Since the tumors grow where there are nerves, they can also grow in areas that are visible, causing considerable social suffering for those affected.

Since Krukenberg tumors are secondary ( metastatic ), management might logically be driven by identifying and treating the primary cancer.

Since higher grade tumors are more likely to undergo metastasis ( invasion and spread to locoregional and distant sites ), they are treated more aggressively.

Since, by definition, benign bone tumors do not metastasize, all secondary bone tumors are metastatic lesions which have spread from other organs, most commonly carcinomas of the breast, lung, and prostate.

Since the gold nanoparticles are taken up by the tumors more than the nearby healthy tissue, the dose is selectively enhanced.

Since the adjacent structure is the pituitary gland, some common tumors causing compression are pituitary adenomas and craniopharyngiomas.

Since the center ’ s inception, faculty members have played a key role in the development of both Marquis, the first FDA-approved treatment for equine protozoal myelitis, and GastroGard, a treatment for gastric ulcers, as well as advances in laser surgery joint disease, and treatments for lameness, colic, tumors, tendon and ligament injury, and antibiotic therapy.

Since SNPs are a " quick and dirty " approach to detect genetic indicators of pathologies and lineages, arrays theoretically provide a facile method for diagnosis ; this was confirmed experimentally in the late 1990s in the successful SNP analysis of human tumors.

Since most tumors are supplied by the hepatic artery, arterial embolization interrupts their blood supply and postpones growth until replaced by neovascularity.

Since tumors overexpressing TSP-1 typically grow slower, exhibit less angiogenesis, and have fewer metastases, TSP1 is an attractive target for cancer treatment.

Since the middle of the sixth century BC, the rulers of Jin had steadily lost political powers to their nominally subordinate nobles and military commanders, a situation arising from the traditions of the Jin which forbade the enfeoffment of relatives of the ducal house.

Since many programmers were not generally familiar with this approach, early Mac programs suffered frequently from faults arising from this-faults that very often went undetected until long after shipment.

Since arising in the 19th century, the influence of Primitive Baptists has waned as " Missionary Baptists became the mainstream ".

Since then, and since the pure grain had gotten him divorced from every decent -- and even indecent -- group from Greenwich Village to the Embarcadero, he had become a sucker-rolling freight-jumper.

Since it is not far from Viareggio, he will visit Puccini's house, as he never fails to do, to pay his respects to the memory of the composer of La Boheme, which he considers one of Puccini's masterpieces.

Since the great flood of these dystopias has appeared only in the last twelve years, it seems fairly reasonable to assume that the chief impetus was the 1949 publication of Nineteen Eighty-Four, an assumption which is supported by the frequent echoes of such details as Room 101, along with education by conditioning from Brave New World, a book to which science-fiction writers may well have returned with new interest after reading the more powerful Orwell dystopia.

Those famous lines of the Greek Anthology with which a fading beauty dedicates her mirror at the shrine of a goddess reveal a wise attitude: `` Venus, take my votive glass, Since I am not what I was, What from this day I shall be, Venus, let me never see ''.

Since moving from a Chicago suburb to Southern California a few months ago, I've been introduced to a new game called Lanesmanship.

Since the Connally amendment has the effect of giving the same right to the other party to a dispute with the United States, it also prevents us from using the court effectively.

Since the provision of skywave service requires adequate freedom from interference, only class 1, stations are capable of rendering skywave service.

Says NRLDA's James Wright: `` Since 1958 carriers that move material from the yard to the job site have undergone more radical changes than any of the dealer's other equipment ''.

Since Af is ferromagnetic, we felt that any results obtained from the magnetically contaminated Af would be suspect.

Since there is a continual loss of micrometeoritic material in space because of the radiation effects, there must be a continual replenishment: otherwise, micrometeorites would have disappeared from interplanetary space.

Since a Skeletal Age rating can be made at any age during growth, from Elbow, Shoulder, Knee, or Foot as well as Hand, it seems to be the method of choice when one wishes to study most aspects of skeletal developmental progress during childhood.

Since the circulating thyroid hormones are the amino acids thyroxine and tri-iodothyronine ( cf. Section C ), it is clear that some mechanism must exist in the thyroid gland for their release from proteins before secretion.

Since emotional reactions in the higher vertebrates depend on individual experience and are aroused in man, in addition, by complex symbols, one would expect that the hypothalamus could be excited from the cortex.

Since the complex of singular lines is of order K and since there is no complex of invariant lines, it follows from the formula Af that the order of the involution is Af.

A final class of exceptional lines is identifiable from the following considerations: Since no two generators of Af can intersect, it follows that their image curves can have no free intersections.

Since that time the telegraph office has shifted in location from the railroad station at the Depot and shops at the Center back to the town clerk's office and drugstore at the Village.

Since none of these glimpses of poetizing without writing is intended to incorporate a signature into the epic matter, there is prima-facie evidence that Beowulf and the Homeric poems each derive from an oral tradition.

Since experience indicates that effluents from oxidation ponds do not create major problems at these BOD concentrations, the goal for the effluent quality of the accelerated treatment system was the same as from conventional oxidation ponds.

Since Biblical times, rosaries have been made from jobs-tears -- the seeds of an Asiatic grass.

Since Election Day, Vice President Richard Nixon had virtually retired -- by his own wish -- from public view.

Since the Protestant clergy for the most part wear gray or some variant from the wholly black suit, my Roman collar and black garb usually identify me in England as a Roman Catholic cleric.

Since the Catholic Church expresses such desire that the Sacred Scriptures be read, the following taken from the Holy Bible ( New Catholic Edition ) will prove a means of grace and a source of great spiritual blessing.

Since the hero, a sterling and upright fellow, is a rich Brown senior, while two Yalies are cast as virtual rapists, I suppose I should disqualify myself from sitting in judgment on `` Where The Boys Are '', but I shall do nothing of the sort.

Since a fall or blow might have caused it, a cold pack was usually first aid.

The number of neutrons, N, is known as the neutron number of the atom ; thus, A = Z + N. Since protons and neutrons have approximately the same mass ( and the mass of the electrons is negligible for many purposes ), and the mass defect is usually very small compared to the mass, the atomic mass of an atom is roughly equal to A.

Since the difference between the U. S. and International acre is only about a quarter of the size of an A4 sheet of paper ( 0. 016 square metres, 160 square centimetres or 24. 8 square inches ), it is usually not important which one is being discussed.

Since the development of cannon, the word " artillery " in practice has largely meant cannon ; in contemporary usage it usually refers to shell-firing guns, howitzers, mortars, and rockets.

Since he has never confirmed this, the story is usually considered apocryphal.

Since there is no heir to inherit Elimelech's land, levirate custom required a close relative ( usually the dead man's brother ) to marry the widow of the deceased in order to continue his family line ( Deuteronomy 25: 5 – 10 ).

Since 21 April 2008, the overnight bulletins, while produced by the BBC News Channel, have usually been broadcast from the studios of BBC World News.

Since commercial signage usually has limited physical space, signage is normally in French alone.

Since several elements are gases at commonly encountered temperatures, their densities are usually stated for their gaseous forms ; when liquefied or solidified, the gaseous elements have densities similar to those of the other elements.

Since the consolidation of newspaper comics by the first quarter of the 20th century, most cartoonists have used a group of assistants ( with usually one of them credited ).

Since the end of Capoeira prohibition, knifes or razors are unlikely to come around the roda, so usually this toque is played only in some presentations.

Since the shorts were produced during the rise of film noir in cinema, the change was usually represented as a stylized sequence: Clark Kent's silhouette is clearly seen behind a closed door's pebble glass window ( or a shadow thrown across a wall ) as he strips to his Superman costume.

Since large bodies such as planets generally carry no net charge, the electric field at a distance is usually zero.

Since it is no longer used as an antimalarial, tonic water today contains much less quinine, is usually sweetened, and is consequently much less bitter.

Since in organic chemistry non-carbons usually are considered to replace carbon atoms, they are called heteroatoms, meaning ' different from carbon and hydrogen ' ( rings of heteroatoms of the same element are homocyclic ).

Since prince-episcopal sees were so influential, competing candidates usually ran for them.

Since independence was granted in 1963 relations have been usually amicable, both being part of the Commonwealth of Nations, a successor to the empire which aims to promote mutual co-operation, democracy and other cultural values and ties with each member state.

Since the Early Modern period, the title of knight is purely honorific, usually bestowed by a monarch, as in the British honours system, often for non-military service to the country.

Since the end of World War II, the Christian Social People's Party ( CSV ) has usually been the dominant partner in governing coalitions.

Since computer screen images usually have full white somewhere in the picture, the backlight will usually be at full intensity, making this " feature " mostly a marketing gimmick.

Since combat engineers with mine-clearing equipment can clear a path through a minefield relatively quickly, mines are usually considered effective only if covered by fire.

Since the gall bladder is similar to a small balloon that stores and releases bile, it can usually be removed from the abdomen by suctioning out the bile and then removing the deflated gallbladder through the 1 cm incision at the patient's navel.

Since all events are sets, they are usually written as sets ( e. g.