While the atypical ( second-generation ) antipsychotics were marketed as offering greater efficacy in reducing psychotic symptoms while reducing side effects ( and Extrapyramidal symptoms in particular ) than typical medications, the results showing these effects often lacked robustness, and the assumption was increasingly challenged even as atypical prescriptions were soaring.

While controlled clinical trials of atypicals reported that extrapyramidal symptoms occurred in 5 – 15 % of patients, a study of bipolar disorder in a real world clinical setting found a rate of 63 %, questioning the generalizability of the trials.

While some people with bipolar disorder mainly experience manic symptoms, others more often feel depressed.

While they are not major teratogens, uncertainty remains as to whether they cause cleft palate in a small number of babies and whether neurobehavioural effects occur as a result of prenatal exposure ; they are known to cause withdrawal symptoms in the newborn.

While medication for bipolar disorder is important to manage symptoms of mania and depression, studies show relying on medications alone is not the most effective method of treatment.

While NMT symptoms may fluctuate, they generally don't deteriorate into anything more serious and with the correct treatment the symptoms are manageable.

While another doctor called Guncelin, recognizing the symptoms of poisoning, was able to rescue the Duke from an imminent death, causing severe vomiting and cleansing the body ; but the assassin wasn't discovered, and this time put the poison in the knife used by Henry IV to cut his bread.

While proponents note that DID is accompanied by genuine suffering and the distressing symptoms, and can be diagnosed reliably using the DSM criteria, they are skeptical of the traumatic etiology suggested by proponents.

While otherwise similar, the diagnostic criteria for children also specifies symptoms must not be confused with imaginative play.

While sleep, sleep walking, dreaming, delirium and comas may signal the presence of unconscious processes, these processes are not the unconscious mind itself, but rather symptoms.

While it is not currently possible to reverse the underlying illness, there is some evidence that treatments that focus solely upon the symptoms may improve quality of life.

While the neurodegenerative condition Parkinson's disease ( PD ) is the most common cause of parkinsonism, a wide-range of other etiologies may lead to a similar set of symptoms, including some toxins, a few metabolic diseases, and a handful of non-PD neurological conditions.

While effective in some patients, they induce unpleasant menopausal symptoms, and over time may lead to osteoporosis.

While illness symptoms resolve in a day or two, the skin may take weeks to return to normal.

While negative affectivity significantly predicted BPD symptoms, this relationship was greatly reduced when thought suppression was introduced into the model.

While vocational achievement was generally more limited even compared to those with other personality disorders, those whose symptoms had remitted were significantly more likely to have a good relationship with a spouse / partner and at least one parent, good work / school performance, a sustained work / school history, good global functioning and good psychosocial functioning.

While the majority of the known types of HPV cause no symptoms in most people, some types can cause warts ( verrucae ), while others can – in a minority of cases – lead to cancers of the cervix, vulva, vagina, penis, oropharynx and anus.

While no genetic syndrome is capable of being cured, treatments are available for some symptoms.

While under hypnosis, Breuer's patients were able to recall traumatic experiences, and through the process of expressing the original emotions that had been repressed and forgotten, they were relieved of their symptoms.

While rectal bleeding or anemia are high-risk features in those over the age of 50, other commonly described symptoms including weight loss and change in bowel habit are typically only concerning if associated with bleeding.

While some researchers believe this categorization system will help physicians understand IBS, others have questioned the value of the system and suggested that all IBS patients have the same underlying disease but with different symptoms.

While white is the coolest summer shade, there are lots of pastel hues along with tintable fabrics that will blend with any wardrobe color.

While it is easy enough to ridicule Hawkins' pronouncement in Pleas Of The Crown from a metaphysical point of view, the concept of the `` oneness '' of a married couple may reflect an abiding belief that the communion between husband and wife is such that their actions are not always to be regarded by the criminal law as if there were no marriage.

While there are now allegations of the withholding of `` favorable evidence developed at the hearing '' and a denial of a `` full and fair hearing '', no such claim was made by petitioner at any stage of the administrative process.

While 2-year-olds are still gaining most of the attention at the track, green horses are starting to go a bit, and Jimmy Cruise has several that can really make it.

While individual sportsmen are aware of this situation, too many of our political, social, educational and even religious leaders too often forget it.

While some suppression and some denial are not only necessary but healthy, the worker's clinical knowledge must determine how these defenses are being used, what healthy shifts in defensive adaptation are indicated, and when efforts at bringing about change can be most effectively timed.

While there are many different possibilities for the timing of casework intervention, the experiments recently reported from a variety of traditional settings all point up the importance of an immediate response to the client's initial need for help.

While the interpretations that have been given are inferences only, they gain support from such comments as the following, which was made by one of the Kohnstamm-negative subjects who did not, on the first trial, perceive the tilt illusion.

While this influence is a complex matter, depending upon personality factors in the individual as well as upon his social-class experience, there probably are some general statements about social-class background and educational policy that can be made with a fair degree of truth.

While costs on this order are sometimes separately charged for in residential and commercial rates, in the form of a mere `` service charge '', they are more frequently wholly or partly covered by a minimum charge which entitles the consumer to a very small amount of gas or electricity with no further payment.

While ATP appears to be necessary for the occurrence of contraction, its presence and enzymatic hydrolysis of it by the muscle protein myosin are not the only criteria for contraction.

While there are still many bugs to be ironed out, the technique is fast developing.

While nowadays we recognize the fact that there are many causes for bleeding at the nose, not long ago a nosebleed was simply that, and treatment had little variation.

Many years later ( on August 3, 1915 ), Lucy Upton wrote Winslow's daughter soon to be graduated from Smith College: `` While I love botany which, after dabbling in for years, I studied according to the methods of that day exactly forty years ago in a summer school, it must be fascinating to take up zoology in the way you are doing.

While patent suits are still among the most complex and expensive forms of litigation, these rules have saved litigants uncounted sums of money.

While details are still to be worked out, Ratcliff said he expects to tell home folks in Dallas why he thinks Berry's proposed constitutional amendment should be rejected.

While availability of mortgage money has been a factor in encouraging apartment construction, the generally high level of prosperity in the past few years plus rising consumer income are among the factors that have encouraged builders to concentrate in the apartment-building field.

While it must be said that these same Protestants have built some new churches during this period, and that religious population shifts have emptied churches, a principal reason for this phenomenon of redundancy is that fewer Protestants are going to church.

While we are filling outer space with scientific successes, for many the `` inner '' space of their soul is an aching void.

While there is general agreement on these six families, there are some points of disagreement among linguists who study Afroasiatic.

While most alphabets have letters composed of lines ( linear writing ), there are also exceptions such as the alphabets used in Braille, fingerspelling, and Morse code.