* Isotretinoin ( Tradename: Accutane ( US ), Roaccutane )

* Accutane ( Isotretinoin ), which is a powerful derivative of Vitamin A, rarely causes Papilledema.

* Isotretinoin ( Accutane )

Isotretinoin has been shown to be very effective in treating severe acne and can either improve or clear well over 80 % of patients.

Podophyllin, podofilox and Isotretinoin should not be used during pregnancy, as they could cause birth defects in the fetus.

* Oral Isotretinoin is a therapy that has proven effective in experimental use, but is rarely used due to potentially severe side effects.

Isotretinoin is a drug used to treat cystic acne.

Isotretinoin is not only considered the only known possible cure of acne in some patients, but was originally a chemotherapy treatment for certain cancers, such as leukemia.

Its acne drug isotretinoin, marketed as Accutane and Roaccutane, also used as a form of chemotherapy for some cancers, has been linked with a number of severe side effects and remains highly controversial but highly effective at the same time.

A daily oral intake of vitamin A derivative isotretinoin ( marketed as Roaccutane, Accutane, Amnesteem, Sotret, Claravis, Clarus ) over a period of 4 – 6 months can cause long-term resolution or reduction of acne.

This preceded the development of oral isotretinoin ( sold as Accutane and Roaccutane ) in 1980.

* Birth defects associated with thalidomide and isotretinoin ( Accutane )

* High-risk neuroblastoma is treated with intensive chemotherapy, surgery, radiation therapy, bone marrow / hematopoietic stem cell transplantation, biological-based therapy with 13-cis-retinoic acid ( isotretinoin or Accutane ) and antibody therapy usually administered with the cytokines GM-CSF and IL-2.

It may occur as a complication of taking Accutane ( isotretinoin ) during pregnancy.

Further, most prescription or over the counter acne medications ( e. g. Accutane, Benzoyl Peroxide, Retin-A ), when used in combination with ultraviolet exposure, may lead to burning or delayed healing due to photosensitivity that these drugs ( and many others ) can create.

* 1980s: Accutane is introduced in the United States, and later found to be a teratogen, highly likely to cause birth defects if taken during pregnancy.

* Several scientific studies have posted that Accutane is a possible trigger of Crohn's Disease and Ulcerative colitis in some individuals.

Drugs produced by Roche include Xenical, Valium, Dormicum, Klonopin, Roaccutane, Avastin, Accutane, MabThera, Herceptin, Valcyte, Tarceva, Invirase, Boniva, Rohypnol, Xeloda, Tamiflu, Zelboraf and Erivedge.

In summer 2010 Marshall sued the pharmaceutical company Hoffmann-LaRoche ( a unit of Roche Holding AG ) for $ 11 million in damages for injuries which, he claimed, resulted from his taking the drug Accutane.

Roche had removed Accutane from the market in 2009 due to a spate of similar claims.

His long nose wiggled at the smells of frizzling bacon and heating java, but the fire was low, and he wanted to waste no time.

Others are confined to vast reservations, and not only does the Australian government justifiably not wish them to be viewed as exhibits in a zoo, but on their reservations they are extremely fugitive, shunning camps, coming together only for corroborees at which their strange culture comes to its highest pitch -- which is very low indeed.

Master Gorton, having foully abused high and low at Aquidneck is now bewitching and bemaddening poor Providence, both with his unclean and foul censures of all the ministers of this country ( for which myself have in Christ's name withstood him ), and also denying all visible and external ordinances in depth of Familism: almost all suck in his poison, as at first they did at Aquidneck.

As we looked more intently at the content of our belief and the extent of religious participation, we received the impression that many of the religious convictions expressed represented a conventional acceptance, of low intensity.

After a tortuous drive in an open truck and a World War 2, army jeep down soggy trails, the band arrived at a small clearing squeezed between a long, low ridge and a creek-filled gully.

Here, too, she talked low, quirking her head at one or another of the places, most often at Izaak's armchair which faced her across the long table.

Since conventional methods are insensitive at the low frequencies of these molecular transitions, the paramagnetic resonance method is being used instead.

This caution has been particularly noticeable in a tendency of retailers and distributors to shift the inventory burden back on the supplier, and the fact stocks at retail are low in many lines has escaped attention because of the presence of higher stocks at the manufacturing level.

Taking the path behind the Throne Room to the building directly beyond it, the Portrait Gallery, I went right at the end of it, through a garden to a small building at the back -- a sitting room furnished with low blue divans, its floor covered with carpets, its ceiling painted with gold squares and floral designs.

A new low capacity meter is the key that unlocks the situation at Oakwood Heights.

Its high impact strength, even at low temperatures, resists chipping, cracking, and crazing, according to Du Pont.

No attempts to measure the radio emission of the remaining planets have been reported, and, because of their distances, small diameters, or low temperatures, the thermal radiation at radio wave lengths reaching the earth from these sources is expected to be of very low intensity.

Measurements of polarization are presently limited by apparatus sensitivity and will remain difficult because of the low intensity of the planetary radiation at the earth.

Argon was also blown at low velocities ( mass flow rate Af ) through a tube coaxial with the cathode as an additional precaution against contamination of the arc by air.

Essentially these birefringence studies show that at low rates of shear a tension is present at 45-degrees to the direction of shear, and as the rate of shear increases, the direction of the maximum tension moves asymptotically toward the direction of shear.

Mason and Taylor both show that the major axis of the ellipsoids is at 45-degrees at low rates of shear and that it approaches the direction of shear with increased rates of shear.

One sample, which had been exposed to the atmosphere after evacuation at 375-degrees-C, showed the presence of adsorbed water ( about 0.3 wt ) ) as evidenced by a weak resonance line which was very narrow at room temperature and which disappeared, due to broadening, at low temperature.

It is preferred that benzodiazepines be taken intermittently and at the lowest effective dose.

Some say he died after prolonged suffering following a single dose at dinner, and some have him recovering only to be poisoned again.

Increases in dose at a rate of 200 mg every 1 – 2 weeks may be required to achieve a stable seizure threshold.

Dosage of chemotherapy can be difficult: If the dose is too low, it will be ineffective against the tumor, whereas, at excessive doses, the toxicity ( side-effects, neutropenia ) will be intolerable to the patient.

Patients not responding sufficiently to the first dose are sometimes given an additional radioiodine treatment, at a larger dose.

Preferably they should be prescribed for only a few days at the lowest effective dose, and avoided altogether wherever possible in the elderly.

* a basal dose that is pumped continuously at an adjustable basal rate to deliver insulin needed between meals and at night.

* 1983 Codex Alimentarius General Standard for Irradiated Foods: any food at a maximum " overall average dose " of 10 kGy

Food irradiation is sometimes referred to as " cold pasteurization " or " electronic pasteurization " because ionizing the food does not heat the food to high temperatures during the process, as in heat-pasteurization ( at a typical dose of 10 kGy, food that is physically equivalent to water would warm by about 2. 5 ° C ).

Several national expert groups came to the same result ; on top of all two international expert groups have in full detail evaluated the available data and finally concluded that any food at any dose is wholesome and safe to consume as long as it remains palatable and maintains its technical properties.

In this process, ions are implanted at a high enough energy and dose into a material to create a layer of a second phase, and the temperature is controlled so that the crystal structure of the target is not destroyed.

In a study conducted at the U. S. Army Medical Research Institute of Infectious Diseases ( USAMRIID ), treatment with ST-193 once a day for 14 days resulted in significant reduction in mortality ( 71 % of the animals survived at the low dose ), whereas all untreated animals and those treated with ribavirin died within 20 days of the infection.

For conditions other than shift work sleep disorder, modafinil is normally taken in one dose in the morning or in two doses in the morning and at midday.

In the United States addiction clinics typically start patients at a low dose, generally only starting patients on methadone when they are in withdrawal and providing a small test dose, after which the patients are observed for possible adverse effects.

However, Methadone has much lower cross-tolerance, when switching to it from other opioids, than other opioids .< ref > This means that Methadone can start at a low dose, and the time for the next switch will be longer.

Many patients report that Methadone's sedation effect is often less pronounced than with other opioids and cite this as a major argument for preferring Methadone as an analgesic .< ref > Persons reciveing MMT should not suffer from extreme sedation as a resullt of the treatment, due to the fact that a properly prescribed person will have had their dose titrated up to the optimal level to remove the effects of withdrawl, a point at which sedation should not be evident.

When detoxing at a recommended rate ( typically 1-2 mgs per week ), withdrawal is either minimal or nonexistent, as the patient's body has time to adjust to each reduction in dose.

In studies done on Methadone users going through detox, individuals experienced different withdrawal symptoms and withdrawal periods even though they received their last dose at the same time.

By précised targeting and concentrating drug at the location of obstruction, the dose used is less than 1 / 50th of the normal dose.

Among QCT's advantages: it can be performed at axial and peripheral sites, can be calculated from existing CT scans without a separate radiation dose, is sensitive to change over time, can analyze a region of any size or shape, excludes irrelevant tissue such as fat, muscle, and air, and does not require knowledge of the patient's subpopulation in order to create a clinical score ( e. g. the Z-score of all females of a certain age ).