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The use of D. purpurea extract containing cardiac glycosides for the treatment of heart conditions was first described in the English-speaking medical literature by William Withering, in 1785, which is considered the beginning of modern therapeutics. It is used to increase cardiac contractility ( it is a positive inotrope ) and as an antiarrhythmic agent to control the heart rate, particularly in the irregular ( and often fast ) atrial fibrillation.
Despite this uncertainty, fourteen individuals have been identified as having verifiably attended Lunar Society meetings regularly over a long period during its most productive eras: these are Matthew Boulton, Erasmus Darwin, Thomas Day, Richard Lovell Edgeworth, Samuel Galton, Jr., James Keir, Joseph Priestley, William Small, Jonathan Stokes, James Watt, Josiah Wedgwood, John Whitehurst and William Withering.
William Withering – like Small a physician – was already an acquaintance of Darwin, Boulton and Wedgwood when he moved from Stafford to Birmingham and became a member of the Society in 1776.
The botanist and physician Jonathan Stokes, who had known William Withering as a child, moved to Stourbridge and started attending Lunar Society meetings from 1783.
William Withering ( 17 March 1741 – 6 October 1799 ) was an English botanist, geologist, chemist, physician and the discoverer of digitalis.
Withering wrote two more editions of this work in 1787 and 1792, in collaboration with fellow Lunar Society member Jonathan Stokes, and after his death his son ( also William ) published four more.
The William Withering Chair in Medicine at the University of Birmingham Medical School is named after him, as is the medical school's annual William Withering Lecture.
William Withering analysing thermal waters in Portugal He was an enthusiastic chemist and geologist.
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