PrP < sup > C </ sup > is readily digested by proteinase K and can be liberated from the cell surface in vitro by the enzyme phosphoinositide phospholipase C ( PI-PLC ), which cleaves the glycophosphatidylinositol ( GPI ) glycolipid anchor.

* glypiation, glycosylphosphatidylinositol ( GPI ) anchor formation via an amide bond to C-terminal tail

Other anchors include the GPI anchor.

* glypiation, which is the addition of a GPI anchor that links proteins to lipids through glycan linkages.

A special form of glycosylation is the formation of a GPI anchor.

Glycosylphosphatidylinositol () ( GPI anchor ) is a glycolipid that can be attached to the C-terminus of a protein during posttranslational modification.

If a mutation occurs in this gene then PIGA may be defective, which leads to a defect in the GPI anchor.

Several of the proteins that anchor to GPI on the cell membrane are used to protect the cell from destruction by the complement system, and, without these anchors, the cells are more easily targeted by the complement proteins.

Another form of C-terminal modification is the addition of a phosphoglycan, glycosylphosphatidylinositol ( GPI ), as a membrane anchor.

It is usually assumed that prenyl groups ( 3-methyl-but-2-en-1-yl ) facilitate attachment to cell membranes, similar to lipid anchor like the GPI anchor, though direct evidence is missing.

α-agglutinin is the most outer surface protein and is fixed to the cell walls by addition of β-1, 6-glucan, which is the main component of cell walls, to a GPI anchor, which is an anchor to connect β-1, 6-glucan with the cell.

Then the GPI anchor is fixed to the cell membrane and is released.

* PIG Tail ( Phosphatidylinositol glycan ), a membrane anchor for proteins ; more commonly called GPI anchor

In PNH a clonal defect in blood stem cells in the gene PIGA, that is required for GPI synthesis, results in faulty GPI linkage of decay-accelerating factor ( DAF ) and CD59 in red blood cells.

The enzyme phosphatidylinositol glycan A ( PIGA ) is needed to make glycosylphosphatidylinositol ( GPI ), a molecule that anchors proteins to the cell membrane.

The soundtrack of Mark VII Limited's production logo ( the drum roll and the two clinks of the hammer ) is often used while the GPI / Williams Street production card is shown.

The DivX reader is announced, as well as the GPI, which is a GP32 capable of functioning as a video game console, a cell phone, and a PDA.

The genuine progress indicator ( GPI ) is an alternative metric system which is an addition to the national system of accounts that has been suggested to replace, or supplement, gross domestic product ( GDP ) as a metric of economic growth.

The GPI is used in green economics, sustainability and more inclusive types of economics commonly known as " True Cost " economics.

GPI is an attempt to measure whether a country's growth, increased production of goods, and expanding services have actually resulted in the improvement of the welfare ( or well-being ) of the people in the country.

The GDP vs the GPI is analogous to the difference between the gross profit of a company and the net profit ; the Net Profit is the Gross Profit minus the costs incurred.

The best known attempts to apply the concepts of GPI to legislative decisions are probably the GPI Atlantic indicator pioneered by Ronald Colman for Atlantic Canada, the Alberta GPI pioneered by ecological economist Mark Anielski to measure the long-term economic, social and environmental sustainability of the province of Alberta and the environmental and sustainable development indicators used by the Government of Canada to measure its own progress to achieving well-being goals: its Environment and Sustainable Development Indicators Initiative ( Canada ) is a substantial effort to justify state services in GPI terms.

The GPI indicator is based on the concept of sustainable income, presented by economist John Hicks ( 1948 ).

It is relatively straightfoward to measure compared to GPI.

A user still needed three VTRs and a controller to perform A / B roll linear video editing ( LE ), as the Toaster would serve merely as a switcher ( which could be triggered through General Purpose Input / Output ( GPI ) to switch on cue in such a configuration ) but the Toaster itself had no edit controlling capabilities.

Integral and peripheral proteins may be post-translationally modified, with added fatty acid or prenyl chains, or GPI ( glycosylphosphatidylinositol ), which may be anchored in the lipid bilayer.

Proteins with GPI anchors are an exception to this rule and can have purification properties similar to those of integral membrane proteins.

are accessible only to JSTOR and GPI members.

Some of the GPI concepts ( like viewing transforms ) were later incorporated into Windows NT.

* GPI interface-For sending external alarm triggers.

* GPI ( Gemini Planet Imager ), built by a consortium of US and Canadian institutions to fulfil the requirements of the ExAOC Extreme Adaptive Optics Coronagraph proposal.

The axon hillock also functions as a tight junction, since it acts as a barrier for lateral diffusion of transmembrane proteins, GPI anchored proteins such as thy1, and lipids embedded in the plasma membrane.

Kid Ory, the trombonist chicken farmer, is also one of the solid anchor points of jazz.

The author's name " indicates the status of the discourse within a society and culture ", and at one time was used as an anchor for interpreting a text, a practice which Barthes would argue is not a particularly relevant or valid endeavor.

An anchor is a device, normally made of metal, that is used to connect a vessel to the bed of a body of water to prevent the vessel from drifting due to wind or current.

A permanent anchor is used in the creation of a mooring, and is rarely moved ; a specialist service is normally needed to move or maintain it.

A sea anchor is a drogue, not in contact with the seabed, used to control a drifting vessel.

The vessel is attached to the anchor by the rode, which is made of chain, cable, rope, or a combination of these.

Since all anchors that embed themselves in the bottom require the strain to be along the seabed, anchors can be broken out of the bottom by shortening the rode until the vessel is directly above the anchor ( at this point the anchor chain is " up and down " in naval parlance ).

The term aweigh describes an anchor when it is hanging on the rode and is not resting on the bottom.

This is linked to the term to weigh anchor, meaning to lift the anchor from the sea bed, allowing the ship or boat to move.

An anchor is described as aweigh when it has been broken out of the bottom and is being hauled up to be stowed.

Since one fluke always protrudes up from the set anchor, there is a great tendency of the rode to foul the anchor as the vessel swings due to wind or current shifts.

Once the anchor is hauled up to the hawsepipe, the ring end is hoisted up to the end of a timber projecting from the bow known as the cathead.

The crown of the anchor is then hauled up with a heavy tackle until one fluke can be hooked over the rail.