Her half-aunt, the future Queen Isabella I of Castile, was due to inherit the crown, but Afonso V was keen to interfere with the succession in Castile.

After the indecisive < ref name =" British historian Townsend Miller "> British historian Townsend Miller: “ But, if the outcome of < nowiki > battle of </ nowiki > Toro, militarily, is debatable, there is no doubt whatsoever as to its enormous psychological and political effects ” in The battle of Toro, 1476, in History Today, volume 14, 1964, p. 270 </ ref > Battle of Toro in 1476 against King Ferdinand II of Aragon, the husband of Isabella I of Castile, he went to France to obtain the assistance of Louis XI, but finding himself deceived by the French monarch, he returned to Portugal in 1477 in very low spirits.

He was the father of three future rulers of Jerusalem, Sibylla, Baldwin IV, and Isabella I.

After Eschiva's death in October 1197 he married Isabella, the daughter of Amalric I of Jerusalem by his second marriage, and became King of Jerusalem in right of his wife and crowned at Acre in January 1198.

The marriage of Ferdinand II of Aragon and Isabella I of Castile in 1469 united the two royal lines.

She was the youngest surviving child of King Ferdinand II of Aragon and Queen Isabella I of Castile.

At an early age, Catherine was considered a suitable wife for Arthur, Prince of Wales, the eldest son of Henry VII of England and heir to the throne, due to the English ancestry she inherited from her mother Queen Isabella I of Castile.

In 1501, the Spanish monarchs, Ferdinand I and Isabella, first granted permission to the colonists of the Caribbean to import African slaves, which began arriving to the island in 1503.

* 1469 3 June – After the death of Alfonso de Castilla and the 1st Duke of Medina Sidonia, his son and heir Enrique de Guzman, 2nd Duke of Medina Sidonia changed side and in reward, saw the status of Gibraltar, as part of the domains of the Duke, confirmed by the Queen Isabella I of Castile.

* 1479 20 January – Queen Isabella I of Castile and King Ferdinand II of Aragon – the Catholic Monarchs, jointly rule the kingdoms of Castile and Aragon, including Gibraltar.

* 1502 2 January – Garcilaso de la Vega took possession of the town on behalf of the Queen Isabella I of Castile.

The Coat of arms of Gibraltar | arms granted to the city of Gibraltar by a Royal Warrant passed in Toledo, Spain | Toledo on 10 July 1502 by Isabella I of Castile

* 1502 10 July – By a Royal Warrant passed in Toledo by Isabella I of Castile, Gibraltar was granted its coat of arms: " An escutcheon on which the upper two thirds shall be a white field and on the said field set a red castle, and below the said castle, on the other third of the escutcheon, which must be a red field in which there must be a white line between the castle and the said red field, there shall be a golden key which hangs by a chain from the said castle, as are here figured ".

Contenders for the throne of Castile were Henry's one-time heir Joanna La Beltraneja, supported by Portugal and France, and Henry's half-sister Queen Isabella I of Castile, supported by the Kingdom of Aragon and by the Castilian nobility.

Leonora was the daughter of Ferdinand I, the Aragonese King of Naples, and Isabella of Taranto.

* I camerini di Isabella d ' Este Mantua tourist guide.

* 1492 – The first grammar of the Spanish language is presented to Queen Isabella I.

In June the Haute Cour granted the regency to Alice of Champagne, who, as the daughter of Isabella I, was Conrad's great-aunt and his closest relative living in the kingdom.

Plaisance died in 1261, but as her son Hugh II was still underage, Cyprus passed to his cousin Hugh of Antioch-Lusignan, whose mother Isabella of Cyprus, Alice of Champagne and Hugh I of Cyprus ' daughter and Hugh II's aunt, took over the regency in Acre.

This was disputed by another branch of the Lusignan family: Maria of Antioch, daughter of Bohemond IV of Antioch and Melisende of Lusignan ( herself a daughter of Isabella I and Amalric II ), claimed the throne as the oldest living relative of Isabella I, but for the moment her claim was ignored.

For Spain, dates commonly used are the death of King Ferdinand II in 1516, the death of Queen Isabella I of Castile in 1504, or the conquest of Granada in 1492.

Melilla was part of the Kingdom of Fez when the Catholic Monarchs, Queen Isabella I of Castile and King Ferdinand II of Aragon requested Juan Alfonso Pérez de Guzmán, 3rd Duke of Medina Sidonia, to take the city.

** Isabella of Jerusalem, Queen of Jerusalem 1190 / 1192 – 1205 ( d. 1205 )

* Maria of Montferrat ( 1192 – 1212 ), queen regnant of Jerusalem, daughter of Isabella I of Jerusalem and Conrad of Montferrat and mother of Isabella II of Jerusalem

Her legal successor was her half-sister Isabella, who was forced to end her marriage to Humphrey of Toron and instead to marry Conrad, but Guy refused to relinquish his crown until an election in 1192.

Isabella I ( 1172 – 5 April 1205 ) was Queen regnant of Jerusalem from 1190 / 1192 until her death.

# Maria ( 1192 – 1212 ), succeeded Isabella as Queen of Jerusalem.

Maria of Montferrat ( or Maria of Jerusalem ) ( 1192 – 1212 ) was Queen of Jerusalem, the daughter of Conrad of Montferrat and Isabella, Queen of Jerusalem.

* 1566 – Isabella Clara Eugenia Spanish wife of Albert VII, Archduke of Austria ( d. 1633 )

Joan of England, ( 22 July 1210 – 4 March 1238 ), was the eldest legitimate daughter and third child of John of England and Isabella of Angoulême.

* 1200 – King John of England, signee of the first Magna Carta, marries Isabella of Angouleme in Bordeaux Cathedral.

* 2007 – Princess Isabella of Denmark

** Isabella II ( 1833 – 1868 )

* 1241 – Isabella of England, wife of Frederick II, Holy Roman Emperor ( b. 1214 )

* 1633 – Infanta Isabella Clara Eugenia of Spain ( b. 1566 )

* 1958 – Isabella Hofmann, American actress

* 1327 – Teenaged Edward III is crowned King of England, but the country is ruled by his mother Queen Isabella and her lover Roger Mortimer.

* 2001 – Isabella Acres, American actress

Ferdinand – resisting the wishes of his brother – decreed the Pragmatic Sanction of 1830, enabling his daughter Isabella to become Queen.

Ferdinand's death in 1833 and the accession of Isabella II as Queen of Spain sparked the First Carlist War ( 1833 – 1839 ).

Isabella II of Spain took a more active role in government after coming of age, but she was immensely unpopular throughout her reign ( 1833 – 1868 ).

Isabella d ' Este ( 19 May 1474 – 13 February 1539 ) was Marchesa of Mantua and one of the leading women of the Italian Renaissance as a major cultural and political figure.

* Ferrante Gonzaga ( 28 January 1507 – 15 November 1557 ), a condottiero ; married Isabella di Capua, by whom he had issue.

* 1952 – Isabella Rossellini, Italian actress

* 1789 – María Isabella of Spain ( d. 1846 )

* 1332 – Isabella de Coucy, English daughter of Edward III of England ( d. 1382 )

* 1492 – Ferdinand and Isabella The Catholic Monarchs enter Granada, completing the Reconquista.