Benzodiazepines share a similar chemical structure, and their effects in humans are mainly produced by the allosteric modification of a specific kind of neurotransmitter receptor, the GABA < sub > A </ sub > receptor, which increases the conductance of this inhibitory channel ; this results in the various therapeutic effects as well as adverse effects of benzodiazepines.

Above a certain threshold size, which varies with planetary gravity, the collapse and modification of the transient cavity is much more extensive, and the resulting structure is called a complex crater.

Epigenetic chemical modification of the structural proteins in chromatin also alter the local chromatin structure, in particular chemical modifications of histone proteins by methylation and acetylation.

Once this post-translational modification process has been completed, the protein begins to fold ( sometimes spontaneously and sometimes with enzymatic assistance ), curling up on itself so that hydrophobic elements of the protein are buried deep inside the structure and hydrophilic elements end up on the outside.

Some modification of the Feynman rules of calculation may well outlive the elaborate mathematical structure of local canonical quantum field theory ...” So far there are no opposing opinions.

The free-electron debacle showed researchers that the model assuming that the ions were in a sea of free electrons needed modification, and so a number of quantum mechanical models such as band structure calculations based on molecular orbitals or the density functional theory were developed.

In addition to those listed above, the most important modification of primary structure is peptide cleavage ( See: Protease ).

Secondly, is it possible that an animal having, for instance, the structure and habits of a bat, could have been formed by the modification of some animal with wholly different habits?

The modification of the ions has a dramatic effect on the structure of the cages.

** Genetic engineering – deliberate modification of the genetic structure of an organism.

The modification of starches in the flour allows the use of wetter doughs ( making for a moister end product ) without destroying the structure necessary for light fluffy cakes and biscuits.

Rearrangement of the chromatin structure via DNA methylation or histone modification may play a role as well.

It is thought that they achieve this through alterations in chromatin structure, such as histone modification and DNA methylation, to restrict or permit the transcription of target genes.

Years of renovation and modification have all but disguised the original structure, which originally possessed an open portico.

The bottom of this diagram shows the modification of primary structure of insulin, as described.

Another departure is a modification, if not a refinement, of the grid structure Martin has used since the late 1950s.

The key structural modification, which was carried through to essentially all subsequent beta blockers, was the insertion of an oxymethylene group into the arylethanolamine structure of pronethalol thus greatly increasing the potency of the compound.

Code can often be copied without modification from one to the other, and programmers familiar with one can easily understand the syntax and structure of code in the other.

Burimamide was still insufficiently potent for oral administration and further modification of the structure, based on modifying the acid dissociation constant of the compound, led to the development of metiamide.

A surface structure can be generated that is biologically attachable by surface modification using laser pulses, allowing better joining with bone.

The iron-poor ( magnesium-rich ) modification of armacolite has the same crystal structure and occurs in the Earth's crust as the mineral karrooite.

This covalent modification of the molecular structure of Cdc2 inhibits the enzymatic activity of Cdc2 and prevents cell division.

Modification time and space are bounded by the size of the structure, since a single modification may cause the entire structure to be copied.

The nearly free electron model is a modification of the free electron model which includes a weak periodic perturbation meant to model the interaction between the conduction electrons and the ions in a crystalline solid.

Its cause is a complex interaction between the differing surface tensions of water and ethanol ; it is induced by a combination of surface tension modification of water by ethanol together with ethanol evaporating faster than water.

Vagrant Story is unique as a console action / adventure role-playing game in that it features no shops and no player interaction with other characters ; instead, the game focuses on weapon creation and modification, as well as elements of puzzle-solving and strategy.

Modern active solar water systems have electronic controllers that offer a wide-range of functionality, such as the modification of settings that control the system, interaction with a backup electric or gas-driven water heater, calculation and logging of the energy saved by a SWH system, safety functions, remote access, and various informative displays, such as temperature readings.

MOND can also be interpreted as a modification of inertia, perhaps due to an interaction with vacuum energy, and such a trajectory-dependent theory could account for the different accelerations apparently acting on the orbiting planets and the Pioneer craft on their escape trajectories.

Selective modification of the retinaldehyde structure, particularly the density of electrons in the π-orbitals, can lead to insights into the interaction between the retinaldehyde moiety and the surrounding pigment protein.

Because nitrous oxide ( NO ) is involved in stimulating the synthesis of cGMP, further research is being conducted to understand the physiological interaction of NO with CNG channels, particularly in the covalent modification of CNG channels in OSNs.

These proteins contain a number of known common modification domains, including regions for divalent cation interaction, phosphorylation & acetylation, and proteolytic cleavage, among others established and predicted.

Genetically modified animals currently being developed can be placed into six different broad classes based on the intended purpose of the genetic modification:

In response, Kildall pioneered the concept of a BIOS, a set of simple programs stored in the computer hardware which enabled CP / M to run on different systems without modification.

When iodine is dissolved in polar solvents which are strong donor solvents such as ketones, ethers, pyridine, the formation of charge-transfer complex leads to modification of the energy gap between the two molecular orbitals, thus different wavelengths were absorbed and iodine has different color in solvents with different polarity.

The logo was given yet another modification in 1974, with the number of stars being reduced to 22, and the Paramount text and Gulf + Western byline appearing in different fonts.

Genotypes often have much flexibility in the modification and expression of phenotypes ; in many organisms these phenotypes are very different under varying environmental conditions ( see ecophenotypic variation ).

* Adding new concrete types is done by modifying the client code to use a different factory, a modification that is typically one line in one file.

As an alternative to porting, cross-platform virtualization allows applications compiled for one CPU and operating system to run on a system with a different CPU and / or operating system, without modification to the source code or binaries.

They include Deuces Wild, where a two serves as a wild card, pay schedule modification, where four aces with a five or smaller kicker pays an enhanced amount ( these games usually have some adjective in the title such as " bonus ", " double ", or " triple "); and multi-play poker, where the player starts with a base hand, and each additional played hand draws from a different set of cards with the base hand.

A slightly changed version of MR was the official system for Korean in South Korea from 1984 to 2000, and yet a different modification is still the official system in North Korea.

The images of the worms themselves can be transformed into completely different characters, although their movement animations are less flexible regarding modification.

Minor ( and not-so-minor ) rule modification has sprouted a number of different variations on Alice Chess.

Sometimes a manager may combine two different recipes or adapt an existing recipe with some important modification to meet a situation at hand.

These have been dealt with by various translators with different degrees of modification to the meaning of the original text.

Pressurized burner stoves are now available that are capable of burning multiple fuels or volatile liquids with little or no modification ( due to variability in the volatility of different fuels, the " jets " of multi-fuel stoves may need to be changed according to the type of fuel used ), including alcohol, gasoline or other motor fuels, kerosene, jet propellant, and many others.

A slightly modified version of MR was the official system for Korean in South Korea from 1984 to 2000, and yet a different modification is still the official system in North Korea.

: A tool intended to handle the general relations between different models, including the metadata on each model ( e. g. author, date of creation or modification, method of creation ( which tool?

While all the manufacturers ' track was the same size and the trains and buildings approximately the same scale, the couplers for the most part remained incompatible, making it impossible to mix train cars from different manufacturers without modification.

The first assignment he attaches himself to is an attempted separatist secession by followers of the Transient movement ( a group of people who use genetic body modification based on alien DNA to become a completely different species, forced to live in the Angels 8 slum district ) led by Fred Christ, a former rock group manager and impresario similar to Malcolm McLaren.

The second modification, involving 89 pistols, featured a similar frame extension, but the forward grip had wooden panels and was of different shape.

) This was so successful that application software and operating system software above the LIC layer that were compiled on the original S / 38 run without modification and without recompilation on the latest AS / 400 systems, despite the fact that the underlying hardware has been changed dramatically ; at least three different types of processors have been in use.

For example, a slight modification of the assumption of how growth and body size are related leads to a different conclusion, namely that for a given ecosystem, a certain range of species may coexist while others become outcompeted.