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Since phospholipase enzymes play a significant part in the cascade leading to the inflammatory and pain response, their inhibition could lead to relief of problems from scorpion envenomation.
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Since and enzymes
Since enzymes are selective for their substrates and speed up only a few reactions from among many possibilities, the set of enzymes made in a cell determines which metabolic pathways occur in that cell.
Since enzyme reactions are very well known amplification processes, the signal is generated by enzymes which are linked to the detection reagents in fixed proportions to allow accurate quantification-thus the name " enzyme linked ".
Since the structure of a glycan may depend on the expression, activity and accessibility of the different biosynthetic enzymes, it is not possible to use recombinant DNA technology in order to produce large quantities of glycans for structural and functional studies as it is for proteins.
Since the secretory glands of Droseraceae contain proteases and possibly other degradative enzymes, it may be that the presence of oxygen-activating redox cofactors function as extracellular predigestive oxidants to render membrane-bound proteins of the prey ( insects ) more susceptible to proteolytic attacks.
Since ABL activates a number of cell cycle-controlling proteins and enzymes, the result of the BCR-Abl fusion is to speed up cell division.
Since slow cookers work at temperatures well below boiling point and do not rapidly denature enzymes, vegetables tend to lose trace nutrients.
Since biocatalysis deals with enzymes and microorganisms, it is historically classified separately from " homogeneous catalysis " and " heterogeneous catalysis ".
* Enantioselectivity: Since almost all enzymes are made from L-amino acids, enzymes are chiral catalysts.
Since the body is unable to create the enzymes it needs within the central nervous system it is unable to attach to these gangliosides to break them apart and make them non-toxic.
Since the bran layer, though nutritious, makes the grains tough to chew and contains an enzyme that can cause the oats to go rancid, raw oat groats are often further steam-treated to soften them for a quicker cooking time ( modern " quick oats ") and to denature the enzymes for a longer shelf life.
Since and play
" Since the playwright's wishes were not protected by copyright, Ibsen decided to avoid the danger of being re-written by a lesser dramatist by committing what he called a " barbaric outrage " on his play himself and giving it an alternative ending in which Nora did not leave.
Since the second half of the 20th century, computers have been programmed to play chess with increasing success, to the point where home computers can play chess at a very high level.
Since the invention of the MIDI system in the early 1980s, for example, some people have worked on programs which map MIDI notes to an algorithm and then can either output sounds or music through the computer's sound card or write an audio file for other programs to play.
Since an actual Taiko ensemble had never really performed together and the people he had playing with him were in no way professional musicians, he based the rhythms of their performance on the simplistic arrangement of the shrine music that had been previously played ; which allowed for nearly any person with the interest in Taiko could play along.
Since this affected the rendition of cymbals at playback, sound engineers of the time remedied the situation by asking drummers to play the content of the cymbals onto woodblocks, temple blocks and cowbells for their loudness and short decay.
Since the nuclear pores are located in an area of high traffic, they play an important role in the physiology of cells.
Since independence, Indonesian foreign relations have adhered to a " free and active " foreign policy, seeking to play a role in regional affairs commensurate with its size and location but avoiding involvement in conflicts among major powers.
Since the fruit of the poisonous tree doctrine does not apply to Miranda violations, the exclusionary rule exceptions, attenuation, independent source and inevitable discovery, do not come into play.
Since the two teams play each other so infrequently in the regular season, some, including players on both teams, have questioned whether the Giants and Jets have a real rivalry.
Since girls could play no role in the ministry, and since grammar schools were designed to “ instruct youth so far as they may be fited for the university ,” Latin grammar schools did not accept girls ( nor did Harvard ).
Since the driving force behind helicopters is the rotor disk ( which rotates ), gyroscopic precession comes into play.
Since Rosencrantz & Guildenstern are characters from Hamlet itself, Stoppard's entire play can be considered a piece of metatheatre.
Since the start of interleague play, the A's lead the series 34 – 28.
Since 1997, the term Subway Series has also been applied to interleague play during the regular season between the Yankees and National League New York Mets.
Since interactions between molecules play almost no role, dilute gases form rather trivial solutions.
Since the running game was the key to the Cowboys ' offense, they wanted to take the quick-reacting Buoniconti out of each play.
Since the original run, Shaffer has extensively revised his play, including changes to plot details ; the following is common to all revisions.
Since its inception in 1976, Omaha Children's Museum has been a place where children can challenge themselves, discover how the world works and learn through play.
Since there are no literal mothers in King Lear, Coppélia Kahn provides a psychoanalytic interpretation of the " maternal subtext " found in the play.
Since Welk's show targeted an audience of mature, middle-aged viewers, the band would rarely play tunes from the current charts except strictly as novelty numbers.
Impressed by her performance in this film, but aware of Colbert's sensitivity, David O. Selznick approached her to play the lead role in Since You Went Away ( 1944 ).
Since no play later than A Game at Chess is recorded, it has been hypothesized that his punishment included a ban on writing for the stage.
Since the departure of the Nets to Brooklyn, the Devils are the only major professional sports team to explicitly brand itself as a New Jersey franchise ; although the New York Giants, New York Jets, and New York Red Bulls are headquartered, train, and play in New Jersey, these teams still brand themselves as being from New York City.
Since and significant
Since the psychiatric interview, like any other interview, depends on communication, it is significant to note that the therapist in this interview was a man of marked skill and long experience.
Since 2002 the Victorian Industry has seen a significant decline in catches, with the total allowable catch ( TAC ) reduced from 1440 tonnes to 787 tonnes for the 2011 / 12 fishing year.
Since 1995 the UK government has advised that regular consumption of 3 – 4 units a day for men, or 2 – 3 units a day for women, would not pose significant health risks, but that consistently drinking four or more units a day ( men ), or three or more units a day ( women ), is not advisable.
Since algorithms are platform-independent ( i. e. a given algorithm can be implemented in an arbitrary programming language on an arbitrary computer running an arbitrary operating system ), there are significant drawbacks to using an empirical approach to gauge the comparative performance of a given set of algorithms.
Since 1996 estimates, there has been a significant reduction in the total length of unpaved highway in Botswana-between 1996 and 1999 total length of unpaved highway fell from 14, 139 km to 4, 597 km.
Since 1999, the German parliament has again assembled in Berlin in its original Reichstag building, which dates from the 1890s and underwent a significant renovation under the lead of British architect Sir Norman Foster.
Since the NCC2010 the event is now open to international competition, representing a significant step forward for the ICC.
Since the tropical rainforests are the most diverse ecosystems on Earth and about 80 % of the world's known biodiversity could be found in tropical rainforests, removal or destruction of significant areas of forest cover has resulted in a degraded environment with reduced biodiversity.
Since DBMSs comprise a significant economical market, computer and storage vendors often take into account DBMS requirements in their own development plans.
Since the late 1990s, Dublin has experienced a significant level of net immigration, with the greatest numbers coming from the European Union, especially the United Kingdom, Poland and Lithuania.
Since DBMSs comprise a significant economical market, computer and storage vendors often take into account DBMS requirements in their own development plans.
Since the firearm is also a variable in the accuracy equation, careful tuning of the load to a particular firearm can yield significant
Since the late 1980s, Indonesia has made significant changes to its regulatory framework to encourage economic growth.
Since the 2. 4 GHz band is heavily used to the point of being crowded, using the relatively unused 5 GHz band gives 802. 11a a significant advantage.
Since the war, Kuwait, with the help of the United States and other allies, has made significant efforts to increase the size and modernity of their armed forces.
Since the reunification of Germany, Leipzig has undergone significant change with the restoration of some historical buildings, the demolition of others, and the development of a modern transport infrastructure.
" Since Juliet was born Lammas eve, she came before the harvest festival, which is significant since her life ended before she could reap what she had sown and enjoy the bounty of the harvest, in this case full consummation and enjoyment of her love with Romeo.
Since then there has been a significant expansion primarily due to the " equality movement " and the European Union.
Since 2008 there has been a significant shift by the Malawian government towards accepting investment from China.
Since that time, the palace chambers have received significant damage by looters due to the turmoil in the area.
Since that time, nationalism has become one of the most significant political and social forces in history, perhaps most notably as a major influence or postulate of World War I and especially World War II.
Since 1990, the NTSB has maintained a Most Wanted List of Transportation Safety Improvements, in which it highlights those recommendations that would provide the most significant — and sometimes immediate — benefit to the traveling public.
Since 2007, there has not been any significant mining by the Russian state-owned Arktikugol in Barentsburg.
Since then, scientists have contended that earlier concerns that the devils were the most significant threat to livestock were overestimated and misplaced.
Since the world was viewed as real, not illusory, this doctrine was a significant innovation over and against previous Indian philosophies, which tended to picture the Divine as absolutely transcendent and / or the world as illusion.
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