformed particles within the nucleus.
Once in the cytosol, Morpholinos freely diffuse between the cytosol and nucleus, as demonstrated by the nuclear splice-modifying activity of Morpholinos observed after microinjection into the cytosol of cells.
Once the virus newly infects a cell, the lipid membrane is shed and the virion travels to the nucleus.
Once the activated transcription factors reaches the nucleus it binds to consensus DNA-recognition motif called gamma activated sites ( GAS ) in the promoter region of cytokine inducible genes and activates transcription of these genes.
Once inside the nucleus the active STAT dimer binds to cytokine inducible promoter regions of genes containing gamma activated site ( GAS ) motif and activate transcription of these genes.
Once and /
Once this occurs, corrosive elements act as an electrolyte and the zinc / iron combination as electrodes.
Once registered, the new PAUSE account has a directory in the CPAN under authors / id /( first letter )/( first two letters )/( author ID ).
Once in place, democratic institutions — even partial ones — reduce the likelihood of armed conflict and all but eliminate the risk that it will lead to geno / politicide.
Once the actors are onboard the Protector, they finally realize the truth, but Sarris prevents them from leaving, so they assume their television roles in order to save the Thermians, who have very little concept of deception, or the art of acting / theater.
Once the fund is able to sell the side pocket assets, the fund will generally redeem the side pocket interests / shares and pay investors the proceeds.
Once the concept of broadband Internet access came to be associated with data rates incoming to the customer at 256 kbit / s or more, and alternatives like ADSL grew in popularity, the consumer market for BRI did not develop.
Once a call is set up, there is a simple 64 kbit / s synchronous bidirectional data channel ( actually implemented as two simplex channels, one in each direction ) between the end parties, lasting until the call is terminated.
Once deglaciation was complete, uplift slowed to about 2. 5 cm / year, and decreased exponentially after that.
On Chomsky specifically, he writes that " imaginary problems were created by the whole series of dichotomies that Chomsky introduced, or took over unproblematized: not only syntax / semantics but also grammar / lexis, language / thought, competence / performance ... Once these dichotomies had been set up, the problem arose of locating and maintaining the boundaries between them linguistics "
Once it was determined that VMware was not a possibility, it hired a group of Russian software developers to write a host-based hypervisor that would officially support OS / 2.
Once a child completes his / her primary education, they must then move up to secondary school.
Once this was understood, the various reign lengths and cross-synchronisms for these kings was worked out, and the sum of reigns for both kingdoms produced 931 / 930 BC for the division of the kingdom when working backwards from the Battle of Qarqar in 853 BC.
Once again, the problem of lifting a vector rotation to a spinor rotation is two-valued: the expression ( 1 ) with ( 180 ° + θ / 2 ) in place of θ / 2 will produce the same vector rotation, but the negative of the spinor rotation.
Once that relatively low data limit is reached the customer has to recharge the service using a prepaid card at a rate of approximately 10 u $ s / GB.
Once these targets had been identified, they would have been subject to what in essence would have been combined tactical nuclear weapons attacks by the V-Force until they had all been identified and / or destroyed.
Wim Wenders Photo Exhibition, in conjunction with the publication, Once, Munich: Schirmer / Mosel ( 2001 ), touring exhibition: Palazzo delle Esposizioni, Rome ( 1993 ); Villa delle Rose, Bologna ( 1994 ); FNAC, Paris ( 1994 ); Parco, Tokyo ( 1994 ); FNAC, Berlin ( 1995 ); Villa Rufolo, Ravello ( 1995 )
Once 4 / 5 of the Rumours-era band was reunited, the members decided a reunion was possible.
* Once More Frank 7 / 12 / 76
Once outside the formal schooling environment SEALs entering a new Team at the beginning of an operational rotation can expect 18 months of Professional Development / Schools ( PRODEV ) and Troop unit level training ( ULT ) before each 6-month deployment.
Once the results from data mining ( potential prospect / customer and channel / offer ) are determined, this " sophisticated application " can either automatically send an e-mail or a regular mail.
Once and phosphorylates
Once activated, PI 3-kinase phosphorylates PIP < sub > 2 </ sub > to form PIP < sub > 3 </ sub >.
Once and many
Once, then -- for how many years or how few does not matter -- my world was bound round by fences, when I was too small to reach the apple tree bough, to twist my knee over it and pull myself up.
Once many years ago I sat at dinner next to Arthur Train, and the subject of The Nation came up.
Once many significant phrases are found in theory or in recurrent practice to provide for prosodic necessity, they are not to be defended for their semantic properties in isolated contexts.
Once there, influences as various as drama teacher Wilford Leach, the Maysles brothers, Michelangelo Antonioni, Jean-Luc Godard, Andy Warhol and Alfred Hitchcock impressed upon De Palma the many styles and themes that would shape his own cinema in the coming decades.
Once the 1906 season got underway, many programs began experimenting with the forward pass.
Once widely practised by many miners across the moor, by the early 1900s only a few tinners remained, and mining had almost completely ceased twenty years later.
Once there they heard a constitutional speech by Brutus not unlike many speeches and documents of western civilization subsequently.
Once unhealthy because of its many marshes, the Maremma was drained during the fascist regime and re-populated with people coming from other Italian regions, notably from Veneto.
Once inside the cell, they bind to and activate estrogen receptors which in turn modulate the expression of many genes.
Once the wafers are prepared, many process steps are necessary to produce the desired semiconductor integrated circuit.
Once exiled, Thucydides took permanent residence in the estate and, given his ample income from the gold mines, he was able to dedicate himself to full-time history writing and research, including many fact-finding trips.
Once in files on a host machine, the software can be executed on one of many emulators, on virtually any platform available today.
Once the convention came to order, Arkansas Senator James K. Jones, chair of the Committee on Resolutions, read the proposed platform to cheers by many delegates ; the reading of the pro-gold minority report attracted less applause.
Once Upon a Time in the West emerged as a long, violent, dreamlike meditation upon the mythology of the American Old West, with many stylistic references to iconic western films.
Once they obtained their toll, the O ' Flaherty ships would disappear into one of the many bays in the area.
Once these sequences have been amplified, they are resolved either through gel electrophoresis or capillary electrophoresis, which will allow the analyst to determine how many repeats of the microsatellites sequence in question there are.
Once fishermen and biologists caught on to rising striped bass populations, many state natural resources departments started stocking striped bass in local lakes.
Once in India, hippies went to many different destinations, but gathered in large numbers on the beaches of Goa and Kovalam in Trivandrum ( Kerala ), or crossed the border into Nepal to spend months in Kathmandu.
Once California was established as a prosperous state many thousands more emigrated each year for the opportunities there.
Once the facial paralysis sets in, many people may mistake it as a symptom of a stroke.
Once it reaches three months, the cheese produces its notorious smell because the bacterium used to ferment Limburger cheese and many other smear-ripened cheeses is Brevibacterium linens, the same one found on human skin that is partially responsible for body odor and particularly foot odor.
Once thought to be a useless byproduct of insulin production, it helps to ameliorate and reverse many symptoms of diabetes.
Once Kip is well, he, Peewee, and the Mother Thing travel to a planet in the Lesser Magellanic Cloud, to face an intergalactic tribunal composed of many species which have banded together, which decides whether new races pose a danger.
Once, a wealthy area home to many beautiful mansions owned by various " big wigs ", the area is now a more affordable neighborhood, also housing the OKT, Lincoln Plaza, and Park Avenue residential housing communities.
Once a skateboarder masters the kickflip, many variations are possible:
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