In the Bextra case, the government also charged Pfizer with illegally marketing another antipsychotic, Geodon.

Phenytoin sodium has been marketed as Phenytek by Mylan Laboratories, previously Bertek Pharmaceuticals, and Dilantin ; Australia also Dilantin Kapseals and Dilantin Infatabs in the USA, Eptoin by Abbott Group in India and as Epanutin in the UK and Israel, by Parke-Davis, now part of Pfizer.

Pfizer also paid the U. S. government $ 1. 3 billion in criminal fines related to the " off-label " marketing of Bextra, the largest penalty ever rendered for any crime.

Pfizer also established an animal health division in 1959 with an farm and research facility in Terre Haute, Indiana.

Pfizer also has a licensing deal in place with Aurobindo which grants the former access to a variety of oral solid generic products.

The pharmaceutical company Pfizer also has operations located there, which in recent years has caused much controversy due to layoffs.

Morris Plains is also a major base of operations for Pfizer, previously the headquarters for Warner-Lambert.

Pfizer also sponsors the Health and Medical Science Academy at Morristown High School and has an annual 5k race around Morris Plains.

But it is also the seat of several large companies: Timken ( European seat ), Liebherr ( French seat ), Leitz ( French seat ), Capsugel France ( A division of Pfizer ) ...

It is marketed in the U. S. A. by Pfizer and globally by Sanofi under the trade name Flagyl, and is also sold under other brand names.

In 1994, Pfizer scientists discovered that sildenafil, which also inhibits the PDE5 enzyme, caused penile erection in men participating in a clinical study of a heart medicine.

Depo-subQ Provera 104, also manufactured by Pfizer, is a variation of the original Depo Shot that is instead a 104 mg subcutaneous injection.

Reuben was also a former paid spokesperson for Pfizer.

In late 2007, Pfizer released another U. S. television ad for Celebrex, which also discussed celecoxib's adverse effects in comparison with those of other anti-inflammatory drugs.

Valdecoxib was also used off-label for controlling acute pain and various types of surgical pain, though Pfizer was penalized for promoting such uses in US.

On April 7, 2005, Pfizer withdrew Bextra from the U. S. market on recommendation by the FDA, citing an increased risk of heart attack and stroke and also the risk of a serious, sometimes fatal, skin reaction.

He is also a director of J. P. Morgan Chase & Co., Prudential Financial Inc., Rockwell International Corporation, Visteon Corporation and Pfizer.

Grassley's letter also suggested that Pfizer resisted adding the blindness warning to Viagra's label.

The pharmaceutical company Pfizer is also a major employer.

In the Bextra case, the government also charged Pfizer with illegally marketing another antipsychotic, Geodon ; Pfizer settled that part of the claim for $ 301 million, without admitting any wrongdoing.

Pharmaceutical companies such as Pfizer and Oral-B have also based themselves in the town.

The area is home to the United States Coast Guard Academy in New London, a United States Navy base in Groton ( also home to Electric Boat where the first U. S. nuclear submarine, the USS Nautilus ( SSN-571 ), was launched, on January 21, 1954 ), a Pfizer research facility, and the Mohegan Sun and Foxwoods casinos.

He also received $ 145, 814 in other compensation ( primarily tax payments made by Pfizer on behalf of employees ), and nearly $ 5. 5 million in long-term incentive payouts.

The Pfizer drug company acquired the prototype from the university, along with rights to manufacture it.

In September 2009, Pfizer pleaded guilty to the illegal marketing of the arthritis drug Bextra for uses unapproved by the FDA, and agreed to a $ 2. 3 billion settlement, the largest health care fraud settlement at that time.

Pfizer lost nearly $ 1 billion invested developing the failed drug, and the market value of the company plummeted in the aftermath.

** Varenicline tartrate is a prescription drug marketed by Pfizer as Chantix in the U. S. ( under FDA approval ) and as Champix outside the U. S. Synthesized as an improvement upon cytisine, varenicline decreases the urge to smoke and reduces withdrawal symptoms .< ref > Two systematic reviews and meta-analyses supported by unrestricted funding from Pfizer, one in 2006 and one in 2009, found varenicline more effective than NRT or bupropion.

Key orphan drug developers including Synageva BioPharma Corp., Swedish Orphan Biovitrum, Shire plc, GlaxoSmithKline, Pfizer, Novartis, Genzyme, Lundbeck, Prosensa and BioMarin are leading the way in this growing industry.

Atorvastatin ( INN ) (), marketed by Pfizer as a calcium salt under the trade name Lipitor, is a member of the drug class known as statins, used for lowering blood cholesterol.

The drug was at the core of a major patent dispute that was resolved in Searle's favor ( later Pfizer ) in 2004.

Daniel L. Simmons of Brigham Young University, who discovered the COX-2 enzyme, is suing Pfizer to be credited with discovery of the technique in 1989 that eventually led to the drug, and for $ 1 billion USD.

The drug was originally researched as a treatment for cardiovascular diseases such as hypertension and angina, but focus quickly shifted to ED with the success of another PDE5 inhibitor, sildenafil ( Viagra ), which had been developed by Pfizer.

An example is the Taiwanese Mandarin word 威而剛 wēiérgāng ( weiergang ), which literally means " powerful and hard " and refers to Viagra, the drug for treating impotence in men, manufactured by Pfizer.

The CFPPC was particularly concerned with $ 15, 000 Marin received from the drug company Pfizer in 2007 which was simultaneously lobbying the Board of Pharmacy, a regulatory panel under her jurisdiction, and $ 13, 500 from Bristol-Myers Squibb in 2008 when it was likewise lobbying agencies she oversaw.

At the time, Pfizer was preparing to release its drug Chantix ( Varenicline ) into the Middle Eastern market.

This has been highly value generating: for example PA created a third-generation mobile phone business called UbiNetics which was sold in two tranches for a total of $ 133 million in 2005 ; and Meridica-a drug delivery system company-was valued at time of sale to Pfizer at $ 125 million in 2004.

In 2004, Pfizer " admitted that Parke-Davis aggressively marketed Neurontin by illicit means for unrelated conditions including bipolar disorder, pain, migraine headaches, and drug and alcohol withdrawal ", and consented to $ 430 million dollars in penalties although it claimed the violations originated in 1996, well before Pfizer's acquisition of Warner-Lambert.

Pfizer subsidiary Warner-Lambert illegally used scientific activities, including continuing medical education and research, to commercially promote gabapentin, so that within 5 years the drug was being widely used for the off-label treatment of pain and psychiatric conditions-conditions that had not been approved by FDA.

SSRI drugs, which have an important use as antidepressants, are considered to cause physical dependence, although it is considered mild compared to drugs like opioids and GABA modulators, but they engender a discontinuation syndrome, which was originally called " SSRI withdrawal " until a 1997 symposium sponsored by Pfizer and Eli Lilly ( the producers of several anti-depressants including Prozac and Effexor ) was held, with the drug representative attendees concluding that " discontinuation syndrome " sounded less threatening than " withdrawal "; however, " SSRI discontinuation syndrome " is a withdrawal syndrome upon discontinuation of SSRI / SNRI drugs, just as " heroin discontinuation syndrome " is a synonym for " heroin withdrawal ".

Dr. Reddy ’ s Para 4 application strategy for generic business received a severe setback when Reddy ’ s lost the patent challenge in the case of Pfizer ’ s drug Norvasc ( amlodipine maleate ), a drug indicated for the treatment of hypertension and angina.

Because of this, diphenoxylate is manufactured and marketed as a combination drug with atropine ( Lomotil, Pfizer ) as an abuse deterrent.

In 1996, Eisai received approval from the United States Food and Drug Administration ( USFDA ) for Aricept ( donepezil ), a drug discovered in the company's labs and co-marketed with Pfizer.

* FDA advisors have recommended that Pfizer be required to place a boxed warning on their non-steroidal anti-inflammatory drug Celebrex ( celecoxib ) for cardiovascular and gastrointestinal risks.

Pfizer described in an SEC filing that the drug could be used to treat epilepsy, post-herpetic neuralgia, diabetic peripheral neuropathy and fibromyalgia.

At Pfizer, Tweddell worked on drug development and medical relations.