Significant enclaves of Karelians exist in the Tver oblast of Russia, resettled after Russia's defeat in 1617 against Sweden — in order to escape the peril of forced conversion to Lutheranism in Swedish Karelia and because the Russians promised tax deductions the Orthodox Karelians mass migrated there.

Significant failure of monsoon rains historically meant drought and famine while above-normal rains still cause flooding and landslides with losses in human lives, farmland and buildings.

Significant loan losses were reported in 1987 and while the bank participated actively in debt restructuring initiatives, it also committed itself to more conservative lending practices.

Significant poultry losses were experienced.

Significant instrument losses included two Steinway & Sons pianos and the blower and console units of the Schoenstein pipe organ.

Significant procurement and acquisition fraud, corruption, and other financial crimes which result in multi ‐ million dollars losses, thus depriving DoD of critically ‐ needed funds that would otherwise be utilized to finance vital national defense initiatives.

Significant items that contributed to the increased loss included an increase in operating losses to $ 583, 000 in the first quarter of fiscal 2007 as compared to $ 421, 000 in the first quarter of fiscal 2006.

Significant industries include IT, pharmaceuticals, biomedical engineering, biotechnology, electronics, traffic engineering, and renewable energy.

Significant amounts of energy and time were devoted to support and foster formal study of the balalaika, from which highly skilled ensemble groups such as the Osipov State Balalaika Orchestra emerged.

Significant problems with the metric of this form stem from the fact that all known warp drive spacetimes violate various energy conditions.

Significant fossil fuel energy resources exist in the Barents Sea region.

Significant recent efforts in fume hood and ventilation system design have focused on reducing the energy used to operate fume hoods and their supporting ventilation systems.

* Significant shift to investment in renewable energy

Significant articular incongruity typically occurs in young patients after high energy injuries ( Figure 2 ).

Significant amounts of energy are flushed out of buildings in the water, air and compost streams.

Significant scientific, interplanetary and industrial use did not occur until the 20th century, when rocketry was the enabling technology of the Space Age, including setting foot on the moon.

Significant alcohol intake produces changes in the brain's structure and chemistry, though some alterations occur with minimal use of alcohol over a short term period, such as tolerance and physical dependence.

Significant scientific, interplanetary and industrial use did not occur until the 20th century, when rocketry was the enabling technology of the Space Age, including setting foot on the moon.

Significant phase shifts may occur on paths wherein a reflection area of the path is subject to a large tidal range.

Significant weather forecasting problems that occur in the 0-to 12-hr range include severe weather in all seasons ( for example, tornadoes, thunderstorms, snow, and ice storms ) and hazards to aviation ( for example, clear air turbulence, icing, and downbursts ).

Significant rain events can occur in the spring and fall.

Significant growth in the area, aided its proximity to Abilene, began to occur in the late 1980s and by 1992 there were 1, 441 people living in Potosi.

Significant amounts of precipitation occur in all seasons in most areas.

Significant weight gain may also occur.

Significant variations in amplitude also occur.

Significant liver congestion may result in impaired liver function, and jaundice and even coagulopathy ( problems of decreased blood clotting ) may occur.

Significant aspiration can only occur if the protective reflexes are absent or severely diminished ( in neurological disease, coma, drug overdose, sedation or general anesthesia ).

Significant human impacts may nevertheless occur through anthropogenic climate warming.

Significant visual loss may occur and following a period of observation for spontaneous resolution, treatment with temporal peripapillary laser photocoagulation followed by vitrectomy and gas injection followed by face-down positioning is very effective in treating this condition.

Significant development did not occur until the post-war years, with rapid growth from the 1950s into the 1970s.

Significant riots began to occur on Chicago's West Side starting in 1965, and an especially damaging riot in 1968 ( after Martin Luther King's death ) prompted many white residents to leave.

Significant problems occur with airports where the grounds were or have become nesting areas for birds.

Significant populations occur in pockets in the waters off the Pribilof and Shumagin Islands, Shelikof Strait, Prince William Sound and at least as far south as lower Chatham Strait in the south-east, where a regular commercial fishery occurs annually.

Significant additional moisture contributions occur from fog drip off trees and rime deposition on trees, with many days during the year being spent amid orographic feeder clouds that cap its upper elevations.

Significant seismic damage may occur if the building response is ' in tune ' with components of the ground motion ( resonance ), which may be identified from the response spectrum.

Significant publications include a collection of texts, a grammar and a lexicon ( both published posthumously ), in addition to a theoretically significant article on Menomini phonological alternations.

Significant measures have been taken to liberalize the Tanzanian economy along market lines and encourage both foreign and domestic private investment.

Significant outcries surfaced both within Taiwan and abroad opposing the concept of Taiwan localization in the early years after President Chiang Ching-kuo's death, denouncing it as the " independent Taiwan movement " ( Chinese: 台獨運動 ).

Significant too is, where Jesus heals a man in a process that is slow and involves saliva ; Mark Goodacre suggests both these features make it a passage more likely to be omitted than added, implying Mark wrote first.

Significant elements of both of these styles ( the split eye, trophy heads, and staff-bearing profile figures, for example ) seem to have been derived from that of the earlier Pukara culture in the northern Titicaca Basin.

Significant opposition to the Iraq War occurred worldwide, both before and during the initial 2003 invasion of Iraq by the United States, United Kingdom, and smaller contingents from other nations, and throughout the subsequent occupation.

Significant quantities of nickel ( the primary target ) as well as copper and cobalt were subsequently extracted from this " ore " using both pyrometallurgical and hydrometallurgical methods.

Significant alterations were made in 1841 when both sides were widened, adding 45 cm to the width of the bridge.

As he told a Senate committee, " Significant cuts in the Defense Budget now would seriously weaken the U. S. position on international negotiations — in which U. S. military capabilities, in both real and symbolic terms, are an important factor.

Significant to the argument are the elegant experiments of William F. Towne, of the Kutztown University in Pennsylvania, such as this pdf file, in which hives are moved to " mirror image " terrain settings, and thus fooled into both dancing about the wrong location for a nectar source, and successfully recruiting foragers to that wrong location, but only when the sun is obscured by clouds, forcing them to rely on terrain-based navigation rather than " solar ephemeris " based navigation.

Significant results were reached in the following years both in scientific research and in the organization of teaching.

Significant factors contributing to its demise include: ( 1 ) the deaths of a substantial percentage of the Kalmyk population from disease and malnutrition, both during their travel and upon their arrival to remote exile settlements in Central Asia, south central Siberia and the Soviet Far East ; ( 2 ) the wide dispersal of the Kalmyk population ; ( 3 ) the duration of exile, which ended in 1957 ; ( 4 ) the stigma associated with being accused of treason, and ( 5 ) assimilation into the larger, more dominant culture.

Significant changes occurred in 1965, when the line was singled and both legs of the triangle at the eastern end of the line were closed.

Significant to the history of both approaches were the contributions made by Bernard Weiner in the 1970s.

Significant points on the journey include Crianlarich, an important Highland junction of both road and rail, and Tyndrum, the smallest place in Scotland to boast two railway stations.

Significant increases in both military and domestic expenditure, combined with tax cuts and a recession, all contributed to record budget deficits recorded during the Bush administration.

Significant events held here included the handing back of Perlis and Setul ( now Satun ) to Kedah by the Siamese in May 1897 ( both provinces were separated from Kedah since 1821 ) and a 90-day festival from June to September 1904 to celebrate the wedding of the five children of Sultan Abdul Hamid Halim Shah.

Significant Wraith technologies include culling beams and stunners, both of which primarily function to capture human prey.

Significant players it has produced have include Tom Richards, who played for both the British Isles and Australia, Sam Tucker, John Blake, John Pullin and Alan Morley.

Significant cities, both major and minor, are shown.

Significant excess mortality was found in both males and females.

Significant city council regeneration of private properties in the south of the area in 2005 has helped both the quality of housing and the respective house prices.