When Fred Powell's brother-in-law, Charlie Keane, moved into the dead man's home, the anonymous letter writer took no chances on Charlie taking up where Fred had left off and wasted no time on a first notice:

An accompanying sympathetic letter explained that inside the envelope was a name for Mrs. Coolidge's first granddaughter.

the `` sober opinion '' of his letter to Noyes, written when Hardy was eighty years old, is essentially that of his first `` philosophical '' notebook entry, made when he was twenty-five: `` The world does not despise us: it only neglects us '' ( Early Life, p. 63 ).

A ( named a, plural aes ) is the first letter and vowel in the ISO basic Latin alphabet.

The earliest certain ancestor of " A " is aleph ( also called ' aleph ), the first letter of the Phoenician alphabet ( which, by consisting entirely of consonants, is an abjad rather than a true alphabet ).

Alpha ( uppercase Α, lowercase α ; Álpha ) is the first letter of the Greek alphabet.

Plutarch, in Moralia, presents a discussion on why the letter alpha stands first in the alphabet.

If the original word was capitalised, then the first letter of its abbreviation should retain the capital, for example Lev.

* 1527 – The first known letter from North America is sent by John Rut while at St. John's, Newfoundland.

The first nine probably date from the 3rd century BC, they are usually included among the Cynic epistles, and reflect how the Cynic philosophers viewed him as prefiguring many of their ideas ; the tenth letter is quoted by Diogenes Laertius, it is addressed to Croesus, the proverbially rich king of Lydia, it too is fictitious:

The first significant reference to the influence of Aelian in the 16th century is a letter to Maurice of Nassau, Prince of Orange from his cousin William Louis, Count of Nassau-Dillenburg on December 8, 1594.

The first level of the code indicates the anatomical main group and consists of one letter.

* A ( Cyrillic ), the first letter of the Early Cyrillic alphabet

Athanasius ' letters include one " Letter Concerning the Decrees of the Council of Nicaea " ( De Decretis ), which is an account of the proceedings of that council, and another letter in the year 367 which was the first known listing of the New Testament including all those books now accepted everywhere as the New Testament.

St Cyril of Alexandria, 370-444, In the first letter says: " Athanasius is one who can be trusted: he would not say anything that is not in accord with sacred scripture.

The Beowulf manuscript itself is mentioned in name for the first time in a letter in 1700 between George Hickes, Wanley ’ s assistant, and Wanley.

The letter stated her objections to Muslims in France ritually slaughtering sheep by slitting their throats without anesthetizing them first but also said, in reference to Muslims, that she was " fed up with being under the thumb of this population which is destroying us, destroying our country and imposing its habits ".

When writing the scientific name of an organism, it is proper to capitalize the first letter in the genus and put all of the specific epithet in lowercase.

The first four poems ( chapters ) are acrostics, like some of the Psalms ( 25, 34, 37, 119 ), i. e., each verse begins with a letter of the Hebrew alphabet taken in order.

The theory was first published in April 1957 in the letter, " Microscopic theory of superconductivity ".

The idea of a body so massive that even light could not escape was first put forward by geologist John Michell in a letter written to Henry Cavendish in 1783 of the Royal Society:

The first recorded use of the term is in a 1964 letter by Anne Ewing to the American Association for the Advancement of Science.

Tomislav was the first ruler of Croatia who was styled a king in a letter from the Pope John X, dating kingdom of Croatia to year 925.

A woman doctor wrote to a friend in June 1933 that she had not yet become a cannibal, but was “ not sure that I shall not be one by the time my letter reaches you .” The good people died first.

The first letter of a chemical symbol is always capitalized, as in the preceding examples, and the subsequent letters, if any, are always lower case ( small letters ).

but let the twenty-five thousand and first butchery be the signal for the arrest of the 50 state highway commissioners.

At two thirty he sent Fujimoto to the top of the wall at the northeast corner of the mission to keep an eye on the ridge road and give a signal when he first glimpsed the approach of Kayabashi's party.

By this scheme, pulling one signal to clear locks all the other switch and signal levers in safe positions until the first signal is again restored to normal.

A high enough opening bid could signal a player's determination to be first ranked in that attribute, thereby dissuading others from competing.

The 5200 also featured the innovation of the first automatic TV switchbox, allowing it to automatically switch from regular TV viewing to the game system signal when the system was activated.

The first step is usually to convert the signal from an analog to a digital form, by sampling and then digitizing it using an analog-to-digital converter ( ADC ), which turns the analog signal into a stream of numbers.

Digital video was first introduced commercially in 1986 with the Sony D-1 format, which recorded an uncompressed standard definition component video signal in digital form instead of the high-band analog forms that had been commonplace until then.

DARPA supported the evolution of the ARPANET ( the first wide-area packet switching network ), Packet Radio Network, Packet Satellite Network and ultimately, the Internet and research in the artificial intelligence fields of speech recognition and signal processing, including parts of Shakey the robot.

When the power supply to the amplifier is first switched on, electronic noise in the circuit provides a signal to get oscillations started.

In the 1970s, the ground-based Omega Navigation System, based on phase comparison of signal transmission from pairs of stations, became the first worldwide radio navigation system.

The first test of the weather control system goes awry when the remote control for a radioactive balloon is jammed by an unexplained signal coming from the center of the island.

Although digitizing can be the first step in cleaning up a signal, it does not, by itself, improve the quality.

It also announced that the first OS, PRS and SoL signal will be available in 2013 and the CS and SOL sometime later.

The first commercial LEDs were commonly used as replacements for incandescent and neon indicator lamps, and in seven-segment displays, first in expensive equipment such as laboratory and electronics test equipment, then later in such appliances as TVs, radios, telephones, calculators, and even watches ( see list of signal uses ).

* 1896 – A. S. Popov makes the first radio signal transmission in history.

This voltage has two functions: first, it provides a power source for an assortment of voltage-dependent protein machinery that is embedded in the membrane ; second, it provides a basis for electrical signal transmission between different parts of the membrane.

On April 25, 2012, the Ecuadorian Space Agency announced that due a technological change in the video camera of its first satellite it will be adding a 3rd mission, which is to help organizations and individuals around the world monitor for small, most dangerous near-earth objects directly from orbit in real time and help fine tune the catalog of orbital debris by injecting the live video signal of the satellite into the Internet, thus turning the NEE-01 Pegasus in the first online, real-time video orbital sentry.

* RMS Republic of 1903, the second White Star liner to bear the name, and the first ship ever to signal distress by wireless telegraphy, lost after colliding with the SS Florida

For example, albumin is first synthesized as preproalbumin and contains an uncleaved signal peptide.

In contrast to secretory proteins, the first transmembrane domain acts as the first signal sequence, which targets them to the ER membrane.