They are known as 2 -, alpha -, or α-amino acids ( generic formula H < sub > 2 </ sub > NCHRCOOH in most cases < ref > Proline is an exception to this general formula.

Proline ( abbreviated as Pro or P ) is an α-amino acid, one of the twenty DNA-encoded amino acids.

Proline is biosynthetically derived from the amino acid-glutamate and its immediate precursor is the imino acid ( S )- 1-pyrroline-5-carboxylate ( P5C ).

Proline acts as a structural disruptor in the middle of regular secondary structure elements such as alpha helices and beta sheets ; however, proline is commonly found as the first residue of an alpha helix and also in the edge strands of beta sheets.

Proline is also commonly found in turns, which may account for the curious fact that proline is usually solvent-exposed, despite having a completely aliphatic side chain.

Proline is one of the two amino acids that do not follow along with the typical Ramachandran plot, along with glycine.

Proline hydroxylation is also a vital component of hypoxia response via hypoxia inducible factors.

Proline is never found in this site, possibly because it would break the helical structure adopted by this motif in metalloproteases.

Another less common mutation is a G --> C conversion resulting in one amino acid mutation in 696, where Proline substitutes normal Arginine.

Proline, a naturally occurring chiral compound, is readily and cheaply available.

Proline derivative 3d is prepared in a separate leg from a Grignard reaction with Grignard reagent 3c and proline ester 3b.

* Proline, an amino acid

: Proline residues may be hydroxylates at either of two atoms, as can lysine ( at one atom ).

The Atari 7800 came bundled with the Atari Proline Joystick a two button controller with a joystick for movement.

# Proline rich domain important for the apoptotic activity of p53: residues 64-92.

Proline and glycine are sometimes known as " helix breakers " because they disrupt the regularity of the α helical backbone conformation ; however, both have unusual conformational abilities and are commonly found in turns.

Proline and its derivatives are often used as asymmetric catalysts in organic reactions.

Proline, instead, produces an orange / yellow colour.

Proline destabilizes or breaks an α helix but can be present in longer helices, forming a bend.

image: L-proline-skeletal. png |- Proline ( Pro / P )

Proline enters a catalytic cycle by reacting with the aldehyde to form an enamine.

The mall hosts major anchor stores such as Westside ( spread across 20, 000 sq ft ) and Landmark ( 40, 000 sq ft ), and several local and international brands such as Nike, Adidas, Bata, Regal, Health & Glow, Vummidiars, Van Heusen, Proline, Allen Solly, Florshaim shoes, Louis Philippe, Titan, Levi ’ s, Casio, V. I. P.

" Sale of " lye relaxers " began in 1971 by companies such as Proline.

Also, there are the Fila, Proline & Raymond showrooms.

Proline residues are known to be structure-breaking residues, so these were directly grafted into the human sequence.

Bryn Mawr Drive is only two or three miles from the Spartan, and it took me less than five minutes to get there.

Actually, only two men know what the formula is, Blake and '' -- He stopped and looked at Thor's body.

In fact it has caused us to give serious thought to moving our residence south, because it is not easy for the most objective Southerner to sit calmly by when his host is telling a roomful of people that the only way to deal with Southerners who oppose integration is to send in troops and shoot the bastards down.

This is the only case in modern history of a people of Britannic origin submitting without continued struggle to what they view as foreign domination.

Recognizing that the Rule of Law is `` a dynamic concept which should be employed not only to safeguard the civil and political rights of the individual in a free society '', the Congress asserted that it also included the responsibility `` to establish social, economic, educational and cultural conditions under which his legitimate aspirations and dignity may be realized ''.

It is the gait of the human who must run to live: arms dangling, legs barely swinging over the ground, head hung down and only occasionally swinging up to see the target, a loose motion that is just short of stumbling and yet is wonderfully graceful.

They are huge areas which have been swept by winds for so many centuries that there is no soil left, but only deep bare ridges fifty or sixty yards apart with ravines between them thirty or forty feet deep and the only thing that moves is a scuttling layer of sand.

Others are confined to vast reservations, and not only does the Australian government justifiably not wish them to be viewed as exhibits in a zoo, but on their reservations they are extremely fugitive, shunning camps, coming together only for corroborees at which their strange culture comes to its highest pitch -- which is very low indeed.

`` Now that Bruno Walter is virtually in retirement and my dear friend Dimitri Mitropoulos is no longer with us, I am probably the only one -- with the possible exception of Leonard Bernstein -- who has this special affinity for and champions the works of Bruckner and Mahler ''.

Thus, there is freshness not only in the individual movements of the dance but in the shape of their continuity as well.

The answers derived by these means may determine not only the temporal organization of the dance but also its spatial design, special slips designating the location on the stage where the movement is to be performed.

I think it is essential, however, to pinpoint here the difference between the two concepts of sovereignty that went to war in 1861 -- if only to see better how imperative is our need today to clarify completely our far worse confusion on this subject.

To my knowledge, Lincoln remains the only Head of State and Commander-in-Chief who, while fighting a fearful war whose issue was in doubt, proved man enough to say this publicly -- to give his foe the benefit of the fact that in all human truth there is some error, and in all our error, some truth.

It is all around us and our only chance now is to let it in.

Together with cysteine, methionine is one of two sulfur-containing proteinogenic amino acids.

Glutamic acid ( abbreviated as Glu or E ) is one of the 20-22 proteinogenic amino acids, and its codons are GAA and GAG.

Amino acids containing a secondary amine group ( the only proteinogenic amino acid of this type is proline ) are sometimes named imino acids, though this usage is disputed by some.

The four constituents differ only in which of four proteinogenic amino acids is used in biosynthesis: