Mutation of c-kit causes the constitutive activity of tyrosine kinase which results in cancerous gastrointestinal stromal tumors.

Two types of constitutive equations are given below: One type results from using empirical relationships and includes Newtonian fluids, the Bingham fluid model and the power-law fluid model.

This results in increased production of cAMP, which activates protein kinase A, which subsequently activates lipases found in adipose tissue.

In 2012, it was shown that resveratrol is capable of competitively inhibiting various phosphodiesterases, which results in an increase in cytosolic concentration of cAMP, which acts as a second messenger for the activation of the pathway Epac1 / CaMKKβ / AMPK / SIRT1 / PGC-1α.

* For example, Cholera toxin ADP-ribosylates, thereby activating tissue adenylate cyclase to increase the concentration of cAMP, which causes the movement of massive amounts of fluid and electrolytes from the lining of the small intestine and results in life-threatening diarrhea.

An increase in cAMP results in an increase in the active form of PKA, which is directly related with an inhibition in platelet aggregation.

# Studies of recurrent febrile seizures have shown that seizures resulted in impaired learning and memory but also disrupted signaling that normally results in activation of cAMP response element binding factor ( CREB ), a transcription factor.

The results of these tests give confidence to the clients as to how the system will perform in production.

In simpler term, Biotechnology is the research and development in the laboratory that involves bioinformatics for exploration, extraction, exploitation and production from any living organisms and any source of biomass by means of biochemical engineering where high value-added products could be planned ( reproduced by Biosynthesis, for example ), fore-casted, formulated, developed, manufactured and marketed for the purpose of sustainable operations ( for the return from bottomless initial investment on R & D ) and gaining durable patents rights ( for exclusives rights for sales, and prior to this to receive national and international approval from the results on animal experiment and human experiment, especially on the pharmaceutical branch of biotechnology to prevent any undetected side-effects on safety concerns by using the products ), for more about the biotechnology industry, see.

More general results from the study were that precipitation and water use lead to above-ground primary production, solar radiation and temperature lead to belowground primary production ( roots ), and temperature and water lead to cool and warm season growth habit.

This results in the most common side-effects of chemotherapy: myelosuppression ( decreased production of blood cells, hence also immunosuppression ), mucositis ( inflammation of the lining of the digestive tract ), and alopecia ( hair loss ).

Most production crankshafts use induction hardened bearing surfaces, since that method gives good results with low costs.

Accompanying noise from the set, equipment, traffic, wind, and the overall ambiance of the surrounding environment often results in unusable production sound, and during the post-production process a supervising sound editor or ADR Supervisor reviews all of the dialogue in the film and decides which lines will have to be re-recorded.

More total output and utility thereby results from specializing in production and trading than if each country produced its own high-tech and low-tech products.

A production function has constant returns to scale if increasing all inputs by some proportion results in output increasing by that same proportion.

The hiring of labor power only results in the production of goods or services (" use-values ") when organized and regulated ( often by the " management ").

A cointegration analysis support results derived from linear exponentional ( LINEX ) production functions.

One of the positive results of the campaign was GAR ( Golden Agri-Resources ), the world's second largest palm oil production company, deciding to commit itself to forest conservation.

In all other forms of production, there is a conflict between the supply of these requirements, since excessive or deficient amounts of one results in an imbalance of one or both of the others.

The combustion process typically results in the production of a great quantity of heat, as well as the production of steam and carbon dioxide and other chemicals at very high temperature ; the temperature reached is determined by the chemical make up of the fuel and oxidisers ( see stoichiometry ), as well as by the compression and other factors.

The object of the conference was " To consider the advisability of all maritime nations adopting similar methods in preparation, construction, and production of their charts and all hydrographic publications ; of rendering the results in the most convenient form to enable them to be readily used ; of instituting a prompt system of mutual exchange of hydrographic information between all countries ; and of providing an opportunity to consultations and discussions to be carried out on hydrographic subjects generally by the hydrographic experts of the world.

Meeting with Feklisov six times, he provided the results of the test at Eniwetok atoll of uranium and plutonium bombs and the key data on U. S. production of uranium-235.

Inevitably, both the Bomber B and Amerika Bomber programs were victims of the continued emphasis of the Wehrmacht's insistence for the Luftwaffe to support the Army as its primary mission, as well as the increasingly devastating results of the RAF Bomber Command at night, and by 1943 the USAAF's Eighth and Fifteenth Air Forces ' heavy bomber raids by daylight on the German aviation industry, which catastrophically diminished the Third Reich's overall aviation production capacity later in World War II.

This was the first major war in Europe between industrialized countries, and the first time in Western Europe that the results of industrialization ( for example, mass production ) had been dedicated to war.

Nonetheless, a pure monopoly can – unlike a competitive company – alter the market price for its own convenience: a decrease of production results in a higher price.

This results in the production of gametes which have either too many or too few of a particular chromosome, and is a common mechanism for trisomy or monosomy.

Instead, since development of music involves man's power, it reduces production of food ; furthermore, appreciation of music results in less time for administrative works.

" They did not discuss the implications for agriculture in depth, but noted that a 1986 study which assumed no food production for a year projected that " most of the people on the planet would run out of food and starve to death by then " and commented that their own results show that " this period of no food production needs to be extended by many years, making the impacts of nuclear winter even worse than previously thought.

Any attempt to reconcile this statement of the central issue in the campaign of 1956 with the nature of the man who could not conceive it as the central issue will at least resolve our confusions about the chaotic and misleading results of the earnestness of both doctors and President in a situation which should never have arisen.

He will not be surprised to find that general principles produce conflicting results in the factual situation with which he is confronted.

A completely new insight into living cells and their structure will be possible by use of a new technique which replaces visible light with ultraviolet radiation and combines a microscope with a color-TV system to view the results.

The results of present observations of the thermal radio emission of the moon are consistent with the very low thermal conductivity of the surface layer which was derived from the variation in the infrared emission during eclipses ( e.g., Garstung, 1958 ).

This calculation results in an enthalpy rise which is somewhat high because it assumes a mass flow equally distributed over the plug cross section whereas in reality the mass velocity is expected to be smaller in the regions of higher temperatures.

-- Although there was some variation in results which must be attributed either to trace impurities or to variation in wall effects, the photochemical exchange in the gas phase was sufficiently reproducible so that it seemed meaningful to compare the reaction rates in different series of reaction tubes for the purpose of obtaining information on the effect of chlorine concentration and of carbon tetrachloride concentration on the reaction rate.

The first possibility results in a closed interval of tangent points in the f-plane, the end points of which fall into category ( B ) or ( C ).

However, the regionally differentiated results, which appear below in tables, are interesting evidence of the problems of developing self-government under even the most favorable circumstances.

Interesting evidence can be found in the results of the Chamber of Commerce elections, which took place three weeks before national elections.

The instrumental method, however, is about 100 times more sensitive and yields numerical results which can be accurately repeated at will over a period of time.

The results were good, but which treatment helped is still not known.

Moreover, prudence alone would indicate that, unless the local customs are already ready to fall when pushed, the results of direct economic action everywhere upon national chain stores will likely be simply to give undue advantage to local and state stores which conform to these customs, leading to greater decentralization and local autonomy within the company, or even ( as the final self-defeat of an unjust application of economic pressure to correct injustice ) to its going out of business in certain sections of the country ( as, for that matter, the Quakers, who once had many meetings in the pre-Civil War South, largely went out of business in that part of the country over the slavery issue, never to recover a large number of southern adherents ).

The debate is interesting enough, however, that it is considered of note when a theorem in ZFC ( ZF plus AC ) is logically equivalent ( with just the ZF axioms ) to the axiom of choice, and mathematicians look for results that require the axiom of choice to be false, though this type of deduction is less common than the type which requires the axiom of choice to be true.

Some results in constructive set theory use the axiom of countable choice or the axiom of dependent choice, which do not imply the law of the excluded middle in constructive set theory.

There are several results in category theory which invoke the axiom of choice for their proof.

The crystal lattice of solid americium and its compounds contains intrinsic defects, which are induced by self-irradiation with alpha particles and accumulate with time ; this results in a drift of some material properties.

These results refined Ernest Rutherford's and Antonius Van den Broek's model, which proposed that the atom contains in its nucleus a number of positive nuclear charges that is equal to its ( atomic ) number in the periodic table.

# Utilitarianism, where the practical consequences of various policies are evaluated on the assumption that the right policy will be the one which results in the greatest happiness

And some have fear, which results from foul deeds in the former life or from insistent haughtiness.

In their 1999 study of the Prime Ministers of Canada, which included the results of a survey of Canadian historians, J. L.

Breakdown of the relatively scentless ambrein through oxidation results in the formation of ambrox and ambrinol, which are the main odour components of ambergris.

In Tales from the Crypt # 44 a plague-stricken man is eaten by a sperm whale, which produces ambergris that results in a cursed perfume.

* 1907 – Count Alexander Izvolsky and Sir Arthur Nicolson sign the St. Petersburg Convention, which results in the Triple Entente alliance.

This results in an intelligibility problem because wrat can easily be confused for aurat, which means woman instead of fast in Hindi-Urdu.

While one-third of alternative treatments have some published literature supporting their use, research on alternative medicine is frequently of low quality and methodologically flawed, which might cause these results to be exaggerated.