PrP < sup > C </ sup > is readily digested by proteinase K and can be liberated from the cell surface in vitro by the enzyme phosphoinositide phospholipase C ( PI-PLC ), which cleaves the glycophosphatidylinositol ( GPI ) glycolipid anchor.

* glypiation, which is the addition of a GPI anchor that links proteins to lipids through glycan linkages.

A special form of glycosylation is the formation of a GPI anchor.

Glycosylphosphatidylinositol () ( GPI anchor ) is a glycolipid that can be attached to the C-terminus of a protein during posttranslational modification.

In PNH a clonal defect in blood stem cells in the gene PIGA, that is required for GPI synthesis, results in faulty GPI linkage of decay-accelerating factor ( DAF ) and CD59 in red blood cells.

The enzyme phosphatidylinositol glycan A ( PIGA ) is needed to make glycosylphosphatidylinositol ( GPI ), a molecule that anchors proteins to the cell membrane.

Another form of C-terminal modification is the addition of a phosphoglycan, glycosylphosphatidylinositol ( GPI ), as a membrane anchor.

The GPI anchor is attached to the C-terminus after proteolytic cleavage of a C-terminal propeptide.

The soundtrack of Mark VII Limited's production logo ( the drum roll and the two clinks of the hammer ) is often used while the GPI / Williams Street production card is shown.

The DivX reader is announced, as well as the GPI, which is a GP32 capable of functioning as a video game console, a cell phone, and a PDA.

The genuine progress indicator ( GPI ) is an alternative metric system which is an addition to the national system of accounts that has been suggested to replace, or supplement, gross domestic product ( GDP ) as a metric of economic growth.

GPI is an attempt to measure whether a country's growth, increased production of goods, and expanding services have actually resulted in the improvement of the welfare ( or well-being ) of the people in the country.

The GDP vs the GPI is analogous to the difference between the gross profit of a company and the net profit ; the Net Profit is the Gross Profit minus the costs incurred.

The best known attempts to apply the concepts of GPI to legislative decisions are probably the GPI Atlantic indicator pioneered by Ronald Colman for Atlantic Canada, the Alberta GPI pioneered by ecological economist Mark Anielski to measure the long-term economic, social and environmental sustainability of the province of Alberta and the environmental and sustainable development indicators used by the Government of Canada to measure its own progress to achieving well-being goals: its Environment and Sustainable Development Indicators Initiative ( Canada ) is a substantial effort to justify state services in GPI terms.

The GPI indicator is based on the concept of sustainable income, presented by economist John Hicks ( 1948 ).

It is relatively straightfoward to measure compared to GPI.

Several of the proteins that anchor to GPI on the cell membrane are used to protect the cell from destruction by the complement system, and, without these anchors, the cells are more easily targeted by the complement proteins.

Supporters of GPI would respond that GDP, when used as a measure of societal well-being, ends up defining well-being to be things that the supporters of GDP ideologically support, and cannot function to measure the goals of a diverse, plural society.

GPI takes account of these problems by incorporating sustainability: whether a country's economic activity over a year has left the country with a better or worse future possibility of repeating at least the same level of economic activity in the long run.

This later work resulted yet an other macroeconomic indicator Genuine Progress Indicator ( GPI ): see sustainability measurement.

The GPI is an extension of ISEW, that stresses genuine and real progress of the society and seeks especially to monitor welfare and the ecological sustainability of the economy.

OS / 2 also had more powerful drawing functions in its Graphics Programming Interface ( GPI ).

GPI advocates claim that it can more reliably measure economic progress, as it distinguishes between worthwhile growth and uneconomic growth.

However GDP tends to be reported as synonymous with economic progress by journalists and politicians and the GPI seeks to correct this shorthand by providing a more encompassing measure.

Supporters of GDP as a measure of societal well-being claim that competing measures such as GPI are more vulnerable to political manipulation.

* PIG Tail ( Phosphatidylinositol glycan ), a membrane anchor for proteins ; more commonly called GPI anchor

A user still needed three VTRs and a controller to perform A / B roll linear video editing ( LE ), as the Toaster would serve merely as a switcher ( which could be triggered through General Purpose Input / Output ( GPI ) to switch on cue in such a configuration ) but the Toaster itself had no edit controlling capabilities.

Integral and peripheral proteins may be post-translationally modified, with added fatty acid or prenyl chains, or GPI ( glycosylphosphatidylinositol ), which may be anchored in the lipid bilayer.

Proteins with GPI anchors are an exception to this rule and can have purification properties similar to those of integral membrane proteins.

Other anchors include the GPI anchor.

are accessible only to JSTOR and GPI members.

Some of the GPI concepts ( like viewing transforms ) were later incorporated into Windows NT.

* GPI interface-For sending external alarm triggers.

If a mutation occurs in this gene then PIGA may be defective, which leads to a defect in the GPI anchor.

* GPI ( Gemini Planet Imager ), built by a consortium of US and Canadian institutions to fulfil the requirements of the ExAOC Extreme Adaptive Optics Coronagraph proposal.

The axon hillock also functions as a tight junction, since it acts as a barrier for lateral diffusion of transmembrane proteins, GPI anchored proteins such as thy1, and lipids embedded in the plasma membrane.

In the first instance, `` mimesis '' is here used to mean the recalling of experience in terms of vivid images rather than in terms of abstract ideas or conventional designations.

A dominant motive is the poet's longing for his homeland and its boyhood associations: `` Not men-folk, but the fields where I would stray, The stones where as a child I used to play ''.

So in these pages the term `` technology '' is used to include any and all means which could amplify, project, or augment man's control over himself and over other men.

But what a super-Herculean task it is to winnow anything of value from the mud-beplastered arguments used so freely, particularly since such common use is made of cliches and stereotypes, in themselves declarations of intellectual bankruptcy.

This text from Dr. Huxley is sometimes used by enthusiasts to indicate that they have the permission of the scientists to press the case for a wonderful unfoldment of psychic powers in human beings.

The men who speculate on these institutions have, for the most part, come to at least one common conclusion: that many of the great enterprises and associations around which our democracy is formed are in themselves autocratic in nature, and possessed of power which can be used to frustrate the citizen who is trying to assert his individuality in the modern world ''.

Properly used, the present book is an excellent instrument of enlightenment.

This prospect did not please Mrs. King any more than did the possibility that her daughter might marry a Bohemian, but she used it to suggest to Thompson that, `` It is not in her nature to love you ''.

On the other hand, the consensus of opinion is that, used with caution and in conjunction with other types of evidence, the native sources still provide a valid rough outline for the English settlement of southern Britain.

The trouble with this machinery is that it is not used and the reason that it is not used is the absence of a conscious sense of community among the free nations.

In addition to his experiments in reading poetry to jazz, Patchen is beginning to use the figure of the modern jazz musician as a myth hero in the same way he used the figure of the private detective a decade ago.

When different colors are used, she is just as likely to color trees purple, hair green, etc..

Berlin is merely being used by Moscow as a stalking horse.

The collection of information is meaningless unless it is understood and used for a definite purpose.

This is used as a reference for comparing the ohmic heating and the electrical energy obtained from the measured current through the element and the measured voltage across the element.