Frustrated with their lack of concern for quality, Chaplin joined forces with Douglas Fairbanks, Mary Pickford, and D. W. Griffith to form a new distribution company — United Artists, established in January 1919.

Part V of this act established an amending formula for the Canadian constitution, the lack of which ( due to more than 50 years of disagreement between the federal and provincial governments ) was the only reason Canada's constitutional amendments still required approval by the British parliament after ratification of the Statute of Westminster in 1931.

The remoteness of the region and the lack of a Gaelic-speaking clergy undermined the missionary efforts of the established church.

The new arrivals included many middle-class families who moved into towns and established small businesses and workshops — although lack of economic opportunities meant that approximately a quarter later left Palestine.

However, very few cartridges, a small screen, and a lack of support from established home video game companies led to its demise in.

Besides its established role as a diagnostic technique, PET has an expanding role as a method to assess the response to therapy, in particular, cancer therapy, where the risk to the patient from lack of knowledge about disease progress is much greater than the risk from the test radiation.

Disappointed with the lack of interest from government in Mars exploration and after the success of his book The Case for Mars as well as leadership experience at the National Space Society, Zubrin established the Mars Society in 1998.

No link was ever established between Negri and the Red Brigades and almost all of the charges against him ( including 17 murders ) were dropped within months of his arrest due to lack of evidence.

The American Medical Association ( AMA ) has stated that because of the lack of scientific evidence, based on well-controlled clinical trials, that supports a cause-and-effect relationship between exposure to very low levels of chemicals and the myriad symptoms reported by clinical ecologists, MCS is not recognized as an established organic disease.

Over the last century, occasional spiders have been intercepted in various states where they have no known established populations ; these spiders may be transported fairly easily, though the lack of established populations well outside the natural range also indicates that such movement has not led to colonization of new areas, after decades of opportunities.

The theory of Permanent Revolution addressed the question of how such feudal regimes were to be overthrown, and how socialism could be established given the lack of economic prerequisites.

A successful AIDS prevention and treatment program was also established, leading the Catholic Institute for International Relations to state, the " incredible feat of slowing the rate of new infections in Haiti has been achieved despite the lack of international aid to the Haitian government, and despite the notable lack of resources faced by those working in the health field.

The Great Trek was encouraged by discontent with British rule, the economic changes caused by anti-slavery laws, lack of protection against raiding Xhosa bands, and Anglicisation of established Dutch traditions.

During the 1980s, the RSA worked with the Comino Foundation and established a Comino Fellowship Committee ' to change the cultural attitude to industry from one of lack of interest or dislike to one of concern and esteem '.

Second, the lack of a widely used symbolism to replace the already established terminology of ratios delayed the full acceptance of fractions as alternative until the 16th century.

Despite being one of the most studied proteins in biology, its true physiological function is not yet conclusively established: mice genetically engineered to lack myoglobin are viable, but showed a 30 % reduction in cardiac systolic output.

A house of Dominican friars was established at Smithfield, but this was only possible through importing professed religious from Holland and Spain, and Mary's hopes of further refoundations foundered, as she found it very difficult to persuade former monks and nuns to resume the religious life ; consequently schemes for restoring the abbeys at Glastonbury and St Albans failed for lack of volunteers.

" ( This lack of a degree may have hurt Fessenden's employment opportunities ; when McGill University established an electrical engineering department, Fessenden was turned down on an application to be the chairman, in favor of an American.

Six months after The Inquirer was founded, with competition from eight established daily newspapers, lack of funds forced Norvell and Walker to sell the newspaper to publisher and United States Gazette associate editor Jesper Harding.

A Baptist group had been established in the 1820s, but ended due to a lack of support.

The town was developed in the 1950s and established in 1958 primarily by M. Penn Phillips and the Holly Sugar Corporation as a resort community on the Salton Sea, a saline, endorheic rift lake located directly on the San Andreas Fault, yet very little development was achieved due to its isolation and lack of local employment opportunities.

The Presbyterian Church established in 1737 was a focal point for the community, and the lack of serious injuries when the church's balcony collapsed in 1759 was deemed to be an example of Divine Intervention, leading residents to change the area's name to New Providence.

This story is often repeated despite a lack of evidence, and runs contrary to the established pattern of Ford ( who was born and raised in Detroit ) starting all of his businesses in Detroit.

A review of the methods used in trials of antipsychotics, despite stating that the overall quality is " rather good ," reported issues with the selection of participants ( including that in schizophrenia trials up to 90 % of people who are generally suitable do not meet the elaborate inclusion and exclusion criteria, and that negative symptoms have not been properly assessed despite companies marketing the newer antipsychotics for these ); issues with the design of trials ( including pharmaceutical company funding of most of them, and inadequate experimental " blinding " so that trial participants could sometimes tell whether they were on placebo or not ); and issues with the assessment of outcomes ( including the use of a minimal reduction in scores to show " response ," lack of assessment of quality of life or recovery, a high rate of discontinuation, selective highlighting of favorable results in the abstracts of publications, and poor reporting of side-effects ).

Skeptics claim that there is a lack of a viable theory of the mechanism behind ESP, and that there are historical cases in which flaws have been discovered in the experimental design of parapsychological studies.

" He felt that his relative lack of experience left him without the necessary design tools to refine his vision, but the community liked the city hall enough to invite him back.

A major drawback of current gesture interaction solutions is the lack of support for two necessary user interface design principles, feedback and visibility ( or affordance ).

This is variously blamed on aggressive driving, insufficient driver training, old and unsafe cars, inferior road design and construction, and a lack of appreciation of the skill and responsibility required to safely operate a motor vehicle.

This design places an exceeding demand upon precision engineering due to the lack of pneumatics.

The number of losers — which may add up to the size and severity of poverty — can be unexpectedly large if the method and process of privatization and how it is implemented are seriously flawed ( e. g. lack of transparency leading to state-owned assets being appropriated at minuscule amounts by those with political connections, absence of regulatory institutions leading to transfer of monopoly rents from public to private sector, improper design and inadequate control of the privatization process leading to asset stripping.

Without at least one of these two pieces of information, we are not obviously justified in seeing design in such cases … he problem for the fine-tuning argument is that we lack both of the pieces that are needed to justify an inference of design.

The lack of design guidelines in X has resulted in several vastly different interfaces, and in applications that have not always worked well together.

In November 1974, Science for the People went public with their objections to the Boston XYY study in a press conference and a New Scientist article alleging inadequate informed consent, a lack of benefit ( since no specific treatment was available ) but substantial risk ( by stigmatization with a false stereotype ) to the subjects, and that the unblinded experimental design could not produce meaningful results regarding the subjects ' behavior.

) The lack of interoperability can be a consequence of a lack of attention to standardization during the design of a program.

Some cite design limitations and a lack of methodological rigor, while others assert that the quality is improving and that when suitable assessment criteria are applied, scientific evidence supports the therapeutic value of meditation.

Some cite design limitations and a lack of methodological rigor, while others assert that the quality is improving and that when suitable assessment criteria are applied, scientific evidence supports the therapeutic value of meditation.

The lack of complete and reliable information as to whom the credit for the design belongs, led to innumerable speculations.

Unable to produce the design himself due to lack of funding, he sold the patent in 1908 to William Henry Hoover who had Spangler's machine redesigned with a steel casing, casters, and attachments.

Still, there are many cases in which designers wish to sequence the steps of their models but lack the means to design clear diagrams.

Despite no widespread regulation, and even with a lack in many cases of national-level regulation, heraldry has remained rather consistent across Europe, where traditions alone have governed the design and use of arms.

* the lack of concern about security and authentication in the design, deployment and operation of some existing SCADA networks

The service was later dropped in 1965, owing to lack of cycle traffic and possibly the design.

A combination of hardware and operating-system software design considerations determine the symmetry ( or lack thereof ) in a given system.

Meanwhile Komarov and his fellow cosmonauts had their groups and assignments constantly revised and they became increasingly anxious about the lack of response to their concerns about the design and manufacture of space craft which had been raised in a letter to Leonid Brezhnev by Yuri Gagarin on their behalf.

** Federico Faggin, having finished the design of the 4004, became leader of the project from January 1971 until its successful completion in April 1972, after it had been suspended – for lack of progress – for about seven months.

The freeze on design in 1943 meant that the computer design would lack some innovations that soon became well-developed, notably the ability to store a program.