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major and spliceosome
: The minor spliceosome is very similar to the major spliceosome, however it splices out rare introns with different splice site sequences.
While the minor and major spliceosomes contain the same U5 snRNP, the minor spliceosome has different, but functionally analogous snRNPs for U1, U2, U4, and U6, which are respectively called U11, U12, U4atac, and U6atac.
Like the major spliceosome, it is only found in the nucleus.
There are two different forms of the spliceosome, the major and minor forms.
The ncRNA components of the major spliceosome are U1, U2, U4, U5, and U6.
The snRNAs that make up the major spliceosome are named U1, U2, U4, U5, and U6, and participate in several RNA-RNA and RNA-protein interactions.
The minor spliceosome is located in the nucleus like its major counterpart, though there are exceptions in some specialised cells including anucleate platelets and the dendroplasm of neuronal cells.

major and containing
a middle distance often containing the major motif ; ;
The major biological source of sulfur containing compounds is dimethyl sulfide.
Although this selected translation is not generally quoted by members of the Church, the English Bible issued by the Church and commonly used by Latter-day Saints contains cross references to the Joseph Smith Translation ( JST ), as well as an appendix containing major excerpts from it.
A major innovation in small arms and light artillery came in the second half of the 19th century when ammunition, previously delivered as separate bullets and powder, was combined in a single metallic ( usually brass ) cartridge containing a percussion cap, powder, and a bullet in one weatherproof package.
Hispaniola ( Spanish: La Española ) is a major island in the Caribbean, containing the two sovereign states of the Dominican Republic and Haiti.
A study was done on two major databases containing hedge fund data.
In total there are about 400 surviving manuscripts containing Old English text, 189 of them considered major.
The Brown Corpus was the first major database available, containing several million words.
A major tourist attraction is the medieval town of Gruyères with its castle, containing a regional museum and an arts museum.
The main site at Meyrin has a large computer centre containing powerful data-processing facilities, primarily for experimental data analysis ; because of the need to make these facilities available to researchers elsewhere, it has historically been a major wide area networking hub.
This produces a slight separation between the molecules containing < sup > 235 </ sup > U and < sup > 238 </ sup > U. Throughout the Cold War, gaseous diffusion played a major role as a uranium enrichment technique, and as of 2008 accounted for about 33 % of enriched uranium production, but is now an obsolete technology that is steadily being replaced by the later generations of technology as the diffusion plants reach their ends-of-life .< ref >
Dolenz also released 2 CD's on the Kid Rhino label, " Micky Dolenz Puts You to Sleep " ( containing Dolenz chosen songs originally released by many major artists, given a " dreamy " touch too ) and " Broadway Micky " ( Dolenz singing choice Broadway standards ).
Patients with diabetes who continued to take anti-diabetes drugs containing niacin did not experience major blood glucose changes.
The major raw material for the clinker-making is usually limestone ( CaCO < sub > 3 </ sub >) mixed with a second material containing clay as source of alumino-silicate.
For example, when in the key of C-sharp minor or E major, F, C, G, and D contain a sharp ; adding a double accidental ( double sharp ) to F for example in this case would only raise the already sharp containing note F one half step or semitone, creating G natural, respectively.
Before the Divine Liturgy on this day, a special service, known as the " Triumph of Orthodoxy " is held in cathedrals and major monasteries, at which the synodicon ( containing anathemas against various heresies, and encomia of those who have held fast to the Christian faith ) is proclaimed.
The three-party ( i. e. six plus some purely Flemish and Walloon parties ) political systems got disturbed by the Green parties ( the Dutch-speaking Agalev, now Groen !, and the French-speaking Ecolo ) in the 1980s which took a lot of influence after the Marc Dutroux Scandal and the " dioxin affair ", a food scandal ( chickens containing dioxin levels far above the maximum allowed ) which would not have had any major repercussions, had it not erupted just days before the elections.
Archaeological work at the Ruins of Yin ( near modern day Anyang ), which has been identified as the last Shang capital, uncovered eleven major Yin royal tombs and the foundations of palaces and ritual sites, containing weapons of war and remains from both animal and human sacrifices.
Ultramarine is the most complex of the mineral pigments, a complex sulfur-containing sodio-silicate ( Na < sub > 8-10 </ sub > Al < sub > 6 </ sub > Si < sub > 6 </ sub > O < sub > 24 </ sub > S < sub > 2-4 </ sub >) containing a blue cubic mineral called lazurite ( the major component in lapis lazuli ).
The first major shipment of CONEXes, containing engineering supplies and spare parts, was made by rail from the Columbus General Depot in Georgia to the Port of San Francisco, then by ship to Yokohama, Japan, and then to Korea, in late 1952 ; shipment times were almost halved.
The protein tyrosine kinase pp125 is one of the major phosphotyrosine – containing proteins in unaffected ( untransformed ) avian and rodent fibroblast cells ( fibroblast cells are explained above in some detail ).
Niches with pointed arches and containing statuary are a major external feature.
Approximately 158 Banawá people live in one major village and two smaller settlements containing a single extended family each.
The first major update to the NGC is the Index Catalogue of Nebulae and Clusters of Stars ( abbreviated as IC ), published in two parts by Dreyer in 1895 ( IC I, containing 1, 520 objects ) and 1908 ( IC II, containing 3, 866 objects ).

major and at
The cost of developing a major weapon system is now so enormous that the greatest care must be exercised in selecting new systems for development, in determining the most satisfactory rate of development, and in deciding the proper time at which either to place a system into production or to abandon it.
The total value of our industry's shipments, at factory prices, increased from $9.2 billion in 1959 to approximately $10.1 billion as a result of increases in all of the major segments of our business -- home entertainment, military, industrial, and replacement.
Mason and Taylor both show that the major axis of the ellipsoids is at 45-degrees at low rates of shear and that it approaches the direction of shear with increased rates of shear.
If A is the major axis of an ellipsoid and B and C are the other two axes, the radius of curvature in the ab plane at the end of the axis Af, and the difference in pressure along the A and B axes is Af.
While roleplaying for testing is not too well understood at the present time, it represents one of the major uses of this procedure.
Similarly, at the opposite end of the market cycle, towards the end of an intermediate or major decline, usually while the bottom is being formed on the price chart, it is characteristic that an increase is noticed in odd-lot selling again alerting the chartist that a bottom is becoming a greater likelihood.
Raymond Vernon reports that residents of East St. Louis have been driving across the Mississippi, through the heart of downtown St. Louis and out to the western suburbs for major shopping, simply because parking is easier at the big branches than it is in the heart of town.
As the child addresses the shepherd in a dream, light -- in the form of the major mode -- begins to appear, and at the moment of the miracle we hear a clear and shining D major.
Since experience indicates that effluents from oxidation ponds do not create major problems at these BOD concentrations, the goal for the effluent quality of the accelerated treatment system was the same as from conventional oxidation ponds.
Because the rake angle Af at the tip of the knife is very much smaller ( or even negative ) when compared to the value of **yc for the major portion of the knife, a very rapid increase in cutting force with thickness will result.
Even though it was known that the Luftwaffe in the north was now being directed by the young and energetic General Peltz, the commander who would conduct the `` Little Blitz '' on London in 1944, a major raid on Bari at this juncture of the war was not to be considered seriously.
He finished the war as a major general, commanding a full division, and at 25 was the youngest major general in the history of the U.S. Army.
Not satisfied with various unofficial checks on the liveliness of baseballs currently in use, the major leagues have ordered their own tests, which are in progress at Massachusetts Institute of Technology.
a review of the philosophy of Communist leaders by Ted Slack, another real estate agent who became interested as a philosophy major at the University of Miami ; ;
The population of the Congo is 13.5 million, divided into at least seven major `` culture clusters '' and innumerable tribes speaking 400 separate dialects.
Another major church body had 4,499,608 members and twenty years later its membership stood at 4,622,444.
Charles ' recording is very commonly played at major sporting and entertainment events, such as the Super Bowl, and WrestleMania 2 ; Charles gave a live performance of the song prior to Super Bowl XXXV, the last Super Bowl played before the September 11 terrorist attacks, as well as during Game 2 of the 2001 World Series after the attacks.
* 1915 – World War I: Battle of Sari Bair – the Allies mount a diversionary attack timed to coincide with a major Allied landing of reinforcements at Suvla Bay.
During its preparation he became a friend of Cosima Wagner ( then in Strasbourg ), with whom he had many theological and musical conversations, exploring his view of Bach's descriptive music, and playing the major Chorale Preludes for her at the Temple Neuf.
He received a brevet promotion to lieutenant colonel in the regular army for his actions at Antietam and was promoted in March 1863 to major general of volunteers, to rank from November 29, 1862.
In 1710 he convinced the Ottoman Sultan Ahmed III to declare war against Russia, and the Ottoman forces under Baltacı Mehmet Pasha won a major victory at the Battle of Prut.
By 1094, Yusuf had annexed most major taifas, with the exception of the one at Zaragoza.

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