Significant results were produced by Croatian mathematician Danilo Blanuša, who discovered two snarks in the 1940s, now known as Blanuša snarks ; prior to Blanuša's discovery, the only known snark was the Petersen graph ( Weisstein ).

Significant heterogeneity of the molecule has been described, thus bioassays and immunoassays can give different results due to differing glycosylation, phosphorylation, sulfation, as well as degradation.

Interpretation Significant training is required to interpret the results of this assessment.

Significant results have been shown that extend the classical scalar Chernoff, Bernstein, and Hoeffding inequalities to the largest eigenvalues of finite sums of random Hermitian matrices.

The certified release of an Environmental Assessment results in either a Finding of No Significant Impact ( FONSI ) or an Environmental Impact Statement ( EIS ).

Significant differences from TCP were:

Significant amounts of energy and time were devoted to support and foster formal study of the balalaika, from which highly skilled ensemble groups such as the Osipov State Balalaika Orchestra emerged.

Significant wars were fought in Britain, where his general Agricola attempted to conquer Caledonia ( Scotland ), and in Dacia, where Domitian was unable to procure a decisive victory against king Decebalus.

" Significant amounts " of hexavalent chromium were found in the water of more than 40 homes in the area, some of which have now been fitted with state-monitored filters on their water supply.

Significant internal reforms were introduced during the later part of the 18th century, but the reform process was not allowed to run its course, as the Russian Empire, the Kingdom of Prussia and the Austrian Habsburg Monarchy through a series of invasions and partitions terminated the Commonwealth's independent existence in 1795.

Significant interpretations of his writings were produced by such sociological luminaries as Talcott Parsons and C. Wright Mills.

Significant contributions to oceanographic knowledge were made by the voyages of HMS Beagle in the 1830s, with Charles Darwin aboard ; HMS Challenger during the 1870s ; the USS Tuscarora ( 1873 – 76 ); and the German Gazelle ( 1874 – 76 ).

Significant amounts of the Soviet resources were allocated in aid to the other socialist states.

Significant events in the early development of rugby football were the production of the first set of written football laws at Rugby School in 1845, which was followed by the ' Cambridge Rules ' drawn up in 1848.

Significant amendments were made to the Constitution in 1991, and there have been a number of judicial interpretations made to take into account the fact that the Constitution covers a much smaller area than originally envisioned.

Significant were the contributions of Nicolas Jenson, Francesco Griffo, Aldus Manutius, and other printers of late fifteenth-century Europe.

Significant numbers of British Churchill and Matilda tanks along with US M3 Lee were shipped to the USSR after becoming obsolete on the African Front with the Churchills supplied by the arctic convoys seeing action around Leningrad while tanks shipped by the Persian route supplied the Caucasian Front.

Significant changes to the cathedral were made by the architect James Wyatt in 1790, including replacement of the original rood screen and demolition of the bell tower which stood about 320 feet ( 100 m ) north west of the main building.

Significant collections of Tiffany windows outside the United States are the 17 windows in the former Erskine and American United Church, now part of the Montreal Museum of Fine Arts in Montreal, Canada, and the two windows in the American Church in Paris, on the Quai d ' Orsay, which have been classified as National Monuments by the French government ; these were commissioned by Rodman Wanamaker in 1901 for the original American Church building on the right bank of the Seine.

Significant Huguenot settlements were in Dublin, Cork, Portarlington, Lisburn, Waterford and Youghal.

Significant early contributions to New Keynesian theory were compiled in 1991 by editors N. Gregory Mankiw and David Romer in New Keynesian Economics, volumes 1 and 2.

Significant events of the postwar era were the relocation of the university hospital from the city center to the Venusberg in 1949, the opening of the new university library in 1960 and the opening of a new building, the Juridicum, for the School of Law and Economics in 1967.

Significant evidence of this mining activity remains in the cave, including evidence of large amounts of saltpeter-bearing dirt that were removed, pick marks in the dirt, and an elaborate system of trails used by the miners.

* Significant portions of Fried Green Tomatoes were filmed in Newnan and Senoia.

Significant damage to an industrial plant with injuries, trapped people and destroyed homes were reported in Madison Parish near the Louisiana-Mississippi state line.

Significant gold mines in the nearby Santa Rosa Mountains were the National that produced in excess of 200, 000 ounces, and the Buckskin National that produced 24, 000 ounces of gold and 300, 000 ounces of silver over the period 1906 – 1941.

Significant portions of the 1961 film The Intruder ( Directed by Roger Corman and starring William Shatner ) were filmed in East Prairie.

Significant growth in the area, aided its proximity to Abilene, began to occur in the late 1980s and by 1992 there were 1, 441 people living in Potosi.

Significant changes in its management and language were brought in 1515 by Mahmoud Pasha Elekhani.

Significant cave art sites off the coast of western Europe such as the Grotto Cosquer can be reached only by diving, because the cave entrances are underwater, though the upper portions of the caves themselves are not flooded.

Significant fur trapping has continued in the region, but in general the east coast or East Main of James Bay was too easily accessed by French and independent traders from the south so early Hudson's Bay Company emphasis was quickly placed onto interior trapping grounds reached from the west coasts of James and Hudson Bays.

Significant percentages of CRs were eventually reached by the cortically-lesioned animals, but the CRs were low in amplitude and poorly timed.

The Forest Service reached a Finding of No Significant Impact ( FONSI ) and determined that boating would not have significant potential to damage the sensitive wilderness sections any more than any other user group.

Significant progress came following the work of Louis Pasteur and his advances in microbiology, when the British surgeon Joseph Lister began experimenting with using phenol during surgery to prevent infections.

Significant upgrades were temporarily put on hold following announcement of the new Angara launch vehicle.

Significant visual loss may occur and following a period of observation for spontaneous resolution, treatment with temporal peripapillary laser photocoagulation followed by vitrectomy and gas injection followed by face-down positioning is very effective in treating this condition.

Significant changes to the game's ending were made late in development following the September 11 attacks in New York, where the finale occurs.

Significant provisions of the treaty require that parties implement the following measures:

Significant intensification resumed on September 1, and by the following day, Betsy was a Category 3 hurricane.

Significant areas have become desertified following extensive slash-and-burn activity primarily from 1970 onward, as population pressures led indigenous peoples to seek agricultural production in increasingly unsustainable methods.

Significant buildings by Frey during this period include the following:

Significant structural work on Lithia Creek and the parks bridges in the years following this flood helped to prevent further disaster and turned Lithia Park it into the centerpiece of the town that it is today.

Significant sums were allegedly spent from the city budget for activities related to that club, which has virtually no following.

Significant ruins can be found at the following locations.

Significant events include the following.

Significant works ( with their titles in Norwegian ) include the following:

Significant numbers of Cretan Muslims were re-settled in other Ottoman controlled areas around the eastern Mediterranean by the Ottomans following the re-conquest of Crete by the Kingdom of Greece in 1898.